Image_1_Regional spinal cord volumes and pain profiles in AQP4-IgG + NMOSD and MOGAD.TIFF by Susanna Asseyer (5705573)

“…Meanwhile, GM% decreased by 1–2% in two MOGAD patients with a myelitis attack between MRI visits.…”

The involvement of trimolecular complex components in the process of tumor cell transendothelial migration. by Evelyn B. Voura (475793)

“…(E) Recombinant furin convertase (rFurin; 71 U/mL) stimulated transendothelial migration of MDA-MB231 (gray bar) and WM239 (white bars) cells at 3 hours. Increasing amounts of a furin inhibiting peptide decreased WM239 transendothelial migration. …”

Table_1_Regional spinal cord volumes and pain profiles in AQP4-IgG + NMOSD and MOGAD.pdf by Susanna Asseyer (5705573)

“…Meanwhile, GM% decreased by 1–2% in two MOGAD patients with a myelitis attack between MRI visits.…”

Effects of G protein association and cellular cholesterol on CCK-8 binding and biological activity. by Jesse I. Mobbs (10925173)

“…With high cholesterol, there is increased Gs-mediated and decreased Gq/11-mediated signalling. (<b>I</b>) Quantitative pharmacology analysis of the data in panels A–G. …”

Video_1_Effect of Dry Eye Disease on the Kinetics of Lacrimal Gland Dendritic Cells as Visualized by Intravital Multi-Photon Microscopy.mp4 by Gustavo Ortiz (8484984)

“…<p>The lacrimal gland (LG) is the main source of the tear film aqueous layer and its dysfunction results in dry eye disease (DED), a chronic immune-mediated disorder of the ocular surface. …”

Data_Sheet_1_Effect of Dry Eye Disease on the Kinetics of Lacrimal Gland Dendritic Cells as Visualized by Intravital Multi-Photon Microscopy.zip by Gustavo Ortiz (8484984)

“…<p>The lacrimal gland (LG) is the main source of the tear film aqueous layer and its dysfunction results in dry eye disease (DED), a chronic immune-mediated disorder of the ocular surface. …”

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…In the same period, PUV increased in central Europe, eastern Europe, and central Asia by 116·1% (8·0–218·2). Our forecasts predict a continued global decline in HIV incidence and mortality, with the number of people living with HIV peaking at 44·4 million (40·7–49·8) by 2039, followed by a gradual decrease. …”
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Image_3_Cerebral Microbleeds, Cerebrospinal Fluid, and Neuroimaging Markers in Clinical Subtypes of Alzheimer's Disease.TIF by Masaki Ikeda (397115)

“…We then examined the levels of cerebrospinal fluid (CSF) biomarkers [Aβ1-42, Aβ1-40, Aβ1-38, phosphorylated tau 181 (P-Tau), total tau (T-Tau), neurofilament light chain (NFL), and chitinase 3-like 1 protein (YKL-40)], analyzed the number and localization of CMBs, and measured the cerebral blood flow (CBF) volume by ^99mTc-ethyl cysteinate dimer single photon emission computerized tomography (^99mTc ECD-SPECT), as well as the mean cortical standard uptake value ratio by ¹¹C-labeled Pittsburgh Compound B-positron emission tomography (¹¹C PiB-PET). …”

Image_2_Cerebral Microbleeds, Cerebrospinal Fluid, and Neuroimaging Markers in Clinical Subtypes of Alzheimer's Disease.TIF by Masaki Ikeda (397115)

“…We then examined the levels of cerebrospinal fluid (CSF) biomarkers [Aβ1-42, Aβ1-40, Aβ1-38, phosphorylated tau 181 (P-Tau), total tau (T-Tau), neurofilament light chain (NFL), and chitinase 3-like 1 protein (YKL-40)], analyzed the number and localization of CMBs, and measured the cerebral blood flow (CBF) volume by ^99mTc-ethyl cysteinate dimer single photon emission computerized tomography (^99mTc ECD-SPECT), as well as the mean cortical standard uptake value ratio by ¹¹C-labeled Pittsburgh Compound B-positron emission tomography (¹¹C PiB-PET). …”

