Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma by Marianna Carrabotta (8193039)

“…Trabectedin can impair HMGA2 activity by preventing its binding to promoters, thus inhibiting the transcription of its targets <i>IGF2BP2</i> and <i>IGF2BP3</i> and decreasing IGF2/IGF1R signaling. NVP-BEZ235 is a dual PI3K/mTOR inhibitor used in phase II clinical trials. …”

Inhibition of glucose-dependent increased CAPER protein expression suppresses cell proliferation and induces autophagy-mediated vacuolization. by Yun Kyoung Kang (715990)

“…Inhibition of CAPER expression suppresses glucose-dependent cell proliferation. A growth curve showing the decreased cell numbers that were counted at 3 days after transfecting either siControl (black solid line) or siCAPER (black dotted line). …”

Suppl. Fig. Kreitmeier et al., Am J Physiol Heart Circ Physiol (2021) by Klaus-Georg Kreitmeier (9985376)

“…</p><p><br></p><p> </p><p><b><u>Supplemental Figure 5:</u></b><u> Myofilament Ca²⁺ sensitivity decreases during acidosis and recovers during washout in a CaMKII-dependent manner.…”

Effect of mutants that disable CNNM Mg²⁺ efflux activity on TRPM7-mediated Zn²⁺ influx. by Zhiyong Bai (259036)

“…<i>n</i> = 50. * indicates a <i>p</i>-value of less than 0.05. <b>(C)</b> Separate control experiments were performed using the Mag-Fura-2 dye to show that the magnesium levels of 293-TRPM7 cells expressing CNNM2 are decreased compared to 293-TRPM7 cells alone and that CNNM2 mutants used in (A) do not effectively lower intracellular Mg²⁺ levels as effectively as WT CNNM2. …”

Effect of MRS on TRVPV1-mediated Ca²⁺ signaling. by Mustafa Nazıroğlu (4167676)

“…<p><b>A)</b> Schematic model of TRPV1 channel modulation by MRS in cancer cells. …”

Masked speech recognition and reading in children (Miller et al., 2018) by Gabrielle Miller (4345852)

“…Compared to adults, performance in the 2-talker masker was relatively consistent across children. Furthermore, decreasing the signal-to-noise ratio had a more precipitously deleterious effect on children’s speech recognition in the 2-talker masker than was observed for adults. …”

Pharmacokinetic and <i>ex vivo</i> pharmacodynamic properties of anti-C5 antibodies in <i>C5</i>^<i>hu/hu</i> mice. by Adrianna Latuszek (8816489)

“…In all cases, hemolytic activity decreased in a dose-dependent manner relative to the amount of serum used in the assay. …”

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near <i>CDKN2B-AS1</i>, <i>SIX6</i> and <i>GAS7</i> by Yukihiro Shiga (724428)

“…In addition, nominal correlation was observed between <i>CDKN2B-AS1</i> (rs2157719) and optic nerve head blood flow (β = -0.54 and -0.67 arbitrary units (AU), <i>P</i> = 2.00E-02 and 1.39E-02), between <i>SIX6</i> (rs33912345) and decreased total peripapillary retinal nerve fiber layer thickness (β = -2.16 and -2.82 μm, <i>P</i> = 4.68E-02 and 2.40E-02, additive and recessive model, respectively) and increased optic nerve head blood flow (β = 0.44 AU, <i>P</i> = 2.20E-02; additive model) and between <i>GAS7</i> (rs9913911) and increased cup volume (β = 0.03 mm³, <i>P</i> = 4.60E-02) and mean cup depth (β = 0.03 mm³, <i>P</i> = 4.11E-02; additive model) and decreased pattern standard deviation (β = -0.87 dB, <i>P</i> = 2.44E-02; dominant model).…”

PrP^Sc accumulation in <i>TNFR1^−/−</i> lymph nodes requires LTβR signaling independent of <i>Prnp</i> expression. by Tracy O'Connor (143972)

“…Histoblots were performed on frozen sections from spleens (SPL; A–D) or mesenteric lymph nodes (mLN; E–H) from mice in each treatment group to visualize PrP^Sc deposition. …”

