AMPK activation reduced SREBP-2 protein and target gene expression in the livers of AICAR-treated <i>Tshr</i>^<i>-/-</i> and <i>Tshr</i>^<i>+/+</i> mice. by Shudong Liu (733425)

“…<p>(A) SREBP-2 protein levels were decreased in <i>Tshr</i>^<i>-/-</i> mice (n = 3 animals/group), Densitometric quantifications of SREBP-2 (P) and SREBP-2 (N) are shown. …”

Table_1_Altered Functional Connectivity in White and Gray Matter in Patients With Multiple Sclerosis.DOCX by Jing Huang (41604)

“…All 82 × 48 correlations for each subject formed a functional correlation matrix.</p><p>Results: Compared with the healthy controls, the MS patients had a decreased temporal correlation between the WM and the GM regions. …”

Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation by Shuai Yuan (17775132)

“…Lastly, cells lacking the CoQ synthesizing enzyme COQ6 showed decreased NOX4-derived H2O2, indicating a requirement for endogenous CoQ in NOX4 activity. …”

DataSheet1_Simultaneous silencing of juvenile hormone metabolism genes through RNAi interrupts metamorphosis in the cotton boll weevil.PDF by Daniel D. N. Vasquez (14721448)

“…Overall, the gene expression analysis showed that the treatments with PEI targeting either a single gene or multiple genes induced greater gene silencing than naked dsRNA (∼60%). …”

Table_1_Sleep Quality and Insomnia Are Associated With Quality of Life in Functional Dyspepsia.DOCX by Fabien Wuestenberghs (12058190)

“…Functional dyspepsia patients with sleep disturbances were older (48.1 ± 15.4 vs. 41.4 ± 16.0, p = 0.0009), had decreased quality of life (GIQLI: 75.3 ± 18.5 vs. 92.1 ± 15.4, p < 0.0001), greater severity of their symptoms (TSS: 18.9 ± 3.6 vs. 17.2 ± 3.9, p = 0.0007), and higher anxiety and depression scores (HADS: 17.7 ± 7.2 vs. 11.9 ± 5.1, p < 0.0001). …”

Spatiotemporal release of DZNep and gemcitabine using engineered nanoparticles reduced drug dose while potentiating chemosensitivity. by Sau Wai Hung (102677)

“…MIA PaCa-2 was treated with empty, simultaneous, or delayed NPs as above and total cell lysates were analyzed for H3K27 trimethylation using Western Blotting. A clear reduction in H3K27 trimethylation was noticed in both simultaneous and delayed NPs, with DSPE (<i>left</i>) and TPP (<i>right</i>) delayed NPs producing a slightly greater reduction compared with simultaneous NPs.…”

Stabilization of neuronal injury in SIV-infected animals following natalizumab treatment. by Jennifer H. Campbell (353635)

“…<p>(A) A decreased NAA/Cr ratio in frontal cortex (FC), (B) parietal cortex (PC), (C) basal ganglia (BG), and (D) white matter (WM), was observed in untreated and natalizumab treated animals by four weeks post infection (WPI). …”

TP53RK and BCL2L2 suppress the effects of miR-630 overexpression. by Yan Zhang (8098)

“…<p>(A) TP53RK or BCL2L2 protein caused a significantly decreased IR-induced inhibition rate in miR-630 transfected cell lines. …”

Larvicidal and macrofilaricidal efficacy of Closantel and Morantel against mosquito larvae and <i>Setaria digitata</i> nematodes by Megan Hall (506400)

“…Of all mosquito-borne diseases, dengue virus currently contributes the largest burden of cases and deaths. <i>Aedes aegypti</i> mosquitoes are a primary vector for dengue in India, and they also participate in the transmission of Chikungunya and Zika viruses (Hussain et al., 2022). …”

The results of screening the accurate strategy on the 23S-like rRNA datasets. by Yixiao Zhai (10181153)

“…<b>B</b> Sequential integration of initial alignments from MSA tools following ranking by aSP, Q, and TC scores. The ranking is derived from the "Mean" results of <b>A</b>. …”

Data_Sheet_1_Location of Parasympathetic Innervation Regions From Electrograms to Guide Atrial Fibrillation Ablation Therapy: An in silico Modeling Study.pdf by Chiara Celotto (11258451)

“…The algorithm performed better in the absence of fibrosis or when fibrosis was uniformly diffuse, with a mean accuracy of 0.94 in contrast with a mean accuracy of 0.89 for non-uniform diffuse fibrotic cases. …”

ImmTAC-mediated killing capacity is dependent on the levels of target antigen presentation. by Jane Harper (5855927)

“…NRQ = (RQ target gene/geometric mean RQ housekeeping genes) x 10⁴, RQ = Efficiency-CT. n = 3, 4, 5, 3 and 2 for Mel526, Mel624, MeWo, WM266-4 and A375, respectively. …”

Data Sheet 1_The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol.pdf by Javier Chávez Cerda (20913026)

“…A significant linear relationship was found between heart rate and respiratory rate changes, and seizure susceptibility (R² = 0.62, p-value = 0.012). …”

UA caused decline in cellular ATP and activation of AMP kinase. by Margret Bessadottir (115911)

“…<p>(A) Levels of ATP, measured in a luminometer, were decreased in T47D cells after treatment with UA (10 µg/mL; DMSO 0.2%) for 24 hours. …”

Cx43 immunostaining and quantitative analysis in the neuromuscular compartment of normal and diverticular disease human colon. by Letizia Mattii (302997)

“…<p>In normal colon, appreciable amounts of Cx43 are expressed in the circular (CM) and longitudinal muscle (LM) (A), while Cx43 expression is decreased in samples from DD colon (B); scale bar: 100 µm. …”

The microstructure of dystrophic diaphragms is dependent on region and age. by Catherine C. Henry (4416760)

“…<p>(A): As the percentage of regenerating fibers increases, sarcomere length decreases. …”

TGP treatment reduced the inhibitory neurotransmitter. by Feiye Zhu (2901245)

“…<p>The levels of NO (A), NOS (B) and VIP (C) in the MC group increased compared with that in the NC group, while they decreased after TGP treatment. …”

Etanercept ameliorates oxidative stress after myocardial ischemia/reperfusion injury. by Mei Yang (51996)

“…<p>Etanercept significantly decreased (A) the content of malondialdehyde (MDA) and (B) enhanced superoxide dismutase (SOD); and (C) glutathione peroxidase (GSH-PX) activities in ischemia reperfusion rats’ heart. …”

Characterization of septin 7 expression intensity on lymphocyte subsets by flow cytometry. by Roxane L. Degroote (532920)

“…<p>Mean intensity of septin 7 expression decreases in lymphocyte subsets of ERU cases (n = 11, dark grey curve) compared to controls (n = 11, light grey curve). …”

Effect of rapamycin on myocardial mTOR signaling in normal mice. by Kalkidan Bishu (492334)

“…Rapamycin treatment showed a strong trend towards decreasing total S6K1 expression, whereas Thr389 phosphorylated S6K1 and total and Ser235/236 phosphorylated S6 were all significantly decreased. …”