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50341
Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors
Published 2018“…Monoacylglycerol lipase (MAGL) is a major serine hydrolase that hydrolyzes 2-arachidonoylglycerol (2-AG) to arachidonic acid (AA) and glycerol in the brain. …”
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50342
Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
Published 2016“…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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50343
Image_2_Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.JPEG
Published 2021“…<p>Schizophrenia (SCZ) is a chronic and severe mental disease that affects around 1% of the population. …”
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50344
HuR specifically represses translation through the IGF-IR 5′-UTR in a concentration-dependent manner
Published 2011“…The FLuc RNA (5 ng) was used as a control. The results are expressed relative to the control reactions without HuR. () translation with recombinant HuR protein. …”
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50345
Deletion of <i>Kif3a</i> in early stages of forebrain development leads to increased brain size.
Published 2017“…<p>(A-L) <i>Foxg1-Cre</i> was used to delete a conditional allele of <i>Kif3a</i> and the forebrain was enlarged at E14.5 (B) and E18.5 (H,J,). …”
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50346
Image_1_Case report: A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome.tif
Published 2023“…HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. …”
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50347
DataSheet1_Learning the Quantum Centroid Force Correction in Molecular Systems: A Localized Approach.docx
Published 2022“…<p>Molecular mechanics (MM) is a powerful tool to study the properties of molecular systems in the fields of biology and materials science. …”
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50348
Image_2_Case report: A case of sepsis caused by rickettsial infection-induced hemophagocytic syndrome.tif
Published 2023“…HLH encompasses a group of clinical syndromes marked by the overproduction of inflammatory cytokines. …”
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50349
Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx
Published 2025“…<p>Malignant melanoma ranks among the most aggressive forms of cancer, with high rates of metastasis and recurrence, as well as a poor prognosis. Consequently, an urgent need is to develop novel precision therapeutic strategies and corresponding drugs. …”
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50350
CCK activation of primary vagal afferents is blocked by CCK analog JMV-180 (JMV) across species. A)
Published 2013“…<b>C</b>) JMV significantly decreased CCK-induced calcium influx in a reversible manner. …”
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50351
Quantification of Fiber Shedding from Cotton Fabrics During Drying in a Domestic Heat Pump Tumble Dryer
Published 2024“…In the last phase, the rate of fiber accumulation decreased. The experiments also showed that longer tumbling of textiles with a lower moisture content led to a greater total mass of accumulated fibers. …”
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50352
Supplementary Material for: Innovative regenerative treatment with Nanofat injection for hypertensive ischemic leg ulcer: a case report
Published 2025“…The regenerative potential of Nanofat, derived from adipose tissue, offers a promising therapeutic option. Case Presentation: We describe a 75-year-old female patient with a chronic ischemic ulcer measuring 30.1 cm² and persisting for more than 5 years. …”
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50353
Data_Sheet_1_Efficacy of repetitive transcranial magnetic stimulation on chronic migraine: A meta-analysis.pdf
Published 2022“…Introduction<p>Migraine is a neurovascular disorder that affects the quality of life of more than 1 billion people worldwide. …”
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50354
Additional dataset for "Pump and sway: wild primates use compliant supports as a tool to augment leaping in the canopy"
Published 2023“…This deliberate branch manipulation to produce a mechanical effect for stronger propulsion fits into the framework of instrumental problem-solving. …”
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50355
Image_6_Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.JPEG
Published 2021“…<p>Schizophrenia (SCZ) is a chronic and severe mental disease that affects around 1% of the population. …”
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50356
[Reproductive potential of Nelore bulls evaluated by andrological parameters and sexual behavior. Classification by points - a new proposition]
Published 2021“…<p></p><p>ABSTRACT This study aimed to compare variations of andrological and behavioral parameters from Nelore bulls of different ages, to calculate their reproductive potential (RP) and propose a new classification table by points, considering current averages in each reproductive trait studied. …”
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50357
Image_3_Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.JPEG
Published 2021“…<p>Schizophrenia (SCZ) is a chronic and severe mental disease that affects around 1% of the population. …”
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50358
Effect of bilirubin on measurements of ADAMTS13 activity using XS-VWF and A2-77p-long.
Published 2015“…Baseline FRET ratio at <i>t</i> = 0s decreased upon increasing bilirubin dose. <b>B.</b> XS-VWF samples obtained at 60min. in panel A were analyzed using western blots and anti-tetra His antibody to detect the ~36kDa substrate cleavage band. …”
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50359
Changes in mineral nutrition during fruit growth and development of ‘Seike’ and ‘Newhall’ navel orange as a guide for fertilization
Published 2019“…During these accumulation periods, it is recommended that suitable fertilizers be applied in a timely manner.</p></div>…”
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50360
Euphorbia kansui reactivates HIV in a model of HIV latency using resting human CD4+ T cells.
Published 2016“…<p>(a) Human primary CD4+ T cells were activated and expanded with CD3/CD28 beads and 30 U IL-2/ml for 7 days. …”