Data_Sheet_2_Immunological response and temporal associations in myocarditis after COVID-19 vaccination using cardiac magnetic resonance imaging: An amplified T-cell response at th... by Hajnalka Vago (4411354)

“…</p>Methods<p>We assembled a CMR-based registry of potentially COVID-19 vaccination-related myocarditis cases. …”

Upon depletion of corneal conventional dendritic cells, virus titers and the local corneal damages are significantly increased in primary herpes simplex keratitis. by Kai Hu (311882)

“…Keratitis severity was graded (n = 5/time point). <b>A:</b> Representative corneal photos of primary acute herpes simplex keratitis severity of the mice in different groups are shown. …”

The pathway of ADF7-inhibited-VLN1 is involved in osmotic-induced F-actin depolymerization and ROS accumulation. by Shuangtian Bi (5183459)

“…Arrows represent positive regulation, and bar ends mean inhibitory action. Osmotic stress induces ADF7 expression, which leading to the inclined F-actin depolymerization and the inhibited VLN1 expression that decreases F-actin bundle. …”

<i>Dcp2</i> mutant flies fail to develop cNILH. by Jing Ren (107777)

“…<p>A. Diagram of the <i>Dcp2</i> genomic region with gene direction. …”

Table_1_Usefulness Differs Between the Visual Assessment and Specific Binding Ratio of 123I-Ioflupane SPECT in Assessing Clinical Symptoms of Drug-Naïve Parkinson’s Disease Patient... by Hidetomo Murakami (6105284)

“…SBR reflects some cognitive functions, whereas a visual assessment grade of 1, which signifies decreased uptake of ¹²³I-Ioflupane in the caudate nucleus, reflects postural instability. …”

Data_Sheet_1_Immunological response and temporal associations in myocarditis after COVID-19 vaccination using cardiac magnetic resonance imaging: An amplified T-cell response at th... by Hajnalka Vago (4411354)

“…</p>Methods<p>We assembled a CMR-based registry of potentially COVID-19 vaccination-related myocarditis cases. …”

Table_1_Immunological response and temporal associations in myocarditis after COVID-19 vaccination using cardiac magnetic resonance imaging: An amplified T-cell response at the hea... by Hajnalka Vago (4411354)

“…</p>Methods<p>We assembled a CMR-based registry of potentially COVID-19 vaccination-related myocarditis cases. …”

TRLS2^-/- mice demonstrate appropriate hormone responses to low blood glucose. by Daniel W. Fisher (4872406)

“…<p><b>A)</b> Blood glucose was assessed at two time points in <i>Trls2</i>^+/+, <i>Trls2</i>^+/-, and <i>Trls2</i>^-/- mice, one hour after lights on (top graph) and an hour after lights off (bottom graph). …”

Data_Sheet_2_Diethyl Aminoethyl Hexanoate Increase Relay Strip Intercropping Soybean Grain by Optimizing Photosynthesis Aera and Delaying Leaf Senescence.ZIP by Kai Luo (769190)

“…Merr.] yield formation in the maize-soybean relay strip intercropping (IS) and monoculture soybean (SS). A field experiment was conducted to explore the soybean yield increase mechanism of DA-6 in IS and SS treatments. …”

Negative frequency-dependence maintaining coexistence between BCs and ICs. by Albertas Janulevicius (732672)

“…<p>(A) The joint population dynamics of two genotypes (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008547#pcbi.1008547.t002" target="_blank">Table 2</a>), picked from the BC and IC subpopulations of the dimorphic population shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008547#pcbi.1008547.g005" target="_blank">Fig 5</a>, was simulated under chemostat conditions as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008547#pcbi.1008547.g005" target="_blank">Fig 5</a>, but without mutation. …”

Data Sheet 2_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…The quality assessment was independently conducted by two researchers, and any discrepancies were resolved with the assistance of a third researcher. Data were analyzed using RevMan 5.4 software, with standardized mean differences (SMD) and 95% confidence intervals (CIs) calculated. …”