DataSheet1_Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation... by Eldiza Puji Rahmi (8584506)

“…In the XO inhibitory activity, none of the samples exhibited greater than 50% inhibition. However, in a rat model, EtOH80 extract (200 mg/kg/day) and andrographolide (30 mg/kg/day) decreased serum uric acid levels and reduced liver XO activity, reduced the protein expression levels of URAT1 and GLUT9, and restored the decrease in OAT1 levels. …”

DataSheet_1_Changes in HCMV immune cell frequency and phenotype are associated with chronic lung allograft dysfunction.pdf by Amélie Rousselière (14201600)

“…Immunophenotype reveals an altered expression profile for HLA-EUL40 CD8 T in CLAD patients with a decreased expression for CD56 and the acquisition of PD-1. …”

Image_1_Changes in HCMV immune cell frequency and phenotype are associated with chronic lung allograft dysfunction.jpeg by Amélie Rousselière (14201600)

“…Immunophenotype reveals an altered expression profile for HLA-EUL40 CD8 T in CLAD patients with a decreased expression for CD56 and the acquisition of PD-1. …”

<i>Mybl2</i> gene products are abundant in pluripotent stem cells and are dynamically regulated during differentiation. by Kirill V. Tarasov (75912)

“…<p>A) Representative immunostainings of pre-implantation mouse blastocysts. …”

Image 2_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy donor... by Julie Stichova (19729855)

“…However, in both cohorts were individuals (HDs: 35/49, AEA: 40/58) who responded to calcitriol with a more pronounced regulatory response. The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4⁺ T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”

Data_Sheet_1_Long COVID outcomes following omicron wave in non-hospital population.PDF by Wang Ruiyin (18157636)

“…Male and those possessing advanced educational qualifications exhibit a decreased susceptibility to the sustained incidence of coughing. …”

Laryngeal Elevation Velocity and Aspiration in Acute Ischemic Stroke Patients by Jing Zhang (23775)

“…This may be related to a decreased contraction velocity of the muscles involved in hyolaryngeal elevation. …”

Data Sheet 1_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy... by Julie Stichova (19729855)

“…However, in both cohorts were individuals (HDs: 35/49, AEA: 40/58) who responded to calcitriol with a more pronounced regulatory response. The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4⁺ T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”

Primary and secondary outcomes. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Budget impact of suzetrigine for the treatment of moderate-to-severe acute pain in Medicaid-insured adults by Kenna Garrison (22820311)

“…Use of suzetrigine led to a reduction in the number of patients using opioids and a corresponding decrease in the number of patients who experience OUD/opioid abuse or nausea/vomiting. …”

European study sites. by Graeme T. Swindles (7192745)

“…We also note that the highest values of aPAR are found when the water table is within 5–10 cm of the peatland surface. aPAR is generally low when water table depths are < 0 cm (standing water) or > 25 cm, which may relate to a decrease in plant productivity and increased decomposition losses, respectively. …”

Supplementary Material for: Physical Activity, Screen Time, and Sleep Duration of Children Aged 6–9 Years in 25 Countries: An Analysis within the WHO European Childhood Obesity Sur... by Whiting S. (9907584)

“…<b><i>Method:</i></b> The fourth COSI data collection round was conducted in 2015–2017, using a standardized protocol that included a family form completed by parents with specific questions about their children’s PA, screen time, and sleep duration. …”

Safety outcomes. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Location of study sites. by Graeme T. Swindles (7192745)

“…We also note that the highest values of aPAR are found when the water table is within 5–10 cm of the peatland surface. aPAR is generally low when water table depths are < 0 cm (standing water) or > 25 cm, which may relate to a decrease in plant productivity and increased decomposition losses, respectively. …”

HeLa (Cilengitide treatment or MBCD treatment) PREM membrane images supporting "The structure and spontaneous curvature of clathrin lattices at the plasma membrane" by Kem Sochacki (10280270)

“…<br><div><br></div><div>HeLa cells were treated with drugs to remove cholesterol (methyl-β-cyclodextrin) or block the binding of aVB5 integrin (Cilengitide). Removing cholesterol caused an increase in flat clathrin while blocking integrins caused a decrease in flat clathrin. …”

Lack of decoration of <i>L</i>. <i>infantum</i> LEM 5700 parasites with lysosome-associated hydrolase cathepsin, hexose transporter GLUT8, and polypeptide transporter TAPL in macro... by Sandrine Cojean (274005)

“…<p><b>(A)</b> 3D-reconstruction surface rendering confocal micrograph showing the absence of decoration of fusiform-like and ellipsoidal parasite forms with GLUT8-positive patches in a Retro-2 (1 μM)-treated cell. …”

Transition-Metal Carbonyl Complexes of 2,5-Diferrocenyl-1-phenyl‑1<i>H</i>‑phosphole by Dominique Miesel (1533022)

“…However, the coordination of the dienic system in <b>9</b> results in a significantly decreased electronic communication of the Fc/Fc⁺ termini via the heterocyclic core.…”

COMMD1 mediates aggregation of ALS-associated SOD1 mutants. by Willianne I. M. Vonk (191330)

“…EV, SOD1 WT and mSOD1 D90A values were considered as 0 as these proteins do not form aggregates. * indicates significantly decrease in mSOD1 aggregation upon COMMD1 knock-down (* p<0.05, ** p<0.005, **** p<0.0001). n.s…”

Enrolment, randomisation, and follow-up. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Cystic Fibrosis Transmembrane Conductance Regulator Attenuates Oxidative Stress-Induced Injury in Diabetic Retinopathy Rats by Hui Wang (30400)

“…</p> <p>CFTR can inhibit MAPK/NF-κB signaling pathway to ameliorate inflammatory response and oxidative stress-induced injury of DR rats, thereby reducing retinal cell apoptosis and playing a protective role in retina.</p>…”