Image_1_Cerebral Microbleeds, Cerebrospinal Fluid, and Neuroimaging Markers in Clinical Subtypes of Alzheimer's Disease.TIF by Masaki Ikeda (397115)

“…We then examined the levels of cerebrospinal fluid (CSF) biomarkers [Aβ1-42, Aβ1-40, Aβ1-38, phosphorylated tau 181 (P-Tau), total tau (T-Tau), neurofilament light chain (NFL), and chitinase 3-like 1 protein (YKL-40)], analyzed the number and localization of CMBs, and measured the cerebral blood flow (CBF) volume by ^99mTc-ethyl cysteinate dimer single photon emission computerized tomography (^99mTc ECD-SPECT), as well as the mean cortical standard uptake value ratio by ¹¹C-labeled Pittsburgh Compound B-positron emission tomography (¹¹C PiB-PET). …”

<i>eipr-1</i> mutants have defects in trafficking dense-core vesicle cargos. by Irini Topalidou (2794261)

“…<p>(A) Left: representative images of NLP-21::Venus (<i>nuIs183</i> transgene) fluorescence in motor neuron axons of the dorsal nerve cord. …”

Bacterial PAMPs (LPS) and cytokines (IFNγ) increase macrophage phagocytosis and cell elasticity. by Naimish R. Patel (136156)

“…</b> Macrophage elasticity is decreased by actin polymerization inhibitor. Optical Magnetic Twisting Cytometry (OMTC) measurement of RAW macrophages cultured on more rigid (150 kPa) surface and treated with the myosin inhibitor blebbistatin (Bleb, 50 µM) or the actin polymerization inhibitor latrunculin A (Lat A, 1 µM). …”

Neurotensin activates orexin neurons. by Naoki Furutani (169799)

“…Neurons were current-clamped and the current was stepped from –240 pA to +280 pA (with increments of 40 pA with a duration of 100 ms). …”

Table_1_Multiparametric MRI enables for differentiation of different degrees of malignancy in two murine models of breast cancer.docx by Mirjam Gerwing (7365833)

“…A decreasing accumulation of gadolinium during tumor progression was also visible in both models in LA-ICP-MS. …”

Back-propagating APs produce robust ΔCa²⁺ in distal dendrites of the NRT neurons. by Patrick Chausson (449010)

“…<p>A. Top traces: ΔCa²⁺ recorded in response to a somatically evoked burst of 45 APs at 10 Hz (left trace). …”

DataSheet1_Evaluation of Potential Herb-Drug Interactions Between Shengmai Injection and Losartan Potassium in Rat and In Vitro.PDF by Zhenchao Niu (12253952)

“…SMI affected the pharmacokinetic properties of LOS by decreasing the elimination of LOS. These effects might partly be attributed to the inhibition of the activities of CYP3A4, CYP2C9, and of the drug transporters (P-gp, BCRP, and OATP1B1) by SMI, which need further scrutiny.…”

Mapping the shape and steepness of gradients of transcription factor expression in 3D. by Matthew French (13007466)

“…Solid lines indicate the fit of a non-parametric multiple regression curve and shading indicates 0.05–0.95 confidence intervals calculated as (mean ± 1.96 * (<i>σ</i>/(√<i>n</i>)). …”

MUS81 causes DNA double-strand breaks upon Chk1 inhibition that result in cell death. by Josep V. Forment (119177)

“…<p><i>A.</i> AZD7762 treatment produces γH2AX in replicating cells. …”

IL6/STAT3 modulates estrogen-induced GREB1 transcriptional activity in breast cancer cells. by Mingli Liu (304361)

“…The samples were treated with E2 as indicated before assaying for luciferase activity. As shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046410#pone-0046410-g005" target="_blank">Figure 5G</a>, STAT3-C decreases GREB1 transcription by approximately 39%. …”

Table_2_17β-Estradiol Attenuates Neuropathic Pain Caused by Spared Nerve Injury by Upregulating CIC-3 in the Dorsal Root Ganglion of Ovariectomized Rats.XLSX by Zhen-Zhen Xu (2126308)

“…<p>17β-estradiol plays a role in pain sensitivity, analgesic drug efficacy, and neuropathic pain prevalence, but the underlying mechanisms remain unclear. …”