Data_Sheet_1_Lipoproteins Cause Bone Resorption in a Mouse Model of Staphylococcus aureus Septic Arthritis.PDF by Michelle Schultz (12216053)

“…<p>Septic arthritis, most often caused by Staphylococcus aureus, is a rapidly progressive and destructive joint disease with substantial mortality and morbidity. …”

A tension-independent mechanism reduces Aurora B-mediated phosphorylation upon microtubule capture by CENP-E at the kinetochore by Carmen Taveras (6731699)

“…Current models suggest that tension exerted between a pair of sister-kinetochores (inter-kinetochore stretch) produces a spatial separation of Aurora B kinase from kinetochore-associated microtubule binding substrates, such as the Knl1-Mis12-Ndc80 (KMN) network, resulting in a decrease of phosphorylation and, thus, an increase of affinity for microtubules. …”

Data_Sheet_3_Sex, Age, and Bacteria: How the Intestinal Microbiota Is Modulated in a Protandrous Hermaphrodite Fish.PDF by M. Carla Piazzon (5576864)

“…Pathway analysis performed with the inferred metagenome showed significant differences between 1-year-old males and 4-year-old females, with an increase in infection-related pathways, nitrotoluene degradation and sphingolipid metabolism, and a significant decrease in carbohydrate metabolism pathways with age. …”

Environmental dependence of the total CaCO₃ precipitated during a bloom of evolutionarily optimized coccolithophores. by Takahiro Irie (239664)

“…<p>The population-wise carbon fixation (<i>W</i>) is given as the sum of the CaCO₃ left during the bloom (<i>W</i>₁) and the CaCO₃ carried over until the end of the bloom (<i>W</i>₂). (A) Both <i>W</i>₁ (solid line) and <i>W</i>₂ (dashed line) decrease and then increase with increasing net production coefficient (<i>a</i>) with <i>s</i> = 0.001. …”

Lack of RsmA-Mediated Control Results in Constant Hypervirulence, Cell Elongation, and Hyperflagellation in <em>Pectobacterium wasabiae</em> by Viia Kõiv (276156)

“…In this study the physiological role of gene regulation by RsmA is under investigation. Disruption of <em>rsmA</em> gene of the <em>Pectobacterium wasabiae</em> strain, SCC3193 resulted in 3-fold decrease in growth rate and increased virulence. …”

Table_2_Efficacy and Safety of Empagliflozin on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.xlsx by Yuyuan Zhang (1275144)

“…Objective<p>Clinical trials have recently shown a connection between nonalcoholic fatty liver disease (NAFLD) and empagliflozin. …”

The Orally Available, Synthetic Ether Lipid Edelfosine Inhibits T Cell Proliferation and Induces a Type I Interferon Response by Pierre Abramowski (542289)

“…Low doses of edelfosine led to a decrease in homeostatic proliferation, and further studies of the mechanism/s of action by genome-wide transcriptional profiling showed that edelfosine reduces the expression of MHC class II molecules, of molecules involved in MHC class II-associated processing and presentation, and finally upregulated a series of type I interferon-associated genes. …”

Image_1_Neurotransmitter content heterogeneity within an interneuron class shapes inhibitory transmission at a central synapse.JPEG by Dimitri Dumontier (14326518)

“…We isolate a slow spillover component of GrCs inhibition that is also affected by the expression of GlyT2, leading to a 56% decrease in relative charge. …”

Table 1_A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes.docx by Cara Jeffrey (20437895)

“…It was also determined that loss of yield and a decrease in seed size was significantly correlated with high GDD and SDD, though seed size had less environmental plasticity (variability) compared to yield, and therefore higher stability under stress. …”

Synthesis, Structure, and Physical Properties for a Series of Monomeric Iron(III) Hydroxo Complexes with Varying Hydrogen-Bond Networks by Jhumpa Mukherjee (2012404)

