The effect of leptin administration on motor function recovery in the CatWalk system. by Carmen María Fernández-Martos (5649061)

“…Leptin administration decreased the base of support (BOS) of both of the fore (A) and hind (B) paws when compared with vehicle-treated controls. …”

FHL2 silencing reduces lung metastasis in mice. by Julia Brun (286504)

“…Proposed model in which FHL2 silencing using shFHL2 in murine osteosarcoma cells attenuates Wnt/β-catenin signaling and reduces the expression of Wnt5a and Wnt10b and possibly other FHL2 target genes in the tumors, resulting in decreased osteosarcoma cell growth, invasiveness and tumorigenesis <i>in vivo</i> (D).…”

Summary of alpha connectivity changes. by Srivas Chennu (297764)

“…<p>There were significant differences in the levels of local clustering (A) and global path lengths (C) between responsive and drowsy groups during mild and moderate sedation. …”

Altered mitochondrial morphology in cumulus cells of diabetic mice. by Qiang Wang (32383)

“…<p>Cumulus-oocyte complexes collected from control and diabetic mice were subjected to transmission electron microscopy analysis and mitochondrial structure was compared. (A) Representative electron micrograph of mitochondria from control cumulus cells, showing bean-shaped structures with numerous transversely orientated cristae enveloped by an intact outer membrane; (B–C) Representative electron micrographs show alterations in mitochondrial morphology of diabetic cumulus cells: (B) small spherical mitochondria with fewer and disarrayed cristae and a decreased electron density of the matrix (arrow), and (C) mitochondria with membrane rupture or large vacuoles (arrow). …”

p53 mRNA expression and p53 protein content in mitochondria. by Zhengtang Qi (214549)

“…<p>Data are presented as mean ± SEM and displayed as arbitrary unit (A.U.) vs. β-actin (mRNA, n = 8) and COXIV (protein, n = 4). …”

Effects of methionine oxidation on the activation of FcγRIIa and FcγRIIIa by cetuximab. by Minoru Tada (321600)

“…(B) Activation of FcγRIIa and FcγRIIIa by t-BHP-treated cetuximab was measured by an FcγR reporter assay using A431 cells as target cells. Methionine oxidation caused by t-BHP treatment dose-dependently decreased the activation of FcγRIIa (*, p<0.05; ***, p<0.005), but not that of FcγRIIIa (not significant).…”

The NC algorithm reconstructs random and most small-world network topologies in all three dynamical regimes. by Sinisa Pajevic (267425)

“…NC reconstruction of the OHO network in A in the supercritical regime. Right: Corresponding analysis for and mean path length . …”

Extended Stochastic Model (Five Cells): Robustness Analysis of the Period and Amplitude of the Internal cAMP Oscillations with Respect to Perturbations in the Model Parameters and... by Jongrae Kim (36310)

“…The distributions of the amplitudes show a similar tendency, i.e., the mean decreases and the standard deviation increases as the magnitude of the perturbation increases. …”

Developmental trends of children's social play from 2 to 6 years. by Stéphanie Barbu (231438)

“…*<i>P</i><0.05, **<i>P</i><0.01, ***P<0.001 by Fisher's PLSD post hoc comparisons among age groups (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016407#pone.0016407.s001" target="_blank">Table S1</a> for complete descriptive statistics and S2 for true <i>P</i> values).…”

Western blot analysis of claudin-1 and occludin expression after apical treatment with TGFβs. by Angelika Stammler (483878)

“…<p>A: Western blot with lysates of MEPC5 after apical stimulation with TGFβ1, TGFβ2 or TGFβ3 compared to untreated cells. …”

SCI alters the mRNA expression of canonical Wnt signalling components. by Carmen María Fernández-Martos (5649061)

“…SCI did not alter the transcription of the <i>LRP5/6</i> co-receptors, although there was a striking increase in <i>GSK3-β</i> expression that coincided with that of the <i>Dkk</i> inhibitors, as well as a mild up-regulation of <i>β-catenin</i> after 6 hours that gradually decreased until the end of the study. …”

Vsp1 associates with brain endothelium. by Gaurav Gandhi (239145)

“…Notice that Eu-LVsp1 associated with HBMEC in a time-dependent manner (panels A–C); also notice that the association of LVsp1 with HBMEC was saturable (panel A), did not occur with non-lipidated rVsp1 or albumin (panel B), and decreased by incubation at lower temperature (panel C).…”

RCECs TNF-α gene expression. by Yihui Chen (446576)

“…(mean±SD, n = 3). * <i>P</i><0.05 vs. group A, # <i>P</i><0.05 vs. group B.…”

Evidence of DMXAA-mediated macrophage repolarization <i>in vivo</i>. by Charlene M. Downey (149525)

“…<p>(<b>A</b>) Spleen lysates from mice treated with 25 mg/kg DMXAA (N = 3), versus DMSO vehicle (N = 4) demonstrated decreased Arg-1, and elevated iNOS, transcripts. …”

Effect of corticosterone and/or LBP treatment on SVZ and hippocampal neurogenesis. by Benson Wui-Man Lau (205109)

“…Data are expressed as mean±SEM. Scale bars: A-C & E-G: 50 µm; I-K: 25 µm.…”

Fitness values of bacteriophage Qβ populations evolved at constant temperatures. by María Arribas (588788)

“…The fitness value obtained for the ancestor population, Qβ_0, at each temperature is indicated by a discontinuous line. Thus, bars above this line represent fitness increases relative to the ancestor and bars below the line correspond to fitness decreases. …”

Fitness values of bacteriophage Qβ populations evolved at fluctuating temperatures. by María Arribas (588788)

“…The fitness value obtained for the ancestor population Qβ₀ at each temperature is indicated by a discontinuous line. Thus, bars above this line represent fitness increases relative to the ancestor and bars below the line correspond to fitness decreases. …”

The effect of LVFX on lung damage and viral titer in influenza virus-infected mice. by Yuki Enoki (757318)

“…Treatment with LVFX at a dose of 100 mg/kg decreased the overall infiltration of inflammatory cells. …”

Shannon Diversity Scores. by Brittany E. Goldberg (765746)

“…<p>Boxplots were generated from Shannon diversity scores with quartiles represented in whisker plots and the mean identified by the central point. The Shannon score, which is a measure of species diversity within a sample, is compared between sample locations in Panel A. …”

Downregulation of tumor suppressor PTEN upon HABP1 overexpression in HepG2. by Paramita Saha (473954)

“…<p>[A-B] <b><i>Downregulation of expression of the autophagic modulator PTEN in HepR21</i></b><b>—</b> Autophagic modulator and also a known tumor suppressor PTEN was observed from immunoblots to have a significantly reduced expression (∼30%) in HepR21 cells compared to HepG2 after 60 h of growth, indicating a higher tumorigenicity of HepR21. …”