Image_6_Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.tif by Laura Kröhn (17011479)

“…However, higher IL37 expression correlated with a reduced proinflammatory cytokine response in murine colonic organoids. …”

Image_3_ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway.TIFF by Shenglin Gao (10142900)

“…The potential mechanism affected by ATF3 was analyzed through gene set enrichment analysis (GSEA) and verified using western blotting, invasion assay, or immunofluorescence staining. Furthermore, a xenograft mouse model was used to assess the function of ATF3 in vivo.…”

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…An effective therapy for human adenovirus (HAdV) infections in immunocompromised patients and healthy individuals with community-acquired pneumonia remains an unmet medical need. We herein reported a series of novel substituted <i>N</i>-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues as potent HAdV inhibitors. …”

DataSheet_1_The Risk of Arterial Thrombosis in Patients With Chronic Myeloid Leukemia Treated With Second and Third Generation BCR-ABL Tyrosine Kinase Inhibitors May Be Explained b... by Hélène Haguet (3365288)

“…Here, we aimed to provide an in vitro homogenous evaluation of the effects of BCR-ABL TKIs on the endothelium, with a special focus on the type of cell death to elucidate the mechanisms responsible for the potential cytotoxic effects of BCR-ABL TKIs nilotinib and ponatinib on endothelial cells. …”

DataSheet8_Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic pr... by Osvaldo Contreras (780538)

“…<p>Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. …”

DataSheet1_Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathwa... by Wilbert Bouwman (9534287)

“…Differential diagnosis remains a challenge. Anti-TNFα treatment is an important treatment for IBD, yet resistance frequently occurs and cannot be predicted. …”

Proteomic analysis of the response of <i>Trichinella spiralis</i> muscle larvae to exogenous nitric oxide by Xiaoli Wang (46677)

“…Herein, we applied label-free analysis to investigate the effect of sodium nitroprusside (SNP, a NO donor compound) on the proteome of <i>T</i>. …”

Supplementary file 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.pdf by Yulia Dwi Setia (21590591)

“…</p>Discussion<p>Our findings suggested that E. pragensis infection induces a mucosal barrier dysfunction in the early phase of the infection, which possibly causes the tissue invasion of bacteria in the large intestine. …”

Table_2_LncRNA TCF7 Promotes Epithelial Ovarian Cancer Viability, Mobility and Stemness via Regulating ITGB8.docx by Changlei Su (11717234)

“…It also correlates with advanced tumor features and poor prognosis in EOC, implying its potential as a target for EOC treatment.</p>…”

Table_4_Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s Disease.pdf by Wiebke Hermann (9214145)

“…Despite the fact that sleep disturbances are a major issue in PD patients, only limited data are available regarding interactions of sleep disturbances and cognitive performance.…”

<b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b> by Justice Muvengwi (22631075)

“…Species composition difference between sites were evaluated using analysis of similarity (ANOSIM). Our results revealed a pattern where species richness, the Shannon Wiener index, and evenness increased with decreasing relict size. …”

Change STIM1 expression or function influence SOCE in HNSCC cell lines. by Ping Li (31981)

“…<p>(A)Protein level of STIM1 showed different expression in five available HNSCC cell lines. …”

Image_1_Difference of Intrahost Dynamics of the Second Human Pegivirus and Hepatitis C Virus in HPgV-2/HCV-Coinfected Patients.tif by Yuanhao Liang (8494716)

“…The different genetic diversity of HPgV-2 and HCV makes HPgV-2 a potential new model to investigate RNA virus diversity and the mechanism of viral polymerase in modulating virus replication.…”

Image_4_Risk stratification based on DNA damage-repair-related signature reflects the microenvironmental feature, metabolic status and therapeutic response of breast cancer.tif by Chunzhen Li (14835418)

“…Integrating public datasets and bioinformatics algorithms, we developed a robust prognostic signature based on 27 DRGs. …”

Table2_Geochemistry of Formation Water and Its Implications for Petroleum Source Rocks in the Fengcheng Formation, Mahu Depression, Xinjiang, China.xlsx by Jian Wang (5901)

“…From the first member to the third member of the formation, the salinity first increases and then decreases. This low-high-low trend corresponds to the initial stage of alkaline lake development followed by strong alkali formation and a final stage of water retreat. …”

Data - <i>trus</i>RNAi wing size measurement. by Saeko Takada (21616085)

“…<div><p>Toys are us (Trus) is the <i>Drosophila melanogaster</i> ortholog of mammalian Programmed Cell Death 2-Like (PDCD2L), a protein that has been implicated in ribosome biogenesis, cell cycle regulation, and oncogenesis. …”

Table_1_Metabolomics analysis of the effect of acidification on rhizosphere soil microecosystem of tea tree.xlsx by Jianghua Ye (13951983)

“…Based on correlation interaction network analysis, 59 characteristic compounds were obtained and divided into 22 categories, among which 7 categories compounds showed a significant increasing trend with the increase of soil pH, while the other 15 categories compounds showed the opposite trend. …”

Real-time PCR and western blot analysis of Mt4-mmp expression in mouse embryonic tissues. by María José Blanco (4446124)

“…<p>(A) Real-time PCR analysis was performed using cDNA prepared from E10.5, E12.5 and E14.5 WT, HT and KO mouse embryonic tissues. …”

Hypoxia Inducible Factor-2α Regulates the Development of Retinal Astrocytic Network by Maintaining Adequate Supply of Astrocyte Progenitors by Li-Juan Duan (514982)

“…HIF-2α deficiency in astrocyte progenitors may accelerate their differentiation into astrocytes, a change which greatly interferes with the replenishment of astrocyte progenitors due to insufficient time for proliferation. …”

Image_3_The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin.jpg by Meili Li (286549)

“…<p>Viperin is an interferon-inducible protein that responsible for a variety of antiviral responses to different viruses. …”