Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay by Blake A Rowe (19589318)

“…</p> <p><b>Results & conclusion:</b> A larger dynamic range, high inhibition and higher drug tolerance were achieved by adding an acid dissociation step to the assay, performing atypical biotin labeling of Drug 1 and switching to a detection target that contained an Fc linker to increase steric hinderance and decrease its binding affinity to Drug 1.…”

m⁵C modified sites C131 and C2017 positively regulate HBV replication. by Jiangpeng Feng (9287738)

Alternative splicing changes involved in the muscle development in the <i>H698R</i> mutant. by Bei Zhang (428038)

The sexual stage phenotype of <i>pbpp6</i> gene knockout clones. by Yonghui Feng (12227596)

Changes in blood pressure, HbA1c, blood lipids and liver function-related indicator values from 3 months to 6 months of treatment in all patients. by Jia Song (495396)

The three schizophrenia patient clusters visualized using functional connectivity matrices. To create the visualizations, we take all the windows belonging to a cluster and average... by Eloy Geenjaar (21533195)

iNOS deficiency impairs <i>S</i>. <i>japonicum</i>-elicited Th1 and Th2 responses in rats. by Jia Shen (1828945)

PbPP6 disruption impairs the cGMP-PKG-Ca²⁺ signaling pathway. by Yonghui Feng (12227596)

Data_Sheet_1_COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging via the BDNF/ERK1/2 Signaling Pathway.docx by Yan-Bin Xiyang (9107897)

“…Moreover, mice with both COX5A overexpression and BDNF knockdown showed a poor recovery in spatial recognition memory as well as a decrease in spine density and branching of dendrites in CA1, when compared to mice that only overexpressed COX5A. …”

Data_Sheet_1.docx by Lie Zhang (5078363)

“…DUL may produce potent analgesic effects on the hyperalgesia and decrease the expressions of p-ERK through increasing the concentration of serotonin in the CeA.…”

The progression of pulmonary granuloma-associated fibrosis is slowed in iNOS-KO rats. by Jia Shen (1828945)

The <i>sf3b1-698</i> mutants are defective in fecundity and lifespan. by Bei Zhang (428038)

“…<p>(<b>A</b>) Fewer eggs were laid in the early stage by <i>sf3b1-H689D</i> and <i>-H698R</i> mutants. …”

HBV expression positively regulates expression of endogenous NSUN2. by Jiangpeng Feng (9287738)

Effect of soil source and light availability on percent mycorrhizal colonization. by Katherine E. A. Wood (17325907)

Kaplan-Meier survival plots. by Katherine E. A. Wood (17325907)

Inequalities in Alcohol-Related Mortality in 17 European Countries: A Retrospective Analysis of Mortality Registers by Johan P. Mackenbach (147412)

“…<div><p>Background</p><p>Socioeconomic inequalities in alcohol-related mortality have been documented in several European countries, but it is unknown whether the magnitude of these inequalities differs between countries and whether these inequalities increase or decrease over time.</p><p>Methods and Findings</p><p>We collected and harmonized data on mortality from four alcohol-related causes (alcoholic psychosis, dependence, and abuse; alcoholic cardiomyopathy; alcoholic liver cirrhosis; and accidental poisoning by alcohol) by age, sex, education level, and occupational class in 20 European populations from 17 different countries, both for a recent period and for previous points in time, using data from mortality registers. …”

NSUN2 depletion negatively regulates HBV expression, replication, and infection in HepG2-NTCP or primary human hepatocytes infection system. by Jiangpeng Feng (9287738)

Effect of soil source and light availability on functional traits. by Katherine E. A. Wood (17325907)

m⁵C methylation in HBV RNA contributes to HBV RNA stability. by Jiangpeng Feng (9287738)

Image_3_Cell Death Triggered by the Autophagy Inhibitory Drug 3-Methyladenine in Growing Conditions Proceeds With DNA Damage.jpeg by Javier Chicote (9521855)

“…Among them, 3-methyladenine, SBI-0206965, Chloroquine, and Bafilomycin A₁ triggered BAX- and/or BAK-dependent cytotoxicity and caspase activation. 3-methyladenine was the only compound to induce a consistent and abrupt decrease in cell viability across a series of ontologically unrelated human cell lines. 3-methyladenine-induced cytotoxicity was not driven by the inhibition of the AKT/mTOR axis. …”