RNAi knockdown of pex3 reduces peroxisome numbers and impairs viability. by Joseph E. Faust (580247)

“…<p>(<b>A</b>) A schematic of the pex3 genomic region shows the area targeted by the inverted repeat. …”

Induction of Heme Oxygenase-1 Can Halt and Even Reverse Renal Tubule-Interstitial Fibrosis by Matheus Correa-Costa (119464)

“…Heme-oxygenase-1 (HO-1) is a cytoprotective molecule that has been shown to be beneficial in various models of renal injury. …”

Image_1_Biocontrol potential of wine yeasts against four grape phytopathogenic fungi disclosed by time-course monitoring of inhibitory activities.pdf by Marcos Esteves (14727904)

“…More notably, the approach used allowed the detection of a wide array of yeast-induced mold response profiles encompassing, besides the decrease of mold growth, the inhibition or delay of spore germination and the complete arrest of mycelial extension, and even its stimulation at different phases. …”

Data_Sheet_1_Adiponectin Mediates the Protection of H2S Against Chronic Restraint Stress-Induced Cognitive Impairment via Attenuating Hippocampal Damage.ZIP by Qiong-Yan Tang (10748115)

“…In addition, Anti-Acrp30 blocked the protective effect of NaHS on hippocampal apoptosis in rats-subjected with CRS as evidenced by the pathological changes in hippocampus tissues in hematoxylin and eosin (HE) staining and the increases in the amount of the condensed and stained to yellowish-brown or brownish yellow neuron nucleuses in terminal deoxynucleotidyl transferase transfer-mediated dUTP nick end-labeling (TUNEL) staining as well as the expression of hippocampal pro-apoptotic protein (Bax), and a decrease in the expression of hippocampal anti-apoptotic protein (Bcl-2). …”

DataSheet_1_Evaluating the Microsatellite Instability of Colorectal Cancer Based on Multimodal Deep Learning Integrating Histopathological and Molecular Data.csv by Wenjing Qiu (315272)

“…However, traditional wet-lab experiment-based MSI detection is time-consuming and relies on experimental conditions. In addition, a comprehensive study on the associations between MSI status and various molecules like mRNA and miRNA has not been performed. …”

Image_2_Automated quantification of photoreceptor outer segments in developing and degenerating retinas on microscopy images across scales.tiff by Suse Seidemann (18608065)

“…The assessments showed an increase in POS number, volume, and membrane coherency during wild-type postnatal development, while a decrease in all three observables was detected in different retinal degeneration mouse models. …”

Image_5_Automated quantification of photoreceptor outer segments in developing and degenerating retinas on microscopy images across scales.TIFF by Suse Seidemann (18608065)

“…The assessments showed an increase in POS number, volume, and membrane coherency during wild-type postnatal development, while a decrease in all three observables was detected in different retinal degeneration mouse models. …”

Data_Sheet_1_Stroke Admissions, Stroke Severity, and Treatment Rates in Urban and Rural Areas During the COVID-19 Pandemic.DOCX by Hebun Erdur (4858576)

“…<p>Background: Many regions worldwide reported a decline of stroke admissions during the early phase of the coronavirus disease 2019 (COVID-19) pandemic. …”

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production by Corin Miller (4042664)

“…The decrease in EGP was not likely due to a direct effect on the liver, as isolated perfused liver studies showed no effect of MK-2305 <i>ex vivo</i> and GPR40 is not expressed in the liver. …”

<i>In vitro</i> and <i>in vivo</i> Bioactivity of Stomoxyn. by Erick O. Awuoche (4603582)

“…</b> Gene-silencing validation: The relative expression of <i>stomoxyn</i> was measured from dsGFP and dsStomoxyn<i>-</i>treated <i>Gff</i> flies, showing a significant decrease in expression (<i>p</i><0.0001) in the case of dsStomoxyn<i>-</i>treated group. …”

Raw experimental data Fig 3. by Feline F. W. Benavides (13694053)

“…Additionally, we detected increased microglial activation in the olfactory bulb and hippocampus, and a decrease in the astrocytic activation status in the white matter and hippocampus of SARS-CoV-2 inoculated ferrets. …”

Data Sheet 1_Clinical isolates of Providencia rettgeri and Providencia Stuartii evades neutrophil-mediated killing by subverting neutrophil-extracellular traps.pdf by Joselyn E. Castro (22355326)

“…This decrease was abolished by fixed bacteria, and was dependent on the release of a DNase activity. …”

Table2_Location and Species Matters: Variable Influence of the Environment on the Gene Flow of Imperiled, Native and Invasive Cottontails.docx by Thomas J. McGreevy (11497954)

“…New England cottontail (Sylvilagus transitionalis) is the only native cottontail in the Northeast US, an early successional habitat specialist, and a species of conservation concern. Eastern cottontail (S. floridanus) is an invasive species in the Northeast US and a habitat generalist. …”

DataSheet_1_Human monocyte-derived suppressive cells (HuMoSC) for cell therapy in giant cell arteritis.docx by Maxime Samson (4439077)

“…</p>Results<p>Transcripts of genes implicated in vascular inflammation (CCL2, CCR2, CXCR3, HLADR), vascular remodeling (PDGF, PDGFR), angiogenesis (VEGF) and extracellular matrix composition (COL1A1, COL3A1 and FN1) were decreased in arteries treated with HuMoSCs or their supernatant. …”

<em>Lactobacillus rhamnosus</em> (<em>LGG</em>) Regulates IL-10 Signaling in the Developing Murine Colon through Upregulation of the IL-10R2 Receptor Subunit by Julie Mirpuri (109883)

“…Furthermore, <em>LGG</em>-dependent increases in IL-10R2 were associated with reductions in TNF-α, MIP-2 and disease severity in a murine model of intestinal injury in the immature colon.…”

Thermal Manipulation during Embryogenesis Has Long-Term Effects on Muscle and Liver Metabolism in Fast-Growing Chickens by Thomas Loyau (624425)

“…<div><p>Fast-growing chickens have a limited ability to tolerate high temperatures. …”

Image 1_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.tiff by Ru Chen (186859)

“…At the national level, countries with a high burden of OM are primarily concentrated in Sub-Saharan Africa and South Asia. …”

Table_3_Metabolomics analysis of splenectomy of Nile tilapia (Oreochromis niloticus) reveals the spleen involved in regulating liver lipids and amino acids metabolism.docx by Yixi Tao (11036286)

“…After splenectomy, biochemical parameters of the liver and serum showed abnormalities, including significant increases in total cholesterol (T-CHO) and serum total bile acid (TBA) levels, alongside a significant decrease in liver TBA levels, suggesting impaired metabolic function and cholesterol deposition in the liver. …”

Data_Sheet_2_The burden of liver cirrhosis in mortality: Results from the global burden of disease study.docx by Fei Ye (339913)

“…The ASR of mortality caused by hepatitis C virus (HCV), alcohol consumption, and non-alcoholic steatohepatitis (NASH) increased with an EAPC of 0.17 (95% CI, 0.14–0.20), 0.20 (95% CI, 0.16–0.24), 1.00 (95% CI, 0.97–1.04), respectively. A decreasing trend of ASR was found among the causes of hepatitis B virus (BV) and other causes. …”

Image_3_Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via... by Junping Bao (10931142)

“…On the contrary, further activating p-eIF2α aggravated the NP cell degeneration, with amplification of ATF4/Ihh and a higher level of ROS and apoptosis. Additionally, applying cyclopamine (CPE) to suppress Ihh was efficient to prevent NP cell apoptosis but did not decrease the ROS level. …”