Image_2_A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis.pdf by Federica Ciregia (450383)

“…Only SAA1α and SAA2α levels were increased in ERA patients, and SAA2α appears to mostly mediate the pathological role of A-SAA. Levels of these variants, together with SAA1β, only decreased under biologic DMARD treatment but not under methotrexate monotherapy. …”

Prox1 recruits LSD1/NuRD complex components to CYP7A1 promoter and engenders repressive epigenetic changes in histone modification patterns. by Huafang Ouyang (405865)

“…(B) Knockdown of Prox1 decreases LSD1 and HDAC2 occupancy on <i>CYP7A1</i> promoter. …”

DataSheet_1_The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.zip by Zhichao Jin (248636)

“…RP9P knockdown decreased FOXQ1 expression levels in CRC cells by directly targeting miR-133a-3p via a sponge mechanism. …”

Peripapillary Retinal Nerve Fiber Layer Changes in Preclinical Diabetic Retinopathy: A Meta-Analysis by Xiaofei Chen (56655)

“…<div><p>Background</p><p>Diabetic retinopathy is a microvascular neurodegenerative disorder in diabetic patients. …”

Image_5_A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis.pdf by Federica Ciregia (450383)

“…Only SAA1α and SAA2α levels were increased in ERA patients, and SAA2α appears to mostly mediate the pathological role of A-SAA. Levels of these variants, together with SAA1β, only decreased under biologic DMARD treatment but not under methotrexate monotherapy. …”

Decreased STAT3 activation is associated with modulation of E-cadherin, N-cadherin, VEGF, MMP2 and MMP9. by Qinchuan Liang (503212)

“…<p>A representative Western blot (A), ELISA analyses (B) and gelatin zymography (C) showed that knockdown of STAT3 expression significantly decreased the phophorylation of STAT3 and the expressions of STAT3, N-cadherin, VEGF, MMP2 and MMP9, while E-cadherin expression was dramatically increased in both U251and U87 cells, indicating that STAT3 may participate in the regulation of invasiveness and metastasis in human astrocytoma.…”

The corresponding increasing and decreasing percentages of SSI-RIK compared to EM-SFM, CSF and RIK for the results given in Table 14. by Ya-Ping Wang (44525)

“…<p>The corresponding increasing and decreasing percentages of SSI-RIK compared to EM-SFM, CSF and RIK for the results given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132370#pone.0132370.t014" target="_blank">Table 14</a>.…”

Correlation matrix of the soil characteristics for data from Carlos Botelho State Park, São Paulo State, Brazil. by Débora Cristina Rother (719692)

Decreased epithelial electrical potential as well as changes in protein distribution in mice with acute salivary gland-specific ablation of matriptase. by Hongen Yin (351667)

“…Membrane potential of pierced ducts of <i>St14^LoxP/LoxP</i> mice (<i>N = </i>2) was used as a control for impaired ductal epithelium. (A) Local depletion of matriptase in SMG from AAV2-Cre animals resulted in a significant EP decrease compared with SMG from AAV2-LacZ control mice. …”

CSE-treated bronchospheres have decreased spheroid area and increased MUC5AC secretion in the lumen compared to control. by Pranjali Beri (14945400)

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Aquaglyceroporin 2 has only recently been identified as a second transporter involved in melarsoprol/pentamidine cross-resistance. …”

Data_Sheet_1_miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.PDF by Na Li (6550)

“…Furthermore, EMT was induced, as shown by increased N-cadherin, vimentin, MMP2, and MMP9 and decreased E-cadherin in the placenta accreta spectrum group and in HTR-8/SVneo cells transfected with miR-193a-3p mimics or si-EFNB2. …”

Table1_Effects of Luteinizing Hormone Releasing Hormone A2 on Gonad Development in Juvenile Amur Sturgeon, Acipenser schrenckii, Revealed by Transcriptome Profiling Analysis.XLS by Weihua Lv (3492722)

“…However, the content of testosterone (Testo) gradually decreased with LH-A2 treatment time and showed significant differences on day 3 (p < 0.05), and on days 5 and 7 (p < 0.01), compared to those in the control group. …”

Image_1_Identification and characterization of CLEC11A and its derived immune signature in gastric cancer.jpeg by Qing Zheng (659747)

“…Moreover, the flow cytometry assay showed that the knock-down of CLEC11A increased the infiltration of cytotoxic CD8+ T cells and helper CD4+ T into tumors while decreasing the percentage of M2 macrophages, MDSCs, and Tregs.…”

Methyltetrahydrofolate vs Folic Acid Supplementation in Idiopathic Recurrent Miscarriage with Respect to Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms: A Rando... by Azita Hekmatdoost (3142815)

“…<div><p>Purpose</p><p>To determine whether 5-methylenetetrahydrofolate (MTHF) is more effective than folic acid supplementation in treatment of recurrent abortion in different MTHFR gene C677T and A1298C polymorphisms.</p><p>Methods</p><p>A randomized, double blind, placebo-controlled trial conducted April 2011-September 2014 in recurrent abortion clinics in Tehran, Iran. …”

Image_1_miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.TIFF by Na Li (6550)

“…Furthermore, EMT was induced, as shown by increased N-cadherin, vimentin, MMP2, and MMP9 and decreased E-cadherin in the placenta accreta spectrum group and in HTR-8/SVneo cells transfected with miR-193a-3p mimics or si-EFNB2. …”

Table2_Effects of Luteinizing Hormone Releasing Hormone A2 on Gonad Development in Juvenile Amur Sturgeon, Acipenser schrenckii, Revealed by Transcriptome Profiling Analysis.XLS by Weihua Lv (3492722)

“…However, the content of testosterone (Testo) gradually decreased with LH-A2 treatment time and showed significant differences on day 3 (p < 0.05), and on days 5 and 7 (p < 0.01), compared to those in the control group. …”

<i>microRNA-135a-5p</i> regulates <i>NOD-like receptor family pyrin domain containing 3</i> inflammasome-mediated hypertensive cardiac inflammation and fibrosis <i>via thioredoxin-... by Hao Chen (5190)

“…Moreover, over-expression of <i>miR-135a-5p</i> resulted in inhibition of inflammatory infiltration and almost eliminated cardiac fibrosis, as evidenced by decreased Collagen (COL)-I, COL-III, a-smooth muscle actin, <i>NLRP3</i>, tumor necrosis factor-α, and interleukin-6. …”

MiR-200a and miR-200b restrain inflammation by targeting ORMDL3 to regulate the ERK/MMP-9 pathway in asthma by Xiao-Jun Duan (9279077)

“…Therefore, elevating miR-200a and miR-200b and decreasing ORMDL3 might be potential strategies for inhibition of the asthma process.…”

Table_1_Identification and characterization of CLEC11A and its derived immune signature in gastric cancer.xlsx by Qing Zheng (659747)

“…Moreover, the flow cytometry assay showed that the knock-down of CLEC11A increased the infiltration of cytotoxic CD8+ T cells and helper CD4+ T into tumors while decreasing the percentage of M2 macrophages, MDSCs, and Tregs.…”