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mean decrease » a decrease (Expand Search)
greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
mean decrease » a decrease (Expand Search)
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47021
GBE modulated the activities of mitochondrial ETS enzymes.
Published 2010“…(<b>A–C</b>) Values represent the means ± S.E., GBE treatment effect, paired student's t-test, number of pairs n = 4–6: #, p<0.05, ##, p<0.01 GBE treated versus corresponding untreated cells; and effect of Aβ, unpaired student's t-test, n = 4–6, **, p<0.01; ***, p<0.001 APP versus control cells.…”
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47022
Effect of METH administration on Otx2, Wnt1, Shh and Fgf8 mRNA expression in the midbrain.
Published 2011“…<p>There were increases in Otx2 mRNA expression only in the METH-preteated group challenged twice with toxic doses of the drug (A). Animals challenged twice with METH showed significant decreases in Wnt1 expression (B). …”
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47023
Levodopa treatment induced apoptotic cell death in NPCs.
Published 2012“…<p>Levodopa treatment significantly increased caspase-3 activity in a time-dependent manner in NPCs. Moreover, caspase-3 activity was significantly higher in the levodopa-treated NPCs than in the control or PPX-treated NPCs at 72 h (A). …”
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47024
Effect of dyes on the relative expression levels of the three DyP genes.
Published 2019“…<p>The expression patterns of the genes <i>Pleos-dyp1</i>, <i>Pleos-dyp2</i> and <i>Pleos-dyp4</i> in response to the addition of synthetic dyes during the time-course of a submerged <i>Pleurotus ostreatus</i> fermentation with <b>(A)</b> AYG, <b>(B)</b> RBBR and <b>(C)</b> AB129. …”
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47025
Mycolactone induces IL-1β secretion by activating the NLRP3/1 inflammasome pathway.
Published 2020“…</b> The addition of MCC950, a specific inhibitor of the NLRP3 inflammasome, at a concentration of 0.1 μM or 1 μM, significantly decreased IL-1β secretion in the presence of either mycolactone or CPPD. …”
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47026
Effects of TCS on HeLa cell cycle progress and cell cycle regulatory proteins.
Published 2013“…Cell number of S phase increased significantly (A) and expressions of cyclin A, D1 and CDK2, 4 significantly decreased (B). …”
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47027
Immunohistochemical (IHC) analysis of the aortae of TIC-, CLO-, and CTL-treated animals.
Published 2019“…<p>Abbreviations: CTL, control; CLO, clopidogrel; TIC, ticagrelor; A.U., arbitrary units; F4/80, F4/80 antigen also known as adhesion G protein-coupled receptor E1 (EMR1); MΦ, macrophages; α-SMA, alpha smooth muscle cell actin; VSMC, vascular smooth muscle cells; S100A4, S100 calcium-binding protein A4; FB, fibroblasts; TGFβ1, transforming growth factor β1; 4-HNE, 4-hydroxynonenal; P-IRE1, phosphorylated inositol-requiring enzyme 1; Size bars, 300 μm; N = 13–18, 6–7, 13–18, 6–7, 11–17, and 6–7 per group for (A), (B), (C), (D), (E), and (F), respectively; Error bars, means ± SD, statistical analyses performed using ANOVA with Fisher’s multiple comparison; NS, not statistically significant; *, P < 0.05; **, P < 0.01. …”
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47028
Dynamics of chromatin accessibility and gene expression are correlated during metamorphosis.
Published 2019“…(B) Dynamic open chromatin peaks were organized into 18 k-means clusters, displayed as a heatmap representing the fraction of the maximum FAIRE rpkm value. …”
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47029
Soil analyses along the stress gradient.
Published 2017“…<p>Soil analyses (means ±SE) of the mesocosms having different intensities of stress (low stress: SL, medium stress: SM, and high stress: SH) in 2009 (a) and 2014 (b). …”
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47030
Kinetics of Ldt<sub>fm</sub> inactivation by imipenem, ceftriaxone, and ampicillin.
Published 2013“…Regression analysis was performed with equation F<sub>t</sub> = F<sub>eq</sub>+ΔF e<sup>−<i>k</i>obst</sup> in which F<sub>eq</sub> and F<sub>t</sub> are the fluorescence intensities at equilibrium and at time t, respectively, ΔF is the difference between fluorescence intensity at time = 0 and at equilibrium, t is time, and <i>k</i><sub>obs</sub> is a constant. The resulting rate constants (<i>k</i><sub>obs</sub>) increased linearly with the drug concentration (E) and the slope provided an estimate of the efficiency of enzyme acylation (F).…”
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47031
Disappearing Scales in Carps: Re-Visiting Kirpichnikov's Model on the Genetics of Scale Pattern Formation
Published 2013“…We observed phenotypic changes which were not restricted to nudes, as described by Kirpichnikov, but were also present in mirrors (and presumably in linears as well; not analyzed in detail here). We propose that the gradation of phenotypes observed within the scattered group is caused by a gradually decreasing level of signaling (a dose-dependent effect) probably due to a concerted action of multiple pathways involved in scale formation.…”
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47032
BALB/C nude mouse subcutaneous transplantation tumor experiment and immunohistochemistry of the transplanted tumors.
Published 2018“…<i>OVOS2</i> downregulation significantly decreased tumor growth and one tumor spontaneously regressed in the A375/<i>OVOS2</i>-shRNA group. …”
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47033
Effect of surfactant and electron treatment on the electrical and thermal conductivity as well as thermal and mechanical properties of ehylene vinyl acetate/expanded graphite compo...
Published 2015“…The thermal conductivity linearly increased with EG content, and this increase was more pronounced in the case of SDS-EG, but decreased after EB irradiation. …”
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47034
Data_Sheet_1_Europium-Doped Ceria Nanowires as Anode for Solid Oxide Fuel Cells.pdf
Published 2020“…The results demonstrate: (1) Oxygen vacancies can be energetically favorably introduced into the CeO<sub>2</sub> lattice by Eu doping; (2) The lattice parameter of the ceria increases linearly with the Eu content when it varies from 0 to 35 mol.%, simultaneously resulting in a significant increase in oxygen vacancies. …”
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47035
Dry matter intake and ruminal fermentation parameters in goats fed sugarcane in replacement of corn silage
Published 2022“…However, the acetate:propionate ratio linearly decreased with increased sugarcane content. …”
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47036
The average time cost and accuracy of the assessed secondary structure prediction methods as the sequence homology of the target dataset reduces.
Published 2020“…The lowest sequence identity was 25% because when a lower identity such as 20% was applied, the number of sequences remaining in the target dataset would be far smaller than the 5 million safety zone (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.g002" target="_blank">Fig 2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.s016" target="_blank">S6 Table</a>) and then cause unreasonable decreases of the accuracy. …”
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47037
SMAD2/3 and TGF-ß1 suppress expression from the megalin promoter.
Published 2019“…Cells expressing the megalin promoter construct showed a 50% decreased in luciferase activity when the SMAD transcription factors were overexpressed. …”
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47038
Interleukin- 6 and micoRNA –mir 21- related network.
Published 2008“…Red (and pink) means significantly increased gene expression and blue decreased. …”
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47039
Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose
Published 2014“…We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. …”
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47040
Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose
Published 2014“…We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. …”