siRNA oligonucleotide specific for PKA causes decreased expression and activity of PKA and ameliorated the high glucose mediated decrease of G6PD activity. by Zhaoyun Zhang (118032)

“…Figures A and B show that siRNA led to decreased expression and decreased activity of PKA. …”

Overexpression of cyclin D-CDK complex components rescues AR-mediated growth suppression of HPr-1AR. by Young-Chae Kim (163381)

“…<p>(A) Transient overexpression of cyclin D1 and cyclin D2 was validated by immunoblot analysis. …”

SERCA2A expression is regulated by mTORC2. by Angelika Kusch (368579)

“…<p>Rictor silencing was induced by cell transfection with rictor siRNA and then, cells were stimulated with IGF-1 for 24 hours in presence or absence of E2. mTORC2 downregulation was confirmed by abolished Akt-pS473 and resulted in decreased SERCA2A protein expression. Akt-pT308, mTOR and raptor were not negatively affected by rictor silencing. …”

17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling by Angelika Kusch (368579)

“…In addition, cardiomyocytes with reduced Akt-pS473 under rapamycin treatment displayed decreased SERCA2A mRNA and protein expression suggesting negative functional consequences on cardiomyocyte contractility. …”

IL-17A, a possible biomarker for the evaluation of treatment response in <i>Trypanosoma cruzi</i> infected children: A 12-months follow-up study in Bolivia by Clara Vásquez Velásquez (7429844)

“…</p><p>Within 14 Th1/Th2/Th17 cytokines, IL-17A showed significantly higher levels in seropositive children before the treatment compared to age-matched seronegative children and significantly decreased to the normal level one-year after. …”

Body distribution of <i>P</i>. <i>mirabilis</i> in tumor-bearing mice. by Hong Zhang (25820)

“…<p>(A) The bacteria were detected in tumors and other organs, including heart, liver, spleen, lung and kidney at 0, 6, 24, 48, 72, and 96 hours after <i>P</i>. …”

The therapeutic effect of <i>P</i>. <i>mirabilis</i> in 4T1 solid tumor model. by Hong Zhang (25820)

“…<p>(A) Bacterial treatment suppressed tumor growth at the end of the experiment. …”

siRNA knockdown of TGFβ1 in NTM cells led to an increase in RASAL1 expression by Western blotting. by Fiona McDonnell (2636635)

“…This indicates that when TGFβ1 is decreased, its pathway is also affected. Further, a decrease in TGFβ1 expression by siRNA treatment also led to an increase in RASAL1 protein expression B, a decrease in COL1A1 expression C and a decrease in DNMT1 expression D. …”

Effects of busulfan treatment (6 mg/kg) on the epididymis and sperm of mice over a three-week period. by Lingjun Zhao (21763122)

“…<p>(A) The epididymal sperm concentrations decrease over time and significantly differ between hour 0 (control) and day 21 (<i>n </i>= 3 per group). …”

High ELS participants exhibited lower positive feedback sensitivity than those without a history of ELS. by Matthew Paul Wilkinson (11824625)

Image_1_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_5_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_3_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.tif by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_6_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_2_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_4_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.tif by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Model for AR-mediated growth suppression of HPr-1AR and PC3-Lenti-AR. by Young-Chae Kim (163381)

“…(B) Androgen signaling through AR increases CDKN1A expression and decreases the abundance and activity of cyclin D-CDK4/6 complexes by multiple mechanisms. …”

The Efficacy of Taurolidine Lock Solution in Preventing Catheter-Related Bloodstream Infections in Pediatrics: A Systematic Review and Meta-Analysis by Congyu Qin (22386781)

Motor Adaptations to Pain during a Bilateral Plantarflexion Task: Does the Cost of Using the Non-Painful Limb Matter? by François Hug (290603)

“…This decrease in force was correlated with a decrease in drive to the soleus muscle. …”

Discrimination between Adenocarcinoma and Normal Pancreatic Ductal Fluid by Proteomic and Glycomic Analysis by Mindy Porterfield (1849300)

“…Our results identify a set of seven proteins that were consistently increased in cancer ductal fluid compared to normal (AMYP, PRSS1, GP2-1, CCDC132, REG1A, REG1B, and REG3A) and one protein that was consistently decreased (LIPR2). …”