The Novel Gene <i>CRNDE</i> Encodes a Nuclear Peptide (CRNDEP) Which Is Overexpressed in Highly Proliferating Tissues by Lukasz Michal Szafron (740177)

“…This ORF was cloned into two expression vectors, subsequently utilized in localization studies in HeLa cells. We also developed a polyclonal antibody against CRNDEP. Its specificity was confirmed in immunohistochemical, cellular localization, Western blot and immunoprecipitation experiments, as well as by showing a statistically significant decrease of endogenous CRNDEP expression in the cells with transient shRNA-mediated knockdown of <i>CRNDE</i>. …”

DataSheet1_A drilling wellbore pressure calculation model considering the effect of gas dissolution and suspension.xlsx by Wenbo Zhang (498386)

“…During the pressure process, gas dissolution leads to an increase in the peak pressure in the wellbore and a delay in its occurrence; gas suspension leads to a decrease in the peak pressure in the wellbore and a delay in its occurrence. …”

Supplementary Material for: Association of intrauterine growth with retinopathy of prematurity risk in very preterm infants: a multicenter cohort study by figshare admin karger (2628495)

“…The incidence was 27% for any stage ROP and 3.7% for severe ROP (stage 3 or above). Each decrease of BW percentile by 10% was associated with 15% increase of odds for either any stage ROP (aOR 0.85 [95% CI 0.83-0.86]) or severe ROP (aOR 0.85 [95% CI 0.82-0.89]). …”

DataSheet6_A drilling wellbore pressure calculation model considering the effect of gas dissolution and suspension.xlsx by Wenbo Zhang (498386)

“…During the pressure process, gas dissolution leads to an increase in the peak pressure in the wellbore and a delay in its occurrence; gas suspension leads to a decrease in the peak pressure in the wellbore and a delay in its occurrence. …”

Expanding the Understanding of Biases in Development of Clinical-Grade Molecular Signatures: A Case Study in Acute Respiratory Viral Infections by Nikita I. Lytkin (218986)

“…</p> <h3>Methodology and Principal Findings</h3><p>Using a recently introduced data-analytic protocol as a case study, we provide an in-depth examination of the poorly studied biases of the data-analytic protocols related to signature multiplicity, biomarker redundancy, data preprocessing, and validation of signature reproducibility. …”

DataSheet_1_Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study.docx by Yangming Qu (6167132)

“…Multivariable MR analysis was used to identify independent risk factors. A fixed-effect model meta-analysis was used to combine the results of the FinnGen and UKB data.…”

Image_8_A Prognostic Model of Differentiated Thyroid Cancer Based on Up-Regulated Glycolysis-Related Genes.tif by Min Wu (41570)

“…</p>Conclusions<p>The GRG signature-based predictive model may help clinicians provide a prognosis for DTC patients with a high risk of recurrence after surgery and provide further personalized treatment to decrease the chance of relapse.…”

Image2_Barrier Perturbation in Porcine Peyer’s Patches by Tumor Necrosis Factor is Associated With a Dysregulation of Claudins.tif by Linda Droessler (12676895)

“…Subsequent molecular analysis of TJ protein expression revealed a marked decrease of claudin-1 and -4, and an increase of claudin-2. …”

Supplementary Material for: Positron Emission Tomography (PET) and PET/CT in Thyroid Cancer: A Systematic Review and Meta-Analysis by Schütz F. (4531018)

“…The authors showed that a positive result of PET/CT in restaging patients with differentiated thyroid cancer yielded a significant decrease in overall survival (hazard ratio, HR 5.01, CI 3.41–6.62). …”

Left Ventricular Regional Wall Motion Abnormality is a Strong Predictor of Cardiotoxicity in Breast Cancer Patients Undergoing Chemotherapy by Márcio Vinícius Lins de Barros (6099170)

“…Cardiotoxicity was defined by a 10% decrease in the left ventricular ejection fraction, on at least one echocardiogram. …”

Data_Sheet_1_Periodontal pathogens of the interdental microbiota in a 3 months pregnant population with an intact periodontium.docx by Florence Carrouel (3169617)

“…Dietary habits and physical activity did not have a significant impact on interdental microbiota, although a decrease in the median amount of 9 periodontopathogens was observed when fruit and vegetable consumption increased. …”

Table 3_Pan-cancer analysis of phagocytosis regulators in female-specific cancers: a focus on HMGB2.xlsx by Xiaoqin Lu (3121482)

“…Furthermore, when HMGB2 knockdown was combined with Palbociclib treatment, a significant decrease in tumor cell proliferation was observed across multiple cancer models.…”

Data Sheet 1_Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity.docx by Krishma Tailor (13730582)

“…We therefore sought to target IGF-1 to growth plate cartilage by generating fusion proteins combining IGF-1 with single-chain human antibody fragments that target matrilin-3, a cartilage matrix protein. We previously showed that this cartilage-targeting IGF-1 fusion protein (CV1574-1) promoted growth plate function in a GH-deficient (lit) mouse model. …”

Table 2_Cost-effectiveness of mass drug administration for control of scabies in Ethiopia: a decision-analytic model.docx by Natalia Hounsome (2833178)

“…An increase in the cost of ivermectin from 0 (donated) to 0.54 US$/dose resulted in a decrease in the probability of MDA being cost-effective from 85% to 17%. …”

Is There ‘Anther-Anther Interference’ within a Flower? Evidences from One-by-One Stamen Movement in an Insect-Pollinated Plant by Ming-Xun Ren (515126)

“…As a result, pollen removal of the dehiscing anther decreases dramatically. …”

A. The difference in mean value of AT1 measured preoperative, after lenticule creation, and after lenticule extraction during SMILE. by Yang Shen (66591)

Table_7_A Prognostic Model of Differentiated Thyroid Cancer Based on Up-Regulated Glycolysis-Related Genes.xlsx by Min Wu (41570)

“…</p>Conclusions<p>The GRG signature-based predictive model may help clinicians provide a prognosis for DTC patients with a high risk of recurrence after surgery and provide further personalized treatment to decrease the chance of relapse.…”

Table 1_Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study.docx by Katarzyna Kosinska-Kaczynska (6794522)

“…</p>Results<p>In cervico-vaginal samples, bacterial 16S rRNA gene sequencing demonstrated a decrease in alpha diversity, measured with the Shannon index, in the study group compared to the control group. …”

Effects of Ni²⁺ on mitochondrial (A), glycolytic (B), and total (C) ATP production rates in BMDM. by Jesse Corbin (21736578)

“…A double dagger (‡) indicates a significant decrease of mitochondrial ATP production rates (slope = −0.79 ± 0.21, <i>R</i>^<i>2</i> = 0.40, <i>F</i>(1, 22)=15.0, <i>p </i>< 0.001) from 0 to 72 ppm Ni²⁺. …”

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation by Arlene I. Ramsingh (361967)

“…Here, we test the hypothesis that immunomodulation by rapamycin can decrease immune reactivity after intrathecal AAV9 delivery of a transgene (GFP) in non-human primates, resulting in sustained GFP expression in the CNS. …”