DN calpain-1 supports integration of vascular cord networks by enhancing the microtubule cytoskeleton. by Mien V. Hoang (239107)

“…<p>(A) MVECs transduced with DN calpain-I or calpastatin peptide (200 nM) exhibited a robust microtubule cytoskeleton relative to Empty Vector controls. …”

NF-κB regulates <i>gTlr9</i> alternative splicing. by Frank Fang-Yao Lee (2210863)

“…In contrast, inhibition of AP-1 under stimulation selectively increased the expression of <i>9B</i> only, thus decreased <i>9A</i>/<i>9B</i> ratio (gray bars in each panel) (<b>2D-F</b>). …”

Analysis of TMD-effector translocation in mutants of the T4CC. by Silke Malmsheimer (9104597)

“…</b> Relative translocation of indicated effectors in the wild type bacteria as well as in a DotM mutant (DotM1) with decreased ability to bind Glutamine-rich peptides [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012118#ppat.1012118.ref016" target="_blank">16</a>] and in strains lacking <i>icmS</i>, <i>icmW</i>, respectively. …”

The LPal inputs to RS neurons are relayed in the PT. by Gheylen Daghfous (155482)

“…Each black trace is a mean of 10 individual responses (colored traces). …”

DataSheet_1_Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing—Using Rifampicin as an Example.docx by Lina Keutzer (8895404)

“…Moreover, the imprecision (relative root mean square error) and bias in predicted doses using MIPD with IOV decreased statistically significant when a second sampling occasion was added (difference in imprecision: −9.1%, bias: −7.7%), but only marginally including a third (difference in imprecision: −0.1%, bias: −0.1%). …”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…Bland-Altman analysis revealed a mean bias of 12.98 mg·h·L^-1 between the two AUC_ss,24h estimation methods. …”

B Cell-Based Seamless Engineering of Antibody Fc Domains - Fig 7 by Koji Hashimoto (363817)

“…<p><b>Generation of Fc-mutated antibodies with enhanced affinity to Fc</b>γ<b>RIIIa</b> A) Design of donor vectors to generate hIgG1-Fc variants with mutated Fc, which were reported previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref036" target="_blank">36</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref038" target="_blank">38</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref044" target="_blank">44</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref046" target="_blank">46</a>]. …”

Effect of apicomplexan infections on the scallop condition. by Árni Kristmundsson (838846)

“…The whole and broken horizontal red lines represent the normal mean range of gonad weight observed by Thorarinsdottir [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0144685#pone.0144685.ref015" target="_blank">15</a>] from a healthy population of scallops in 1988–1990. …”

Table_1_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.docx by Thomas Kjeld (5685143)

“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”

Data_Sheet_2_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.zip by Thomas Kjeld (5685143)

“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”

Data_Sheet_1_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.zip by Thomas Kjeld (5685143)

“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”

Effects of GCGR interactor overexpression on glucagon-induced cAMP accumulation in primary mouse hepatocytes, CHO cells expressing GCGR and HepG2 stably expressing GCGR. by Junfeng Han (755026)

“…Overexpression of YWHAB in hepatocytes decreased glucagon induced cAMP accumulation (**p<0.01 when compared to hepatocytes transfected with pcDNA3.1).The results are shown as mean ± S.E. …”

Supplementary Material for: Comparison of Postoperative Neurocognitive Function in Older Adult Patients with and without Diabetes Mellitus by vanZuylen M.L. (12761705)

“…Repeated measures ANOVA showed that mean DM patient TICS-M scores decreased 30 days postoperative (<i>F</i>(2, 200) = 4.0, <i>p</i> = 0.02), with subsequent recovery 6-month postoperative, compared to stable TICS-M scores in non-DM patients. …”

Loss of dendritic arbor complexity subsequent to ischemic stroke in ipsilateral layer II/III and layer V neurons of the motor cortex. by Yuanyuan Ji (455424)

“…Note that all parameters of dendritic complexity at the ipsilateral side decreased subsequent to MCAO and that layer II/III neurons responded faster, as they already show the decreased dendritic arborization at 6 hours after MCAO (for contralateral data, see <b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001399#pbio.3001399.s003" target="_blank">S3 Fig</a></b>). …”

PKM2 is efficiently deleted in mature mSC of mutant mice. by Marie Deck (6829379)

“…<p><b>A</b>- Quantitative RT-PCR on sciatic nerve extracts shows decreased PKM1 and increased PKM2 expressions during mSC maturation. …”

Data_Sheet_2_Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study.pdf by Richard J. Nowak (304244)

“…In patients who decreased and/or stopped ≥1 IST, mean daily doses of PRED, AZA, and MMF decreased between OLE baseline and last assessment by 60.8% [standard deviation (SD), 28.07; P < 0.0001], 89.1% (SD, 25.77; P < 0.0001), and 56.0% (SD, 32.99; P < 0.0001), respectively. …”

Data_Sheet_1_Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study.pdf by Richard J. Nowak (304244)

“…In patients who decreased and/or stopped ≥1 IST, mean daily doses of PRED, AZA, and MMF decreased between OLE baseline and last assessment by 60.8% [standard deviation (SD), 28.07; P < 0.0001], 89.1% (SD, 25.77; P < 0.0001), and 56.0% (SD, 32.99; P < 0.0001), respectively. …”

Data_Sheet_1_Brief Episodes of Nocturnal Hypoxia and Acidification Reduce Survival of Economically Important Blue Crab (Callinectes sapidus) Larvae.pdf by Stephen J. Tomasetti (6061343)

“…Two experiments comparing a diel cycling DO/pH treatment (fluctuating from ∼30% air saturation to ∼103% averaging ∼66%/and from pH ∼7.26 to ∼7.80 averaging ∼7.53) to a static low DO/pH treatment (∼43%/∼7.35), a static moderate DO/pH treatment (∼68%/∼7.59), and a static control treatment (∼106%/∼7.94) indicated that survival in the diel cycling treatment was significantly lower than the moderate treatment (p < 0.05) by 75 and 48% over 96 and 48 h, respectively, despite comparable mean experimental DO/pH values. …”

Table1_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.DOC... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis revealed a similar EV size distribution in pre- and post-competition samples and a decreased concentration in post-competition samples related to pre-competition samples. …”

Table8_Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run.XLS... by M. Faraldi (13432389)

“…Nanoparticle tracking analysis revealed a similar EV size distribution in pre- and post-competition samples and a decreased concentration in post-competition samples related to pre-competition samples. …”