Human UBE3A negatively regulates the protein level of BMP receptor ALK3 in HEK293 cells. by Wenhua Li (426756)

“…(B) Increased levels of the endogenous pSmad protein and ALK3 were observed in HEK293 cells expressing reduced levels of <i>UBE3A</i> by two independent siRNAs. (C) A decreased level of the endogenous ALK3 protein was observed in UBE3A-overexpressing cells; this effect was abolished by treatment with the proteasome inhibitor MG132. …”

Overexpression of miR-132-3p inhibits the TGF-<i>β</i>1/Smad2/3 signaling pathway in TGF-<i>β</i>1 induced MET-5A cells. by Yangyang Yin (14323701)

Subjects:

The effect of MiR-132-3p on protein expression in TGF-<i>β</i>1/Smad2/3 signaling pathway was observed by immunofluorescence. by Yangyang Yin (14323701)

Subjects:

Did B inhibits early HIV-1 replication by targeting the RT-eEF1A interaction. by Dongsheng Li (222712)

“…HIV-1 containing a W252A RT mutant has decreased ability to interact with eEF1A. …”

Mean number of contacts by age group and household size. by Amy Gimma (8809463)

Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination by Taejin Kim (472963)

“…Relative to wild type RecA, the selected RecA variants exhibited faster rates of ATP hydrolysis, more rapid displacement of SSB, decreased inhibition by the RecX regulator protein, and in general displayed a greater persistence on DNA. …”

Distribution of AQI and Air pollutants indicators by provinces. by Weixin Chen (138569)

Subjects:

Kar is regulated by nutrients and FarO is a VLC fatty acyl-CoA reductase. by Einat Cinnamon (2922108)

“…<p>(A,B) Nutrients and PI3K signaling are required for maximal Kar expression. …”

Distribution of average physical fitness scores across 30 provinces. by Weixin Chen (138569)

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Protein expression profile was performed using a custom designed membrane-based protein array. by Thaiz F. Borin (4107397)

Summary of regression analyses for mean emergence times of <i>Drosophila suzukii</i> and <i>Zaprionus indianus</i> (shown in Fig 4). by Larine de Paiva Mendonça (14883146)

Effects of ATP and primer-template binding on RecA-UmuC cross-linking efficiency in pol V Mut. by Angela J. Gruber (712958)

“…<p>Western blot using an antibody to UmuC demonstrating increased UmuC-RecA cross-linking with increasing ATPγS concentration and decreasing UmuC-RecA cross-linking with increasing primer-template concentration in the presence of 500 μM ATPγS. pol V Mut was generated using RecA N113Bpa as described in Methods, with ATPγS and primer-template hairpin DNA added where indicated. …”

Selection and screening of study participants. by Weixin Chen (138569)

Subjects:

Ion Pairing and Dielectric Decrement in Glycosaminoglycan Brushes by James D. Sterling (2943375)

“…Cell–surface polysaccharides are essential to many aspects of physiology, serving as a highly conserved evolutionary feature of life and as an important part of the innate immune system in mammals. …”

CENP-A^Cse4 mislocalization to promoters alters transcription. by Erica M. Hildebrand (3178719)

“…<p>(A) Graph of the number of transcripts significantly increased or decreased compared to the WT strain by RNA-seq of <i>psh1Δ</i> and <i>htz1Δ</i> cells at t = 2 hours. …”

CRISPR/Cas9-induced <i>OsSWEET14</i> promoter modification in TBR225 rice. by Phuong Nguyen Duy (11414117)

Shadow prices of metabolites that decrease flux through reactions from Random Forest. by Deborah A. Powers (15361394)

“…<p>For each objective function (OF) listed in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011076#pcbi.1011076.g003" target="_blank">Fig 3A</a>, the metabolites categorized as decreasing and with a shadow price < -5 are shown.…”

Acetaldehyde decrease/eliminates C/EBP alpha binding to CTSL promoter sequence. by Riyaz A. Mir (350175)

An intrinsic T cell defect is responsible for the decrease in antigen-specific IFN-gamma production. by Linda A. Lieberman (152611)

Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx by Rachel A. Cederberg (12827564)

“…<p>Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues. The lungs are a common site of breast cancer metastasis and are host to a population of tissue-resident eosinophils. …”