Hydrogen Peroxide Acts on Sensitive Mitochondrial Proteins to Induce Death of a Fungal Pathogen Revealed by Proteomic Analysis by Guozheng Qin (214834)

“…<div><p>How the host cells of plants and animals protect themselves against fungal invasion is a biologically interesting and economically important problem. …”

Circulating Stromal Cell-Derived Factor 1α Levels in Heart Failure: A Matter of Proper Sampling by Lesley Baerts (823107)

“…However, the DPP4 activity was found to be significantly decreased in patients with high SDF1α levels</p><p>Conclusions</p><p>We propose that all samples for SDF1α analysis should be collected in the presence of at least a DPP4 inhibitor. …”

Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors by Yi-You Huang (1816636)

“…Finally, compound <b>2b</b> significantly decreased the arterial pressure in PAH rats and thus validated the potential of PDE10 as a novel anti-PAH target. …”

Gene Mutation in MicroRNA Target Sites of CFTR Gene: A Novel Pathogenetic Mechanism in Cystic Fibrosis? by Felice Amato (394509)

“…The expression analysis demonstrated that the c.*1043A>C increases the affinity for miR-509-3p and slightly decreases that for the miR-433. …”

Axial Diffusivity of the Corona Radiata at 24 Hours Post-Stroke: A New Biomarker for Motor and Global Outcome by Eric Moulton (825587)

“…The ratio of ipsi and contralesional AD of the CoRad (CoRad-rAD) was the strongest diffusion parameter correlated with motor NIHSS scores on day 7 and with the mRS at 3 months. A Receiver-Operator Curve analysis yielded a model for the CoRad-rAD to predict good outcome based on upper limb NIHSS motor scores and mRS with high specificity and sensitivity. …”

datasheet2_Efficacy of Antiangiogenic Drugs in the Treatment of Diabetic Macular Edema: A Bayesian Network Analysis.xlsx by Xuexue Zhang (10652687)

“…</p><p>Conclusion: The analysis confirms that ranibizumab may be the most favorable for BCVA improvement and have a stronger efficacy in decreasing CMT and IOP than other drugs when taking all the indicators into consideration. …”

Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer by Chen Zhang (66790)

“…<p>Despite surgical and intravesical chemotherapy interventions, non-muscle invasive bladder cancer (NMIBC) poses a high risk of recurrence, which significantly impacts patient survival. …”

DataSheet1_Different Monoclonal Antibodies in Myasthenia Gravis: A Bayesian Network Meta-Analysis.docx by Zhaoming Song (11475394)

“…</p><p>Results: In indicators of efficacy, patients receiving eculizumab (MD, −1.9; 95% CI, −3.2–0.76) had decreases in MG-ADL scores compared to placebo. In addition, only eculizumab (MD, −3.1; 95% CI, −4.7–1.5) and efgartigimod (MD, −1.4; 95% CI, −2.1–0.68) showed a significant difference from placebo in the amount of reduction in QMG scores, while neither of the other two monoclonal antibodies was statistically significant. …”

Data from Small herbivores and abiotic heterogeneity promote trait variation of a saltmarsh plant in local communities by Qingqing Chen (10662878)

“…Moreover, the direct effects of herbivores played a major role in promoting ITV. Small herbivores decreased genotypic diversity at the intermediate successional stage, but genotypic richness and diversity did not impact ITV. …”

Image_1_The Potential of Metabolism-Related Gene OGDHL as a Biomarker for Myocardial Remodeling in Dilated Cardiomyopathy.tif by Yaohan Tang (11426866)

“…<p>The development of dilated cardiomyopathy (DCM) is accompanied by a series of metabolic disorders, resulting in myocardial remodeling or exacerbation, while the mechanism remains not completely clear. …”

Table 1_Causal association between Parkinson’s disease and cancer: a bidirectional Mendelian randomization study.docx by Chunyan Tang (684444)

“…Background<p>Previous observational research has indicated a correlation between Parkinson’s disease (PD) and multiple cancers; but the causality remains unclear. …”

Table_1_Risk factors for severe COVID-19 in people with cystic fibrosis: A systematic review.DOCX by Vito Terlizzi (5564168)

“…Background<p>People with cystic fibrosis (CF) are considered a clinically fragile population with an intrinsic higher risk of developing severe COVID-19, though a certain variability in terms of outcomes and hospitalization has been noticed.…”

Long-Term Outcomes of Pediatric Pars Planitis: Retrospective Cohort from a Single Tertiary Center in Turkey by Aslıhan Yılmaz Çebi (21192857)

“…</p> <p>PP was defined as vitreal inflammation with snowbank or snowball formation in the absence of a related disease. Eighty-five eyes of 44 patients were included in this study. …”

Data_Sheet_1_Potential of Antithrombin III as a Biomarker of Antidepressive Effect in Major Depressive Disorder.docx by Ruize Song (11616229)

“…Previous research has identified a panel of increased proteins in patients with major depressive disorder (MDD), including antithrombin III (ATIII), as potential biomarkers of depression.…”

Image_3_Alkalinity modulates a unique suite of genes to recalibrate growth and pH homeostasis.eps by Mitylene Bailey (16471428)

“…<p>Alkaline soils pose a conglomerate of constraints to plants, restricting the growth and fitness of non-adapted species in habitats with low active proton concentrations. …”

Comparison of Oral Paracetamol versus Ibuprofen in Premature Infants with Patent Ductus Arteriosus: A Randomized Controlled Trial by Dan Dang (479261)

“…</p><p>Conclusion</p><p>This comparison of drug efficacy and safety profiles in premature infants with PDA revealed that oral paracetamol was comparable to ibuprofen in terms of the rate of ductal closure and even showed a decreased risk of hyperbilirubinemia or gastrointestinal bleeding. …”

Data_Sheet_1_A systematic review and meta-analysis of voxel-based morphometric studies of fibromyalgia.docx by Ming Xin (3112116)

“…The current study conducted a systematic review and meta-analysis of voxel-based morphometric studies in order to comprehend those alterations in brain structure in FM patients.…”

Data_Sheet_1_Effects of Methylprednisolone on Myocardial Function and Microcirculation in Post-resuscitation: A Rat Model.docx by Changsheng Wang (2287090)

“…A negative correlation emerged between the cytokine profile and microcirculatory blood flow.…”

Video_4_Comparison of Neuroendoscopic and Microscopic Surgery for Unilateral Hemilaminectomy: Experience of a Single Institution.MP4 by Wei Zeng (126658)

“…</p>Results<p>In contrast to the UHMV group, patients in the UHNV group had a significantly shorter incision length and decreased intraoperative blood loss (P < 0.05), while the operative duration (P > 0.05) showed no statistical difference. …”

Table_4_Mendelian randomization analysis revealed a gut microbiota–mammary axis in breast cancer.xlsx by Shuwan Zhang (457893)

“…For Her2+ breast cancer, an increased abundance of Genus_Ruminococcus2 was associated with a decreased risk (OR = 0.77, p = 4.91E−04, FDR = 0.04), whereas an increased abundance of Genus_Erysipelatoclostridium was associated with an increased risk (OR = 1.25, p = 6.58E−04, FDR = 0.04). …”