DataSheet_1_Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.docx by Yongsheng Ruan (4921687)

“…Moreover, SF2535 induced cell cycle arrest and decreased cell counts in B-ALL. Interestingly, SF2535 decreased the mean fluorescence intensity (MFI) of integrin α4, α5, α6, and β1 while increasing MFI of CXCR4, indicating that SF2535 may work through inside-out signaling of integrins. …”

DataSheet_1_Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.docx by Yongsheng Ruan (4921687)

“…Moreover, SF2535 induced cell cycle arrest and decreased cell counts in B-ALL. Interestingly, SF2535 decreased the mean fluorescence intensity (MFI) of integrin α4, α5, α6, and β1 while increasing MFI of CXCR4, indicating that SF2535 may work through inside-out signaling of integrins. …”

Data_Sheet_1_Not All Liver Abscesses Are Created Equal: The Impact of Tylosin and Antibiotic Alternatives on Bovine Liver Abscess Microbial Communities and a First Look at Bacteroi... by Lee J. Pinnell (5633090)

“…<p>Liver abscesses (LAs) are extremely prevalent in cattle and result in significant economic losses due to liver condemnation, decreased growth and production, and lower carcass quality. …”

Table 1_Comparison of preoperative education by artificial intelligence versus traditional physicians in perioperative management of urolithiasis surgery: a prospective single-blin... by Hui Zhang (7197)

“…The AI groups then had a 30 min Q&A with their assigned AI, and the physician group received an additional face-to-face session. …”

Gamma effect and EC₅₀ values for (a, b) control; (c, d) strategy I; (e, f) strategy II; (g, h) strategy III; (i, j) strategy IV. by Saurabh Sudha Dhiman (603779)

Data_Sheet_1_Gender-Specific Inverse Associations Between Beans Intake, Serum Urate Levels, and Hyperuricemia: A Cross-Sectional Analysis Based on the Henan Rural Cohort Study.docx by Ningning Cui (9533013)

“…Per 10-g increment in beans intake created a 1% decreased risk of hyperuricemia in men and 3% in women. …”

Prevalence, Risk Factors, and Antibiotic Intervention of Lower Airway <i>Pseudomonas aeruginosa</i> Colonization in Patients with Stable Chronic Obstructive Pulmonary Disease: a Sy... by Yanbing Liu (1450501)

“…Previous exposure to antibiotics and ICSs was associated with increased PA colonization, with odds ratio (OR) values of (OR = 2.85, 95% CI 1.62–5.01) and (OR = 1.89, 95% CI 1.12–3.19), respectively. Exacerbations decreased within the next year after azithromycin treatment (standardized mean difference [SMD] = −0.43, 95% CI −0.77 to −0.10). …”

Table_2_Low Incidence and Mortality by SARS-CoV-2 Infection Among Healthcare Workers in a Health National Center in Mexico: Successful Establishment of an Occupational Medicine Pro... by Miguel Ángel Salazar (10588691)

“…</p><p>Conclusion: INER has a lower incidence of HCWs infected with SARS-CoV-2 as compared to the mean of the national report. …”

Table_1_Low Incidence and Mortality by SARS-CoV-2 Infection Among Healthcare Workers in a Health National Center in Mexico: Successful Establishment of an Occupational Medicine Pro... by Miguel Ángel Salazar (10588691)

“…</p><p>Conclusion: INER has a lower incidence of HCWs infected with SARS-CoV-2 as compared to the mean of the national report. …”

Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste... by Yunfeng Yao (7136525)

“…It was found that both PTGM and PT remarkably decreased the average bulk density (BD), while elevated the mean soil porosity (SP) in 0–30 cm soil layer. …”

Data_Sheet_1_Microbial communities in the liver and brain are informative for postmortem submersion interval estimation in the late phase of decomposition: A study in mouse cadaver... by Linlin Wang (289071)

“…Eighteen taxa in the liver which were mainly related to Clostridium_sensu_stricto and Aeromonas, and 26 taxa in the brain which were mainly belonged to Clostridium_sensu_stricto, Acetobacteroides, and Limnochorda, were selected as potential biomarkers for PMSI estimation based on a random forest algorithm. The PMSI estimation models established yielded accurate prediction results with mean absolute errors ± the standard error of 1.282 ± 0.189 d for the liver and 0.989 ± 0.237 d for the brain.…”

datasheet1_Exploring the Influences of Temperature on “H-Shaped” Glycerol Dialkyl Glycerol Tetraethers in a Stratigraphic Context: Evidence From Two Peat Cores Across the Late Quat... by Xiaotong Tang (10058231)

“…<p>Unusual “H-Shaped” branched and isoprenoidal glycerol monoalkyl glycerol tetraethers (GMGTs, or H-GDGTs) have been found in peat, lake, and ocean sediments. A survey of recent samples from a modern global peat database suggested that there is a relationship between the abundance of H-GDGTs relative to regular GDGTs and temperature. …”

