Trends over 10 years (2011–2021) in clinical characteristics of children with severe acute malnutrition admitted at Moyo NRU. by Mphatso Nancy Chisala (20477275)

Trends over 10 years in children with severe acute malnutrition admitted at Moyo NRU. by Mphatso Nancy Chisala (20477275)

Figure showing the changes in the mean Raman intensity of diabetic SD rat’s blood at bands centered at wavenumbers 1125, 1395 and 1437 cm⁻¹ assigned to glucose, leucine... by Zephania Birech (4446376)

Combination treatment of NPRL2 and cisplatin induces strong cell arrest in G2/M phase. by Gitanjali Jayachandran (2774)

“…Bars, SDs of the mean from three individual experiments.</p>…”

Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status by Cæcilie Trier (700327)

“…Both the mothers and fathers lost weight during their child’s treatment with a mean decrease in BMI in the mothers of 0.5 (95% CI: 0.2–0.8, <i>p</i> = 0.0006) and in the fathers of 0.4 (95% CI: 0.2–0.6, <i>p</i> = 0.0007). …”

Dynamics of Premixed Hydrogen-Air Flames in Microchannels with a Wall Temperature Gradient by Aswathy Nair (753246)

“…Detailed studies on the formation of flames with repetitive extinction and ignition (FREI) mode have been carried out for a 0.75-mm diameter tube with fixed conditions of flow velocity of 10 cm/s and Φ = 0.5–1.0 with wall temperature linearly varying from 300 K to 960 K. …”

Network fusion. by Justine Y. Hansen (17041502)

“…(c) Edge weight decreases exponentially with Euclidean distance. (d) Structurally connected edges have greater edge weight than edges without an underlying structural connection, against a degree and edge-length preserving null model [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002314#pbio.3002314.ref056" target="_blank">56</a>] (left), and is correlated with structural connectivity (right). …”

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

“…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”

Lymphatic density (LD; a) and blood vessel density (BD; b) in the myocardium by Y Ishikawa (46340)

eQTLs with a nominally significant GWAS p value in the replication data. by Frank P. Diekstra (172218)

“…For the eQTL direction of effect, ‘+’ means the SNP minor allele was associated with increased expression levels, ‘–’ means decreased gene expression. …”

Neuronal overexpression of antioxidants reduces sleep, suggesting a role for ROS in sleep regulation. by Vanessa M. Hill (5508401)

“…Each data point represents average sleep in minutes/day measured across 5 days in an individual animal; data are shown as mean ± SEM. <i>p</i>-values were obtained by ordinary one-way ANOVA followed by a post hoc Tukey test when significance was detected. …”

Pharmacological characterization of the UT-mediated inhibition of the GABA_AR currents. by Laurence Desrues (167370)

“…Bottom row, plot of the positive correlation (r² = 0.8) of <i>h</i>UII-induced inhibition as function of the DMCM-evoked current decrease (<i>n</i> = 28). (C) Comparison of the inhibitory effect of <i>h</i>UII and URP on CHO-UT-GABA_AR as summarized in bar graphs (<i>n</i> = 12–54). …”

Exogenous <i>miR-146a</i> expression enhances OSCC oncogenicity. by Pei-Shi Hung (489732)

“…Lower, TNFα treatment up-regulates <i>miR-146a</i> expression in OSCC cells. (B) The OSCC cell subclones show an increase in <i>miR-146a</i> expression (Upper), an increase in <i>miR-146a</i> activity and a decrease in NFκB activity (Lower). …”

A Randomized, Crossover Study to Evaluate the Pharmacokinetics of Amantadine and Oseltamivir Administered Alone and in Combination by Dennis Morrison (272746)

“…Among the therapies considered for use in pandemic influenza is the co-administration of ion channel and neuraminidase inhibitors, both to potentially increase efficacy as well as to decrease the emergence of resistant isolates. To better understand the potential for drug interactions, a cross-over, randomized, open-label trial was conducted with amantadine, 100 mg po bid, and oseltamivir, 75 mg po bid, given alone or in combination for 5 days. …”

DNA2 and RPA1 promote resection resulting in a-HDR or mutagenesis at nicks. by Yinbo Zhang (591203)

“…Frequency values represent the mean ± SEM from a representative experiment; *** indicates p<0.001 for the frequency difference between the indicated sample and sample expressing RPA1-WT. …”

The relative mutation probabilities as a function of mutation site conservation and solvent accessibility by Dennis Vitkup (2575)

“…Because the overall probability that a random mutation will cause a genetic disease or be observed as a polymorphism is not known, the probabilities have only relative meaning within each mutation class (disease, synonymous, nonsynonymous). …”

Image 2_Huashi Runzao decoction for primary Sjögren disease: a double-blind, randomized controlled trial combined with m6A and m5C RNA modification analysis.tif by Ziwei Huang (192096)

“…Moreover, HRD increased m6A levels and decreased m5C levels in pSD patients, and HNRNPA2B1 was identified as a potential key epigenetic regulator.…”

Image 1_Huashi Runzao decoction for primary Sjögren disease: a double-blind, randomized controlled trial combined with m6A and m5C RNA modification analysis.tif by Ziwei Huang (192096)

“…Moreover, HRD increased m6A levels and decreased m5C levels in pSD patients, and HNRNPA2B1 was identified as a potential key epigenetic regulator.…”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Data for transition rates and costs of Phase I, II, and III trials are based on published cost estimates <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-DiMasi2" target="_blank">[3]</a> and reported clinical phase transition probabilities for investigational oncology compounds from the 20 largest firms (by pharmaceutical sales in 2005) from 1993 to 2002 <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-DiMasi1" target="_blank">[2]</a>,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Roberts1" target="_blank">[4]</a>. …”

WTA stimulates in vitro T-cell activation by a MHC-II dependent mechanism. by Christopher Weidenmaier (240364)

“…SEA was considerably more active than WTA (panel D). Values represent means ± SEM, n = 6. B) T-cell proliferation assays with WTA from wt and <i>dltA</i> were performed in the presence of blocking Abs to the MHC class II molecules and the appropriate isotype control. …”