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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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224161
DataSheet1_Huang Lian Jie Du decoction attenuated colitis via suppressing the macrophage Csf1r/Src pathway and modulating gut microbiota.docx
Published 2024“…Introduction<p>Ulcerative colitis, a subtype of chronic inflammatory bowel disease (IBD), is characterized by relapsing colonic inflammation and ulcers. …”
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224162
Baseline predictors of short-term visual outcomes after intravitreal conbercept injection for neovascular age-related macular degeneration
Published 2022“…We aimed to identify baseline predictors of visual prognosis after intravitreal conbercept injection for neovascular age-related macular degeneration. Methods: We conducted a retrospective review of 58 patients with neovascular age-related macular degeneration who were treated with intravitreal injections of conbercept 0.5 mg in routine clinical practice. …”
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224163
Image_2_Splenic SUMO1 controls systemic inflammation in experimental sepsis.jpeg
Published 2023“…In the spleen, endotoxemia induced a distinct temporal and substrate specificity for SUMO1 and SUMO2/3, and both were inhibited by TAK981. …”
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224164
Image_5_Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.JPEG
Published 2022“…In this study, we conducted a genome-wide analysis of MYB-related proteins in sweet osmanthus; 212 OfMYB-related TFs were divided into three distinct subgroups based on the phylogenetic analysis. …”
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224165
Table 1_The interaction between temperature and rainfall determines the probability of tropical forest fire occurrence in Hainan Island.docx
Published 2025“…This study integrated ground-based fire statistics from the Hainan Forestry Department and moderate resolution imaging spectroradiometer (MODIS) fire point data to create a highly accurate forest fire dataset for Hainan Island, spanning 20 years (2000–2020). …”
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224166
DataSheet_1_The value of metabolic LncRNAs in predicting prognosis and immunotherapy efficacy of gastric cancer.xlsx
Published 2023“…Introduction<p>As a unique feature of malignant tumors, abnormal metabolism can regulate the immune microenvironment of tumors. …”
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224167
DataSheet_1_3D printed Ti-5Cu alloy accelerates osteogenic differentiation of MC3T3-E1 cells by stimulating the M2 phenotype polarization of macrophages.docx
Published 2022“…In this study, we prepared Ti-5Cu alloy by three-dimensional printing technology and found that Ti-5Cu alloy presented a much smoother surface compared with Ti. In addition, the CCK-8 results indicated the Ti-5Cu alloy had no cytotoxicity to RAW264.7 cells by co-culture. …”
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224168
<b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b>
Published 2024“…These data highlight BCL6 as a novel therapeutic target in type 1 diabetes.</p>…”
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224169
Table1_Mid-Late Holocene Sub-Millennial Scale Inverse Trends of South Asian Summer and Winter Monsoons in Sri Lanka.docx
Published 2021“…Multiple proxies (diagnostic biomarkers, hydrogen and carbon isotopes of individual n-alkane, grain size, and Zr/Rb elemental ratio) indicate a sub-millennial scale decreasing trend of summer monsoon rainfall in the wet zone of Sri Lanka alongside an increasing trend of winter monsoon rainfall in the dry zone during the last ∼6000 years. …”
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224170
Table_1_Modulation of Fermentation Quality and Metabolome in Co-ensiling of Sesbania cannabina and Sweet Sorghum by Lactic Acid Bacterial Inoculants.docx
Published 2022“…<p>Sesbania cannabina (SC) is a protein-rich roughage that thrives under moderate-severe saline-alkali (MSSA) soils with the potential to relieve the shortage of high nutritive forage. …”
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224171
DataSheet1_Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics a...
Published 2024“…<p>Background: Cardiovascular diseases (CVD) continue to threaten health worldwide, and account for a significant portion of deaths and illnesses. …”
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224172
Table_1_Echocardiographic Prediction of Left Ventricular Dysfunction After Transcatheter Patent Ductus Arteriosus Closure in Children.DOCX
Published 2019“…</p><p>Conclusion: Transcatheter closure of PDA causes a significant deterioration in LV systolic function early after PDA closure, which recovered completely within 3 months of post-closure in children. …”
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224173
Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
Published 2020“…According to these and other pieces of evidence, Xrn1 seems to influence transcription elongation at least in two ways: by directly favouring elongation rates and by a more general mechanism that connects mRNA decay to late elongation.…”
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224174
Table 1_Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies.docx
Published 2025“…</p>Conclusions<p>Psychobehavioral abnormality, bowel and bladder dysfunction, and total protein of CSF were three variables associated with increased number of high-risk antibodies in PNS patients, while increased number of high-risk antibodies might indicate a poor immunotherapy response. Our findings might help to understand the association of PNS patients’ clinical features and high-risk antibodies, as well as to guide clinical practice.…”
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224175
Image_1_Porcine epidemic diarrhea virus strain FJzz1 infection induces type I/III IFNs production through RLRs and TLRs-mediated signaling.tiff
Published 2022“…In this study, we observed that various IFN-stimulated genes (ISGs) were upregulated significantly in a time- and dose-dependent manner in LLC-PK1 cells infected with the PEDV G2 strain FJzz1. …”
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224176
Gene Profile of Chemokines on Hepatic Stellate Cells of Schistosome-Infected Mice and Antifibrotic Roles of CXCL9/10 on Liver Non-Parenchymal Cells
Published 2012“…<div><p>Hepatic stellate cells (HSCs) play a key role in the development of liver fibrosis caused by schistosomiasis. …”
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224177
Image_1_Change of mortality of patients with acute ischemic stroke before and after 2015.TIF
Published 2022“…</p>Materials and methods<p>A retrospective cohort study was conducted using combined anonymized data from the Acute Stroke Assessment Registry of Korea and the Health Insurance Review & Assessment Service database. …”
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224178
Image1_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.TIFF
Published 2023“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”
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224179
Data file.
Published 2024“…The average physical domain score decreased significantly from baseline to follow-up, whereas a significant increase in average scores has been observed in other domains at the follow-up (p<0.05). …”
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224180
DataSheet4_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP
Published 2021“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”