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51701
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51702
DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx
Published 2024“…Background<p>Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by persistent inflammatory cascades, with macrophage activation playing a pivotal role. Chitinase 1 (CHIT1), produced by activated macrophages, is a key player in this cascade. …”
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51703
Table_2_eIF6 as a Promising Diagnostic and Prognostic Biomarker for Poorer Survival of Cutaneous Melanoma.xlsx
Published 2022“…Moreover, the decreased methylation level of keratin genes suggested a new potential regulation mode of eIF6.…”
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51704
Table_4_The m6A methylation landscape, molecular characterization and clinical relevance in prostate adenocarcinoma.docx
Published 2023“…Finally, the immune characteristics analysis showed that compared with the low-risk group, the levels of M1 and M2 macrophages in the high-risk group significantly increased, while the levels of mast cells resting and T cells CD4 memory resting significantly decreased.</p>Conclusions<p>This study provides novel findings that can further the understanding of the role of m6A methylation during the progression of PCa, which may facilitate the invention of targeted therapeutic drugs.…”
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51705
Perioperative Intravenous Acetaminophen Attenuates Lipid Peroxidation in Adults Undergoing Cardiopulmonary Bypass: A Randomized Clinical Trial
Published 2015“…The effect of acetaminophen on lipid peroxidation in adults has not been studied. This was a pilot study designed to test the hypothesis that acetaminophen attenuates lipid peroxidation in adults undergoing CPB and to generate data for a clinical trial aimed to reduce acute kidney injury following cardiac surgery.…”
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51706
Image_1_Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep model.tiff
Published 2022“…Serum OVAC concentrations peaked at 4.9 µg/ml 6 weeks after IM EP, after which levels gradually decreased but remained detectable around 0.2 to 0.3 µg/ml throughout a 13-month follow-up. …”
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51707
Image_2_Disentangling Environmental Effects on the Tree Species Abundance Distribution and Richness in a Subtropical Forest.TIFF
Published 2021“…<p>As a transitional vegetation type between evergreen broadleaved forest and deciduous broadleaved forest, evergreen-deciduous broadleaved mixed forest is composed of diverse plant species. …”
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51708
Data_Sheet_1_A Bibliometric Analysis of 100 Most-Cited Articles on Corneal Cross-Linking.PDF
Published 2022“…A bibliometric analysis of the top 100-cited articles was conducted in the current study. …”
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51709
DataSheet_5_The Efficacy and Safety of Probiotics for Allergic Rhinitis: A Systematic Review and Meta-Analysis.pdf
Published 2022“…Background<p>Probiotics have proven beneficial in a number of immune-mediated and allergic diseases. …”
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51710
Presentation_1_Pressure changes in the endotracheal tube cuff in otorhinolaryngologic surgery: a prospective observational study.pdf
Published 2023“…Intubation was performed after the induction of general anesthesia. A pressure transducer was connected to the pilot balloon of the endotracheal tube, and cuff pressure was continuously monitored until extubation. …”
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51711
Table 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.xlsx
Published 2024“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”
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51712
Image1_The Effects of Rhubarb for the Treatment of Diabetic Nephropathy in Animals: A Systematic Review and Meta-analysis.pdf
Published 2021“…<p>Background: Rhubarb, also known as Da Huang, is a traditional Chinese medicine, and it was often used as a laxative in the past. …”
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51713
Metformin induces significant reduction of body weight, total cholesterol and LDL levels in the elderly – A meta-analysis
Published 2018“…Both total cholesterol (-0.184 mmol/L, p<0.001) and LDL cholesterol levels (-0.182 mmol/L, p<0.001) decreased upon metformin-treatment.</p><p>Conclusions</p><p>Our meta-analysis of RCTs showed a small reduction of body weight together with slight improvement of the blood lipid profile in patients over 60 years. …”
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51714
Table_2_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx
Published 2024“…Background<p>Despite establishing an association between gut microbiota and spondyloarthritis (SpA) subtypes, the causal relationship between them remains unclear.…”
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51715
Table_3_In Vivo Efficacy and Toxicity of Curcumin Nanoparticles in Breast Cancer Treatment: A Systematic Review.docx
Published 2021“…<p>Breast cancer is one of the most prevalent types of malignant tumors in the world, resulting in a high incidence of death. The development of new molecules and technologies aiming to apply more effective and safer therapy strategies has been intensively explored to overcome this situation. …”
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51716
Data_Sheet_1_Elasmobranch Responses to Experimental Warming, Acidification, and Oxygen Loss—A Meta-Analysis.zip
Published 2021“…Overexploitation has been driving a worldwide decline in elasmobranch populations, and rapid environmental change, triggered by anthropogenic activities, may further test this group's resilience. …”
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51717
Data_Sheet_1_Training in psychosomatic medicine and psychotherapy for medical doctors in China: A field report.PDF
Published 2023“…Background<p>The high prevalence rates of mental disorders in China contrast a comparatively low care capacity from qualified trained medical doctors in the mental health field. …”
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51718
Acute Febrile Illness and Influenza Disease Burden in a Rural Cohort Dedicated to Malaria in Senegal, 2012–2013
Published 2015“…</p><p>Results</p><p>In Dielmo and Ndiop, the incidence of malaria has decreased, but fever syndromes remain frequent. Among the 1036 inhabitants included in the cohort, a total of 1,129 episodes of fever were reported. …”
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51719
The Effect of Hygiene-Based Lymphedema Management in Lymphatic Filariasis-Endemic Areas: A Systematic Review and Meta-analysis
Published 2015“…Participation in hygiene-based lymphedema management was associated with a lower incidence of acute dermatolymphagioadenitis (ADLA), (Odds Ratio 0.32, 95% CI 0.25–0.40), as well as with a decreased percentage of patients reporting at least one episode of ADLA during follow-up (OR 0.29, 95% CI 0.12–0.47). …”
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51720
Krt5-β-catenin-LOF results in reduced basal keratinocytes and proliferation, and leads to a smaller CVP.
Published 2017“…<p><b>(A)</b> Many proliferating Ki67<sup>+</sup> cells (magenta) are evident at the basement membrane of a control CVP, while in Krt5-β-catenin LOF mutants at 4 days and 2 weeks, fewer Ki67<sup>+</sup> cells are evident in each CVP trench. …”