Data_Sheet_1_Low molecular weight heparin decreases mortality and major complication rates in moderately severe and severe acute pancreatitis–a systematic review and meta-analysis.docx by Cristina Patoni (16619856)

“…Randomized controlled trials (RCTs) and observational studies that reported the differences in the outcomes of AP for patients receiving anticoagulants (intervention group) in addition to the standard of care (SOC), compared to patients managed by SOC alone (control group), were eligible. A random-effects model was used to calculate the pooled odds ratios (OR) and mean differences (MD) with the corresponding 95%-confidence intervals (CI). …”

Decreased intracellular replication of <i>S</i>. Typhimurium Δ<i>sucCD</i> and Δ<i>gltA</i> strains during infection of HeLa epithelial cells. by Steven D. Bowden (237943)

Evolutionary dynamics of replicators’ association rate without and with parasites: <i>k</i>_<i>a</i> decreases in the absence of parasites, and evolves to higher values the stronger the parasites. by Enrico Sandro Colizzi (2633266)

Table_1_YTHDF2 Gene rs3738067 A>G Polymorphism Decreases Neuroblastoma Risk in Chinese Children: Evidence From an Eight-Center Case-Control Study.DOC by Huijuan Zeng (6637514)

“…We found that the rs3738067 A>G could decrease neuroblastoma risk [AG vs. AA: adjusted odds ratio (OR) = 0.76, 95% confidence interval (CI) = 0.64–0.90, P = 0.002; AG/GG vs. …”

DataSheet1_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.PDF by Sunil Veeravalli (5074115)

“…Short- and long-term treatment of wild-type mice with a 2,3-butanediol isomer mix decreased plasma cholesterol and epididymal fat deposition but had no effect on plasma concentrations of glucose or insulin, or on body weight. …”

Identification of a Novel Protein Phosphatase 2A Activator, PPA24, as a Potential Therapeutic for FOLFOX-Resistant Colorectal Cancer by Hannah Johnson (1342596)

“…A series of compounds were designed utilizing molecular modeling and fragment-based design based upon the known protein phosphatase 2A (PP2A) activators, <b>NSC49L</b> and <b>iHAP1</b>, and evaluated for their ability to inhibit the viability of colorectal cancer (CRC) and folinic acid, 5-fluorouracil, and oxaliplatin (FOLFOX)-resistant CRC cells. …”

Phenotypic diversity and drug susceptibility of <i>Trypanosoma cruzi</i> TcV clinical isolates by Luz P. Quebrada Palacio (613253)

“…Benznidazole-resistant BOL-FC10A epimastigotes had decreased expression of Old Yellow Enzyme and cytosolic superoxide dismutase, and overexpression of mitochondrial superoxide dismutase and tryparedoxin- 1, compared to benznidazole-susceptible AR-SE23C parasites. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

Proteomic Analysis of the Murine Liver in Response to a Combined Exposure to Psychological Stress and 7,12-Dimethylbenz(a)anthracene by Melanie S. Flint (2263015)

“…The proteomic results further indicate that exposure to DMBA induces increases in the abundance of CYP1A2 and serine protease inhibitors and decreases the abundance of CYP4 V3. …”

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven <i>Salmonella</i> Typhimurium Host Cell Invasion - Fig 2 by Daniel Andritschke (149523)

“…(H) KEGG pathway mapping of decreasing hits from the Qiagen unpooled <i>S</i>. Tm^SipA siRNA screen. …”

The phosphorylation of FgHapX mediated by the Ser/Thr kinase FgYak1 is required for the transcriptional activity of FgHapX. by Zhihui Wang (88248)

“…<p>(A) The mutations of FgHapX at 245 and 338 from Ser to Ala or loss of FgYak1 led to a decreased phosphorylation level of FgHapX. …”

The extreme N-terminus of TDP-43 is required to repress <i>UNC13A</i> cryptic exon splicing. by Yuka Koike (2249959)

“…Blot provided in Supporting information (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002028#pbio.3002028.s013" target="_blank">S1 Raw images</a>). qRT-PCR (right) analysis shows significantly decreased TDP-43 binding to <i>UNC13A</i> RNA only in the cells expressing GFP-TDP-43_5FL compared with the cells expressing GFP-TDP-43_WT. …”

PXT3003 therapy acting on Pmp22 overexpression and downstream signalling in long-term at 12 weeks. by Thomas Prukop (6236186)

“…At the end of long-term observation, PXT3003 early short-term treatment restored the decreased p-AKT/AKT signalling in CMT1A rats (H; WT controls 1.00±0.17, CMT1A controls 0.38±0.08, CMT PXT3003-3 0.93±0.21) and dose-dependently corrected the disrupted ratio of p-AKT/AKT to p-MAPK/MAPK signalling towards the wildtype situation (I; CMT1A controls 0.30±0.08, CMT PXT3003-1 0.56±0.15, CMT PXT3003-2 0.85±0.13, CMT PXT3003-3 1.36±0.52), which is characterized by a higher relative amount of p-AKT versus p-MAPK. …”

A. Concise demographic details for each patient included in the study. by Neil K. Jairath (13237338)

Immunoblotting analysis to validate the protein expression shown in Figs 1A, 2A, 4A, 4E, 5B, and S13. by Yongle Zhang (11355546)

Hypothesis 3: The mean difference between “Class 1” (a school attack happens within <i>k</i> kms. of a given school) and “Class 0” (no school attack happens within <i>k</i> kms. of a given school) for increases as the Socioeconomic Risk Score of the region of each school decreases (i.e. the school is in a wealthier neighborhood). by Lirika Sola (21560710)

Strain regimes created by bilateral activation of each of the major masticatory muscle groups during right sided chew in model A1, with a fully patent metopic suture. by Pranav N. Haravu (14043109)

Recombinant Wnt5a reduces migration. by Martin Crozier (13804275)

Table_3_The Immediate Effects of a Dynamic Orthosis on Gait Patterns in Children With Unilateral Spastic Cerebral Palsy: A Kinematic Analysis.docx by Elisabete Martins (746030)

“…Significant improvements were observed at the hip joint of both lower limbs during most of the gait cycle in participants wearing a Therasuit, including a decrease in the flexion pattern at the initial contact and swing phase in both lower limbs, and an increase in the extension pattern in the paretic lower limb during the stance phase. …”