Data_Sheet_1_Acute gastrointestinal injury and altered gut microbiota are related to sepsis-induced cholestasis in patients with intra-abdominal infection: a retrospective and pros... by Beiyuan Zhang (16682784)

“…Subsequently, 20 patients with IAI were recruited prospectively, with 10 patients each assigned to the non-SALD and SIC groups. Patients with SIC had a more severe gut microbiota disorder on day 7 than those without SALD, including lower microbiota diversities, decreased abundance of Firmicutes and Bacteroidetes, and increased abundance of Proteobacteria and Actinobacteria at the phylum level. …”

Table 1_Global, regional, national burden and trends of unintentional injuries from 1990 to 2021 and projections to 2035: a systematic analysis of the Global Burden of Disease stud... by Wenpeng Qin (22176736)

“…</p>Conclusion<p>Although ASIR of unintentional injuries decreased between 1990 and 2021, and the burden of such injuries is relatively lighter in regions with a high SDI, notable disparities remain across countries. …”

Table1_Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses.docx by Jing Yang (13969)

“…In particular, decreased expression levels of Mir100hg, Gm19265, Gm10544, Malat1, Zfp236, Erc2, and Hmg20a may contribute to the development of NTD.…”

Table 3_Global, regional, national burden and trends of unintentional injuries from 1990 to 2021 and projections to 2035: a systematic analysis of the Global Burden of Disease stud... by Wenpeng Qin (22176736)

“…</p>Conclusion<p>Although ASIR of unintentional injuries decreased between 1990 and 2021, and the burden of such injuries is relatively lighter in regions with a high SDI, notable disparities remain across countries. …”

Table2_Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses.docx by Jing Yang (13969)

“…In particular, decreased expression levels of Mir100hg, Gm19265, Gm10544, Malat1, Zfp236, Erc2, and Hmg20a may contribute to the development of NTD.…”

Video1_Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Ma... by Arash Pezhouman (10725644)

“…Our findings suggest that FHF-like CMs display more mature features given their enhanced sarcomeric alignment, calcium handling, and decreased migratory characteristics. Finally, pseudotime analyses revealed a closer association of the FHF population to human fetal CMs along the developmental trajectory.…”

DataSheet_1_Intra-articular delivery of AAV vectors encoding PD-L1 attenuates joint inflammation and tissue damage in a mouse model of rheumatoid arthritis.docx by Wenjun Li (41954)

“…Biodistribution of AAV vectors after intra-articular injection showed undetectable AAV genomes in other tissues except for a low level in the liver. Similar to the results of AAV5/PD-L1 vector administration on day 0, decreased joint swelling and lower histopathological damage were observed in joints treated with AAV5/PD-L1 vectors on day 21.…”

Radial distribution functions (RDFs, <i>g(r)</i>) between side-chain atoms and nonspecific ions in the solvent comparing (a) the systems at physiological and low IS, (dashed) and (... by Ayse Ozlem Aykut (493808)

“…(b) The systems at low IS with standard E31 (, same as in part a; solid line), E31A protonation (, dotted), and E31A mutation (). …”

Additional file 2 of Targeting CD276 with Adapter-CAR T-cells provides a novel therapeutic strategy in small cell lung cancer and prevents CD276-dependent fratricide by Beate Kristmann (18178291)

“…Additional file 2: Analysis of characteristics of ex vivo CAR-T (A) CD276-expression is upregulated upon stimulation of T-cells with either, IL-7/IL-15, OKT3, or TransAct. …”

Table_1_The efficacy and safety of anti-vascular endothelial growth factor combined with Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma: a systematic re... by Chang-Zhu He (19267120)

“…Compared with AGVI alone, the combination of anti-VEGF drugs and AGVI can reduce postoperative intraocular pressure (IOP) at 1 week [WMD = −4.03, 95% CI (−5.73, −2.34), p < 0.001], 1 month [WMD = −5.39, 95% CI (−7.05, −3.74), p < 0.001], 3 months [WMD = −6.59, 95% CI (−7.85, −5.32), p < 0.001], 6 months [WMD = −4.99, 95% CI (−9.56, −0.43), p = 0.032], and more than 12 months [WMD = −3.86, 95% CI (−6.82, −0.90), p = 0.011], with a higher Effective rate [RR = 1.27, 95% CI (1.18, 1.37), p < 0.001], decreased incidence of postoperative hyphema [RR = 0.24, 95% CI (0.15, 0.39), p < 0.001], reduced use of postoperative antiglaucoma medications [WMD = −0.48, 95% CI (−0.61, −0.35), p < 0.001], and decreased aqueous humor VEGF levels [SMD = −2.84, 95% CI (−4.37, −1.31), p < 0.001].…”

DataSheet_1_Dynamic Change of Thyroid Hormones With Postmenstrual Age in Very Preterm Infants Born With Gestational Age <32 Weeks: A Multicenter Prospective Cohort Study.pdf by Ranran Shi (10498970)

“…The results prompt that age-related cutoffs, instead of a single reference range, might be more useful to explain the thyroid function of VPIs. …”

DataSheet1_The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma.pdf by Jennifer Rynne (15249101)

“…The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA expression between health and asthma. …”

DataSheet1_The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma.pdf by Jennifer Rynne (15249101)

“…The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA expression between health and asthma. …”

DataSheet_1_A case report of Pseudomonas citronellolis and Escherichia coli isolated from acute suppurative appendicitis: reveals the potential intestinal colonization and pathogen... by Yugui Lin (17975168)

“…All these cases typically occurred in elderly patients with compromised or decreased immune function. Simultaneously, the epithelial barrier disruption induced by invasive biopsy procedures or gastrointestinal disorders such as gastroenteritis provided a pathway for Pseudomonas citronellolis to infiltrate the organism. …”

Tetrahydro‑4<i>H</i>‑(pyrrolo[3,4‑<i>d</i>]isoxazol-3-yl)methanamine: A Bicyclic Diamino Scaffold Stabilizing Parallel Turn Conformations by Raffaella Bucci (1528756)

“…A tetrahydro-4<i>H</i>-(pyrrolo­[3,4-<i>d</i>]­isoxazol-3-yl)­methanamine scaffold was designed as a diamino derivative to stabilize parallel turn conformations. …”

Table 3_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…</p>Conclusion<p>This study found no association between ACE2 rs2106809 genetic variant and susceptibility to SARS-CoV-2 infection, whilst the rs2285666 T-allele was associated with a decreased frequency for SARS-CoV-2 infection among Ghanaian females. …”

Table 1_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…</p>Conclusion<p>This study found no association between ACE2 rs2106809 genetic variant and susceptibility to SARS-CoV-2 infection, whilst the rs2285666 T-allele was associated with a decreased frequency for SARS-CoV-2 infection among Ghanaian females. …”

Table 2_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…</p>Conclusion<p>This study found no association between ACE2 rs2106809 genetic variant and susceptibility to SARS-CoV-2 infection, whilst the rs2285666 T-allele was associated with a decreased frequency for SARS-CoV-2 infection among Ghanaian females. …”

The cellular prion protein, PrP^C, is required for rod formation from Aβd/t and proinflammatory cytokines, but not from rods induced by glutamate or mitochondrial inhibit... by Keifer P. Walsh (504430)

“…<p>(A) Percent of neurons with rods 20 h after treatment with Aβd/t or proinflammatory cytokines measured in dissociated neurons from FVB wild type mice or from the PrP^C-null mouse made in the FVB background. …”

Image_2_Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Downregulates the Inflammatory Response in Cutaneous Leishmaniasis Patients Without Interfering in Lei... by Maurício T. Nascimento (13041501)