Influence of electrospinning parameters on morphology and size of silk fibroin fibers by Ana Gaviria (3470999)

“…<p></p><p>ABSTRACT The processing of silk fibroin (SF) by means of the electrospinning technique has opened a wide field of possibilities to generate fibrillar membranes at micro and nanometric scale, which together with the biocompatibility properties and outstanding mechanical properties of this protein, enhance its use in various engineering and biomedical applications. …”

Delivery of the lysosomal enzyme β- galactosidase is impaired in p110α knockdown cells. by Emily P. Thi (176454)

“…<p><b>A)</b> Knockdown of p110α results in decreased acquisition of the lysosomal enzyme β- galactosidase by phagosomes containing either BSA coated beads or M. smegmatis. …”

The effects of Dysbindin on MARCKS expression levels. by Hiroaki Okuda (254546)

“…At P45, Wild-type mice showed significant decreased MARCKS expression, while Dysbindin KO mice showed a maintained MARCKS expression. …”

BEEM-Static robustly filters samples violating modeling assumption in simulated and real datasets. by Chenhao Li (822769)

“…<p>(A-B) Performance reduction for BEEM-Static (with filters) and the naïve algorithm (without filtering of samples) as the percentage of samples at (A) equilibrium or (B) generated from the main model, decreases. …”

Expression and inhibition of hsa-miR-17-5p in Huh7.5.1 cells. by Akihito Tsubota (562807)

“…<p>(<b>A</b>) Functional suppression (left) and overexpression (right) plasmids of miR-17-5p. …”

TORC1 has little impact on the interaction between Pah1 and the Nem1-Spo7 module. by Emmanuelle Dubots (613904)

“…Please note that loss of Spo7 consistently resulted in decreased levels of Nem1. For details see (A). WT and Δ denote wild-type and deleted version(s), respectively, of the indicated gene(s). …”

Control of nongenetic heterogeneity in growth rate and stress tolerance of <i>Saccharomyces cerevisiae</i> by cyclic AMP-regulated transcription factors by Shuang Li (146392)

“…Our results shed light on the genetic control of nongenetic heterogeneity and suggest a possible means of defeating bet-hedging pathogens or tumor cells by making them more uniformly susceptible to treatment.…”

The Type III Effectors NleE and NleB from Enteropathogenic <em>E. coli</em> and OspZ from <em>Shigella</em> Block Nuclear Translocation of NF-κB p65 by Hayley J. Newton (103058)

“…<div><p>Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. …”

Bifurcation Diagram Showing the Parameter Regions where Evolutionary and Cryptic Cycles Result from Rapid Prey Evolution in Model (1) by Takehito Yoshida (273131)

“…<p>This diagram is drawn for the Abrams-Matsuda [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050235#pbio-0050235-b038" target="_blank">38</a>] model (Equation S1.1 in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050235#pbio-0050235-sd001" target="_blank">Protocol S1</a>) in which <i>r</i> plays the role of the birthrate parameter θ. …”

Transcriptomic analysis of the long-lived and short-lived Atg1 over-expressing flies reveals altered immunity and mitochondrial function. by Ivana Bjedov (75652)

“…Data are means ±SEM of n = 3 replicates. Statistical significance was calculated by a one-way ANOVA Tukey-Kramer (HSD) test (*, p<0.05; **, p<0.01; *** p<0.001). …”

Full-length AKAP13 mRNA levels are reduced by the gene-trap events. by Matthew J. Spindler (407529)

“…All three gene-traps decreased expression of the E37-38 exon-exon junction in a dose-dependent manner. …”

ML141 or wiskostatin treatments stimulate CFTR endocytosis. by Romain Ferru-Clément (701878)

“…<p>(A) Representative Western blots and (B and C) histograms summarizing the data are presented. …”

Cell proliferation of BmN4-SID1 cells expressing insect ANTs under knockdown of the endogenous BmANTI1. by Ryohei Sugahara (699858)

“…Error bars represent the SD values of the means of triplicate wells. Differences in cell proliferation rate between BmANTI1-knockdown cells and cells soaked in VENUS dsRNA were evaluated with a two-tailed Student’s <i>t</i>-test. …”

Effects of Circularity Interventions in the European Plastic Packaging Sector by Ciprian Cimpan (16469128)

“…By means of a mixed-unit input–output (IO) model, we performed a comparative scenario analysis for the development of demand and waste management up to 2030 within the EU-28 (EU27 + United Kingdom). …”

Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin by Nivin N. Nyström (13118188)

“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd­(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd­(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn­(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn­(III)­TriCP-PhOEt), which exhibited significantly higher <i>r</i>₁ relaxivity than Gd­(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”

Variability of Coastal and Ocean Water Temperature in the Upper 700 m along the Western Iberian Peninsula from 1975 to 2006 by Fran Santos (113729)

“…The analysis was carried out by means of the Simple Ocean Data Assimilation (SODA). …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Comparison of SPTAN1 in MLH1-proficient vs. MLH1-deficient CRCs. by Anne Ackermann (6443975)

“…SPTAN1 was significantly increased in MLH1-proficient tumors compared with the normal mucosa, while MLH1-deficient tumors showed a clear trend of decreased SPTAN1 levels compared with surrounding normal tissue. …”

Enforced expression of Mfn2 and DRP1 relieves Vpr-induced apoptosis. by Chih-Yang Huang (54970)

“…<b>D,</b> Overexpression of Mfn2, DRP1, and Mfn2/DRP1 reduced Vpr-induced apoptosis. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033657#s2" target="_blank">Results</a> are the means ± S.D. of three independent experiments. …”

<b>Pirani Gauge: Function, Calibration, and Use in Pharmaceutical Freeze-Drying</b> by Geoff Smith (6064268)

“…During freeze-drying, this results in <b>higher readings while ice is sublimating</b>, and the signal decreases as sublimation slows. Importantly, the <b>end of ice sublimation can occur during (but often around the midpoint) of the step-down in the Pirani signal</b>, meaning the gauge alone cannot precisely identify the sublimation endpoint. …”