DataSheet_1_Trends in radiotherapy administration in the management of hepatocellular carcinoma: Analysis of a Korean tertiary hospital registry of hepatocellular carcinoma patient... by Bong Kyung Bae (8736945)

“…With the technical developments, the overall survival (OS) of patients who received radiotherapy as initial management increased significantly (5-year OS: from 5.4% to 30.1%), and the OS difference between patients who did and did not receive radiotherapy as initial management significantly decreased (ratio of restricted mean survival time: from 0.383 to 0.544).…”

Data_Sheet_1_Evaluation of the E-Mental Health Mindfulness-Based and Skills-Based “CoPE It” Intervention to Reduce Psychological Distress in Times of COVID-19: Results of a Bicentr... by Alexander Bäuerle (9207092)

“…Secondary outcomes: There was a significant decrease in depressive symptoms and generalized anxiety, and a significant increase in self-efficacy and mindfulness between baseline (T0) and post-intervention (T1). …”

Data_Sheet_1_Genetic Structure of a Worldwide Germplasm Collection of Prunus armeniaca L. Reveals Three Major Diffusion Routes for Varieties Coming From the Species’ Center of Orig... by Hedia Bourguiba (8887241)

“…Altogether, our results revealed that apricot spread from China and Central Asia, defined as the center of origin, following three major diffusion routes with a decreasing gradient of genetic variation in each geographical group. …”

Data_Sheet_1_The effect of conjugated linoleic acid supplementation in comparison with omega-6 and omega-9 on lipid profile: a graded, dose–response systematic review and meta-anal... by Camellia Akhgarjand (13115187)

“…With regard to TC level, CLA supplementation compared with placebo significantly reduced TC concentrations (WMD: −0.08 mmol/L; 95% CI: −0.14 to −0.02; p < 0.001; I² = 82.4%). Moreover, the non-linear dose–response analysis indicated a decreasing trend of TC serum level from the 15th week of CLA supplementation compared with olive oil (P_{non-linearity} = 0.01). …”

Productivity, efficiency, and overall performance comparisons between attendings working solo versus attendings working with residents staffing models in an emergency department: A... by Richard D. Robinson (1452979)

“…When paired with Residents, the API decreased for those Attendings who had a higher API when working solo (average API dropped from 0.21 to 0.19), whereas API increased for those who had a lower API when working solo (average API increased from 0.13 to 0.16).…”

Nox1*^/Y mice have a greater percentage of CD127⁺ NP-specific CD8⁺ T cells at day 15. by Amelia R. Hofstetter (2512756)

“…CD127 and KLRG-1 staining was analyzed on D^b-NP-IAV pentamer⁺ cells among CD8⁺ cells as demonstrated in the representative FACS dot plots taken from day 15 p.i. samples in A and B. Results in C-F plotted as individual mice with horizontal bar indicating mean. 2-way ANOVA indicates that the Nox1*^/Y genotype contributes to increased lung CD127⁺ cells (C, <i>p</i> < 0.001) and decreased double-negative CD127^-KLRG-1^- expressing cells (E, <i>p</i> < 0.0001; F, <i>p</i> < 0.05). …”

Glycoprotein YKL-40: A potential biomarker of disease activity in rheumatoid arthritis during intensive treatment with csDMARDs and infliximab. Evidence from the randomised control... by Tuija Väänänen (4392307)

“…<div><p>Objective</p><p>YKL-40, a chitinase-like glycoprotein associated with inflammation and tissue remodeling, is produced by joint tissues and recognized as a candidate auto-antigen in rheumatoid arthritis (RA). …”

Data_Sheet_1_Improvements in High-Density Lipoprotein Quantity and Quality Contribute to the Cardiovascular Benefits by Anti-tumor Necrosis Factor Therapies in Rheumatoid Arthritis... by Yonghong Luo (6111161)

“…Anti-TNF therapies were associated with significant increase in TC [mean difference (MD): +0.14, +0.23, and +0.26 mmol/l, respectively] and HDL (MD): +0.11, +0.12, and +0.11 mmol/l, respectively) in the short-, mid-, and long-term; anti-TNF therapies were associated with increased low-density lipoprotein (LDL) (MD: +0.06 mmol/l) and apolipoprotein A1 (ApoA1) (MD: +0.07 g/l) in the short-term, but not in the mid-term and long-term; triglyceride (TG) and apolipoprotein B (ApoB) do not change significantly in all the periods; proatherosclerotic indexes (TC/HDL, ApoB/ApoA1, and LDL/HDL) tend to decrease in the short- and mid-term, but return to baseline in the long-term after TNF inhibition.…”