FACS Analysis of TEC profile and quantification of TEC numbers in response to DKK1 mediated inhibition of Wnt signaling. by Masako Osada (253586)

“…CD45 magnetic beads were used to partially deplete CD45⁺ hematopoietic cells from the resulting single cell suspension, prior to staining with antibodies against CD45, MHCII, EpCAM, and CD80 together with UEA1 lectin. TetO-Dkk1 mice showed a dramatic decrease in the frequency of EpCAM⁺ MHCII⁺ CD45⁻ TECs (<b>A</b>, upper left) when compared with K5rtTA-ST controls (<b>A</b>, upper right panel). …”

VOR baseline and adaptation. by Giorgio Grasselli (217929)

“…<p>(A) Compensatory eye movements, aimed at minimizing retinal slip caused by visual and/or vestibular input, were used to test motor performance in L7-SK2 mice. …”

Data_Sheet_1_Modifications of the PI3K/Akt/mTOR axis during FeHV-1 infection in permissive cells.PDF by Gianmarco Ferrara (12673317)

“…In addition, we found an early phosphorylation of Akt, approximately 3 h after infection, without a concomitant decrease in constitutive Akt. This result suggests a possible role for this axis in viral entry. …”

Sample details and genome coverage (n = 1,409). by Mathieu Vanhove (3298326)

“…In the five-year study period, we observed a decrease in frequency of a mutation associated with artemisinin partner drug (piperaquine) resistance (<i>pfcrt</i> C350R) and limited co-occurence of <i>pfcrt</i> C350R with duplications of <i>plasmepsin 2/3</i>, an epistatic interaction associated with piperaquine resistance. …”

The human T-cell development is altered in HTLV-1-infected HIS Rag2^-/-γ_c^-/- mice. by Julien Villaudy (40472)

“…(<b>B</b>) Composite data from 20 HTLV-1-infected mice with a low PVL and 15 HTLV-1-infected mice with a high PVL showing a decrease in the frequency of the immature thymocytes (light grey) concomitant with an increase of that of the mature SP cells (black) in high PVL mice. …”

Data_Sheet_1_Isolation and identification of ligninolytic bacterium (Bacillus cereus) from buffalo (Bubalus bubalis) rumen and its effects on the fermentation quality, nutrient com... by Huimin Zhong (6847475)

“…The B. cereus AH7-7 additive treatments reduced the bacterial diversity and optimized the bacterial community compositions of silage, with an increase in the relative abundance of beneficial Lactobacillus and a decrease in the relative abundance of undesirable Pantoea and Erwinia. …”

DataSheet1_FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway.docx by Shike Yan (777488)

“…Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been used as a first-line treatment for patients harboring with EGFR mutations in advanced NSCLC. …”

Improvement of insulin sensitivity in diabetic and non diabetic patients with chronic hepatitis C treated with direct antiviral agents by Alessandro Gualerzi (6107468)

“…At the end of treatment, HCV-RNA quantification was below the detection threshold (HCV-RNA <12 UI/ml), for all patients enrolled. A significant decrease in glucose and insulin plasma concentrations was observed, leading to a significant reduction in Homeostasis Model Assessment (HOMA)-IR (from 3.42 [2.66–5.38] to 2.80 [1.78–3.95];p<0.001) and a corresponding increase in insulin sensitivity (ISI Belfiore from 0.49 [0.26–0.75] to 0.64 [0.42–0.91];p<0.001), despite a significant reduction in insulin secretion (EFP Stumvoll from 1363 [959–1730] to 1264 [976–1588];p = 0.027). …”

DataSheet_1_Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant... by Ju Zeng (3426107)

“…<p>Aging is a natural biological process associated with cognitive decline and neuroendocrine–immune system changes; the neuroendocrine–immune system plays crucial role in brain aging and neurodegeneration, and it is essential to discern beneficial attempts to delay the aging progress based on immunological aging. …”

Hyperbaric oxygen therapy and comprehensive orthopedic treatment for incomplete traumatic spinal cord injury on the Qinghai-Tibet Plateau: study protocol for an open-label randomiz... by Jun Ma (4058161)

“…<div>Background: Apoptosis secondary to ischemia and hypoxia is the main cause of spinal cord dysfunction. Because of the decrease in atmospheric pressure, patients living on the Qinghai-Tibet Plateau are in a hypoxic environment, which is very unfavorable for the recovery of spinal cord injury. …”

Table_8_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.xls by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Number of possible positive roots of . by Temesgen Debas Awoke (18291050)

“…Moreover, applying a maximum of 15% additional effort to reduce the number of vectors, decreases the total VL prevalence by 57.71%. …”

Table_1_Analysis of an Imported Subgenotype C2 Strain of Human Enterovirus 71 in Beijing, China, 2015.DOCX by Jie Li (15030)

“…</p><p>Conclusion: This is the first report of an EV71 subgenotype C2 isolated from HFMD in Beijing, China. Only a few antigenic variations on subgenotype C2 of EV71 could have led to a great decrease in NTAb titer. …”

Table_7_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.xlsx by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Data_Sheet_1_Insightful Backbone Modifications Preventing Proteolytic Degradation of Neurotensin Analogs Improve NTS1-Induced Protective Hypothermia.docx by Santo Previti (4350607)

“…Neurotensin (NT), which exerts its effects through activation of two G protein-coupled receptors, namely NTS1 and NTS2, induces a strong and long-lasting decrease in core body temperature after its central administration. …”

The Biodiversity of the Mediterranean Sea: Estimates, Patterns, and Threats by Marta Coll (213022)

“…Spatial patterns showed a general decrease in biodiversity from northwestern to southeastern regions following a gradient of production, with some exceptions and caution due to gaps in our knowledge of the biota along the southern and eastern rims. …”

Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells by Cecilia Morell (729630)

“…On the other hand, LAMP2 knockdown by siRNA led to a marked blockage of autophagy, prevention of NE differentiation and decrease of cell survival. …”

Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts by Kristine Yttersian Sletta (4386352)

“…</p><p>Results</p><p>HBOT significantly suppressed tumor growth in both the triple positive and negative tumors, and both MDA-MB-231 and BT-474 showed a decrease in proliferation after HBOT. No differences were found in angiogenesis or 5FU efficacy between HBOT and controls. …”

Table_1_Lyme borreliosis in pregnancy and associations with parent and offspring health outcomes: An international cross-sectional survey.PDF by Katherine Leavey (697697)

“…Background<p>Lyme disease (LD) is a complex tick-borne pathology caused by Borrelia burgdorferi sensu lato bacteria. …”

Fe- and Ln-DOTAm-F12 Are Effective Paramagnetic Fluorine Contrast Agents for MRI in Water and Blood by Kriti Srivastava (2231482)

“…This increased sensitivity is due to a substantialup to 100-folddecrease in the longitudinal relaxation time (<i>T</i>₁) of the fluorine nuclei. …”