Image_1_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Image_2_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Image_5_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Image_3_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Image_4_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Image_6_Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recove... by Bernardo L. Rapoport (7431842)

“…Of the soluble co-inhibitory checkpoints, three (LAG-3, PD-L1, TIM-3) increased significantly post-NAC, reaching levels significantly greater than those of the control group. PD-1 remained unchanged, while BTLA and CTLA-4 decreased significantly (p<0.03 and p<0.00001, respectively). …”

Exogenous expression of variants of the small G protein, N-Ras, inhibits HIV-1 gene expression. by Raymond W. Wong (8463498)

“…(<b>C-D</b>) Graphs quantifying the level of expression of (<b>C</b>) HIV-1 Gag described in (<b>B</b>, n ≥ 3–5, mean, s.e.m.) and (<b>D</b>) HIV-1 RNAs detected by qRT-PCR as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008307#ppat.1008307.g002" target="_blank">Fig 2A and 2B</a> (n ≥ 3, mean, s.e.m.). …”

Data_Sheet_1_Dietary Patterns in Pregnancy and Biomarkers of Oxidative Stress in Mothers and Offspring: The NELA Birth Cohort.docx by Eva Morales (229255)

“…Maternal diet during pregnancy was assessed by a validated food frequency questionnaire and a priori-defined dietary indices (relative Mediterranean Diet [rMED], alternative Mediterranean Diet [aMED], Dietary Approach to Stop Hypertension [DASH], Alternate Healthy Index [AHEI], and AHEI-2010) were calculated. …”

Table_1_Socio-economic factors associated with mental health outcomes during the COVID-19 pandemic in South Korea.DOCX by Seo Yoon Lee (14249792)

“…Higher levels of depressive and anxiety symptoms were associated with participants who were single, reported a lower household income, had decreased support from friends or family, and increased stress from the workplace or home. …”

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx by Zhijie Zhuang (17669958)

“…Serum Klotho levels were measured using a validated ELISA assay. Sample-weighted multivariable linear regression models were used to examine the association between MDS and serum Klotho levels, adjusting for age, sex, race, socioeconomic status, lifestyle factors (smoking, alcohol use), clinical parameters (body mass index, blood pressure, lipid levels), and energy intake.…”

Data_Sheet_1_Global burden of maternal disorders attributable to malnutrition from 1990 to 2019 and predictions to 2035: worsening or improving?.docx by Tongtong Xu (4959505)

“…Both ASMR and ASDR showed a significant decreasing trend with increasing SDI. …”

Image_1_Socio-economic factors associated with mental health outcomes during the COVID-19 pandemic in South Korea.TIF by Seo Yoon Lee (14249792)

“…Higher levels of depressive and anxiety symptoms were associated with participants who were single, reported a lower household income, had decreased support from friends or family, and increased stress from the workplace or home. …”

Data_Sheet_1_Resting-State Static and Dynamic Functional Abnormalities in Active Professional Fighters With Repetitive Head Trauma and With Neuropsychological Impairments.docx by Xiaowei Zhuang (32425)

“…A linear regression model was fitted for all 168 subjects, and different t-contrast vectors were used for between-group comparisons. …”

Incompatible element-enriched mantle lithosphere beneath kimberlitic pipes in Priazovie, Ukrainian shield: volatile-enriched focused melt flow and connection to mature crust? by I.V. Ashchepkov (9289094)

“…The mantle lithosphere is sharply divided at 4.2 GPa, marked by a high temperature Cpx-Ilm-Phl trend, eclogites and changes in pyrope geochemistry. …”

Data_Sheet_1_Influence of perinatal and childhood exposure to tobacco and mercury in children’s gut microbiota.pdf by Sonia Pérez-Castro (276227)

“…</p>Discussion<p>Our findings suggest a long-term sustainable effect of prenatal tobacco exposure on the children’s gut microbiota. …”

Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at Midgestation by Ruidong Xiang (103347)

“…However, data on such effects in prenatal muscle development that could help understand unexplained variation in postnatal muscle traits are lacking. In a bovine model we studied effects of distinct maternal and paternal genomes, fetal sex, and non-genetic maternal effects on fetal myofibre characteristics and muscle mass. …”

DataSheet1_Comparative Analysis of Differentially Expressed Circular RNAs in Polarized Macrophages.docx by Rong-mei Zhou (12249074)

“…<p>Macrophage polarization is a process that macrophages exert different functions according to surrounding micro-environment. …”

Systolic blood pressure (SBP) and diastolic blood pressure (DBP) measured using an intra-aortic microtip pressure transducer catheter. by Els Moltzer (210717)

Statistical comparisons between the selected features of the VaD patients and the controls in the three frequency bands. by Delong Zhang (276735)

“…Statistical comparisons of the feature values between the VaD patients and the controls were estimated based on a two samples <i>t</i>-test. A positive (negative) <i>t</i>-value stands for a feature that was significantly increased (decreased) in the VaD group compared with the control group. …”

Chemokine levels in the BAL are reduced by rolipram and roflumilast. by Franziska M. Konrad (729813)