“…Spectroscopic trends were also found, including an increase in the energy of the O−H vibrations with a decrease in the number of hydrogen bonds. However, the Fe^III/II reduction potentials were constant throughout the series (∼2.0 V vs [Cp₂Fe]^0/+1), which is ascribed to a balancing of the primary and secondary coordination-sphere effects.…”

Data_Sheet_1_How Does the Waterlogging Regime Affect Crop Yield? A Global Meta-Analysis.docx by Li-xin Tian (10167362)

“…The results suggested that waterlogging obviously decreased crop yield by 32.9% on average, compared with no waterlogging, which was a result of a reduced 1,000-grain weight (13.67%), biomass (28.89%), plant height (10.68%), net photosynthetic rate (P_n, 39.04%), and leaf area index (LAI, 22.89%). …”

GTPase activity restores the ability of GEFs to positively regulate a G protein by moving the system away from equilibrium. by Rob J. Stanley (3177219)

“…The shaded region denotes the region which is most likely to be physiologically relevant. <b>A</b> In the absence of GTPase activity, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0151861#pone.0151861.e016" target="_blank">Eq 5</a>, increasing the GEF concentration can only decrease the steady-state concentration of active G protein, instead producing GEF·G protein complexes. …”

Impact of bundle implementation on the incidence of peri/intraventricular hemorrhage among preterm infants: a pre-post interventional study by Cristiane Akemi Koyama Wallau (12800532)

“…OBJECTIVE: To evaluate the efficacy of a bundle of interventions designed to decrease the incidence of intraventricular hemorrhage at hospital discharge among preterm infants. …”

Datasheet1_Causal relationship between immunophenotypes and mitral valve prolapse: a bidirectional Mendelian randomization study.pdf by Yue Wang (65477)

“…Background<p>Emerging evidence indicates a significant link between various immune cell types and the development of heart valve disorders. …”

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models by Satish Noonepalle (7344425)

“…<i>In vivo</i> studies reveal that a combination of Suprastat and anti-PD1 immunotherapy enhances antitumor immune response, mediated by a decrease of protumoral M2 macrophages and increased infiltration of antitumor CD8+ effector and memory T-cells.…”

Table_1_Efficacy and Safety of Empagliflozin on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.docx by Yuyuan Zhang (1275144)

“…Objective<p>Clinical trials have recently shown a connection between nonalcoholic fatty liver disease (NAFLD) and empagliflozin. …”

Data_Sheet_1_Sex, Age, and Bacteria: How the Intestinal Microbiota Is Modulated in a Protandrous Hermaphrodite Fish.PDF by M. Carla Piazzon (5576864)

“…Pathway analysis performed with the inferred metagenome showed significant differences between 1-year-old males and 4-year-old females, with an increase in infection-related pathways, nitrotoluene degradation and sphingolipid metabolism, and a significant decrease in carbohydrate metabolism pathways with age. …”

Aβ-induced dispersal of Homer1b and Shank1 clusters does not depend upon protein degradation. by Francesco Roselli (211670)

“…(C) Neither proteasomal activity nor <i>de novo</i> protein synthesis were found to be necessary for Aβ-induced dispersal of Shank1 clusters. (D) Exposure to Aβ for up to 120 min. did not lead to down-regulation of Shank1 levels in whole cell protein extracts; however, a significant decrease in Shank1 was observed after 180 min of exposure to Aβ (80.7±9.7% of baseline; p<0.05). …”

Data_Sheet_1_Evolutionarily Stable Coevolution Between a Plastic Lytic Virus and Its Microbial Host.pdf by Melinda Choua (10829088)

“…Cell size, for example, is a fundamental trait for microbial hosts that can not only alter the probability of viral adsorption, but also constrain the host physiological processes that the virus relies on to replicate. …”

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models by Satish Noonepalle (7344425)

“…<i>In vivo</i> studies reveal that a combination of Suprastat and anti-PD1 immunotherapy enhances antitumor immune response, mediated by a decrease of protumoral M2 macrophages and increased infiltration of antitumor CD8+ effector and memory T-cells.…”