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linear decrease » linear increase (Expand Search)
latest decrease » largest decrease (Expand Search), greatest decrease (Expand Search), largest decreases (Expand Search)
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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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10741
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10742
S1A Fig raw image.
Published 2025“…Here, we identify cathepsin Z (<i><i>Ctsz</i></i>) as a lead candidate underlying this TB susceptibility and show that <i><i>Ctsz</i></i> ablation leads to increased bacterial burden, pulmonary inflammation and decreased survival in mice. …”
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10743
Behavioural data from Study A.
Published 2024“…In addition, human walking positively influenced eye contact behaviour while simultaneously decreasing exploration behaviour. In study C, a group of six socialised pack-living wolves and six similarly socialised pack-living dogs were tested after the <i>Ignore</i> treatment. …”
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10744
Establishment of a diabetic rat model.
Published 2025“…In addition, RP11-502I4.3 expression was decreased in the retinas of diabetic rats compared with non-diabetic rats (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312791#pone.0312791.g003" target="_blank">Fig 3B</a>), and it was predominantly localised in the cytoplasm (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312791#pone.0312791.g003" target="_blank">Fig 3C</a>).…”
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10745
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10746
S4 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10747
S1 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10748
S5 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10749
S3 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10750
S6 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10751
Input parameters for the base-case analysis.
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10752
S2 Fig -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10753
S1 Data -
Published 2024“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”
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10754
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10755
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10756
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10757
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10758
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10759
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10760