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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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larger decrease » marked decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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223761
Image 12_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif
Published 2024“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”
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223762
Image_3_B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.tif
Published 2020“…These findings suggest that targeting B cell and CD4 T cell interaction may be a therapeutic strategy to limit atherosclerosis progression.…”
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223763
Data_Sheet_7_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP
Published 2022“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”
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223764
DataSheet_1_Assessing the potential for resource competition between the Kerguelen Plateau fisheries and southern elephant seals.docx
Published 2022“…However, the unique life history and highly polygynous nature of this species, and the lack of evidence of a measurable effect on either the seal’s population growth rates or the catch per unit of the fishery, suggest that any indirect ecological interactions are not of sufficient magnitude to affect either the seal population or the fishery.…”
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223765
Presentation_3_Precision immunointerception of EGFR-driven tumorigenesis for lung cancer prevention.pptx
Published 2023“…In this study, we identified immunogenic epitopes for the common EGFR mutations in humans and formulated a multi-peptide vaccine (E<sup>mut</sup> Vax) targeting the EGFR L858R, T790M, and Del19 mutations. …”
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223766
Table_6_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.xlsx
Published 2022“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”
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223767
DataSheet_1_Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.pdf
Published 2022“…<p>Chronic inflammation is widely observed in aging, but it is unclear whether extracellular vesicles (EVs) play a role in chronic disease-associated senescence. …”
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223768
DataSheet2_Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα).doc...
Published 2021“…<p>Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. …”
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223769
Mammographic compression in Asian women
Published 2017“…The mammograms were processed using a volumetric breast density (VBD) measurement software (Volpara) to assess compression force, compression pressure, compressed breast thickness (CBT), breast volume, VBD and MGD against breast contact area. …”
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223770
Data_Sheet_1_Bilateral Superior Cervical Sympathectomy Activates Signal Transducer and Activator of Transcription 3 Signal to Alleviate Myocardial Ischemia-Reperfusion Injury.pdf
Published 2022“…Studies have increasingly found that the signal transducer and activator of transcription 3 (STAT3) plays a protective role in myocardial I/R injury. However, the precise mechanism is unknown. …”
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223771
Image4_Mid-Late Holocene Sub-Millennial Scale Inverse Trends of South Asian Summer and Winter Monsoons in Sri Lanka.jpg
Published 2021“…Multiple proxies (diagnostic biomarkers, hydrogen and carbon isotopes of individual n-alkane, grain size, and Zr/Rb elemental ratio) indicate a sub-millennial scale decreasing trend of summer monsoon rainfall in the wet zone of Sri Lanka alongside an increasing trend of winter monsoon rainfall in the dry zone during the last ∼6000 years. …”
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223772
Video_1_Surface-Induced Formation and Redox-Dependent Staining of Outer Membrane Extensions in Shewanella oneidensis MR-1.AVI
Published 2019“…While previous studies focused on the display of S. oneidensis outer membrane extensions (OMEs) as a response to oxygen limitation, we find that cell-to-surface contact is sufficient to trigger the production of OMEs, including some that reach >100 μm in length, irrespective of medium composition, agitation, or aeration. …”
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223773
DataSheet_2_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx
Published 2021“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”
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223774
The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation
Published 2018“…Taken together, our study describes a new function for BNIP3 in the regulation of cellular proliferation.…”
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223775
Data_Sheet_1_Effects of Systemic Physiology on Mapping Resting-State Networks Using Functional Near-Infrared Spectroscopy.DOCX
Published 2022“…In the present work, we hypothesized that additional measurements with short channels, heart rate, mean arterial pressure, and end-tidal CO<sub>2</sub> could provide a better understanding of the effects of systemic physiology on fNIRS-based resting-state networks. …”
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223776
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223777
DataSheet1_Metformin reduces basal subpopulation and attenuates mammary epithelial cell stemness in FVB/N mice.docx
Published 2024“…These insights suggest that the regulatory effects of metformin on premalignant mammary tissues could potentially delay or prevent the onset of breast cancer, offering a promising avenue for developing new preventive strategies.…”
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223778
Data_Sheet_1_Cost-effectiveness of Paxlovid in reducing severe COVID-19 and mortality in China.docx
Published 2023“…</p>Materials and methods<p>Using a Markov model, two interventions by Paxlovid prescription (with and without prescription) were compared in terms of COVID-19-related clinical outcomes and economic loss. …”
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223779
Spatially Extensive Standardized Surveys Reveal Widespread, Multi-Decadal Increase in East Antarctic Adélie Penguin Populations
Published 2015“…East Antarctic marine ecosystems have been subject to a number of changes over the last 50 years which may have influenced Adélie penguin population growth, including decadal-scale climate variation, an inferred mid-20th century sea-ice contraction, and early-to-mid 20<sup>th</sup> century exploitation of fish and whale populations.…”
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223780
Table_2_Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice.DOCX
Published 2018“…Endotoxemia was induced in C57BL/6J mice (8 weeks old) by intravenous injection of sonicated Pg; Pg was deactivated but its endotoxin remained. The mice were fed a high-fat diet and administered sonicated Pg (HFPg) or saline (HFco) injections for 12 weeks. …”