The mature form of miR-33a, miR-33a-5p downregulates the β-catenin gene. by Yi Fang (287944)

“…The β-catenin protein levels were normalized relative to β-actin in (A). (C) miR-33a-5p decreases β-catenin mRNA levels in Chang liver and HepG2 cells. …”

Increased total cell counts and pro-inflammatory cytokines in BAL fluid from SP-A -/- mice. by Anastasia K. Ketko (491544)

“…Data are mean ± SEM with n = 8 mice per group combined from 2 or more experiments, *p<0.05 compared to SP-A+/+ mice.…”

Cilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal Cells - Fig 4 by So Youn Park (141327)

“…<p><b>A</b>. Significant enhancement of LC3-II levels by cilostazol (10 or 30 μM). …”

Mucosal turnover in the duodenum and the jejunum following different diets at T1 and T2 post-weaning periods. by Marcella Massimini (5678543)

Effects of A1AR expression on response to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…Mean ± SEM are shown. * p<0.01, ** p<0.0001, A1AR−/− compared to A1AR+/− at each me point.…”

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation - Fig 1 by Femke van Diggelen (6499112)

Adaptation following drug washout. by Alma Beatrix Stier (20903134)

Recombinant IL-4 suppressed the stimulatory effect of PGI₂ analogs on IL-17A expression. by Weisong Zhou (165396)

“…<p>CD11c⁺ cell-containing CD4⁺CD62L⁺ cells isolated from spleens of OT II mice were activated with OVA_323–339 (1 µg/ml) and anti-CD28 (1 µg/ml) in the presence of IL-23 (10 ng/ml) and treated with iloprost, cicaprost, or respective vehicles for 4 days. (A and B) Iloprost and cicaprost decreased IL-4 production, but not IFN-γ production as determined by ELISA. …”

Mean star-like bundles' length, <i>L_Fin</i>, dependence on the [Arp2/3] and [fascin]. by Yaron Ideses (270357)

“…<p>(a) Conditions are: [G-actin] = 7 µM; [Arp2/3] = 6.25 nM (green dots), 25 nM (blue dots), and 100 nM (red dots). …”

Efficient assembly of CENP-A at centromeres requires SMC2. by Alexander Samoshkin (260480)

“…<p>A) CENP-A levels are not significantly decreased in condensin-depleted cells. …”

Vitamin A supplementation reduces the Th17-Treg – Related cytokines in obese and non-obese women by Mahdieh Abbasalizad Farhangi (7513307)

“…However, the initial concentrations of other cytokines were not significantly different between groups. The mean concentrations of IL-17 and TGF-β were significantly decreased after vitamin A supplementation in non-obese and obese women respectively. …”

<i>In vivo</i> dynamic near-infrared fluorescent imaging of A-431 tumor models. by Lingbo Zhang (132359)

“…<p>A: The representative fluorescence images of the tumor regions in mice were acquired at 4 h post injection of EGF-Cy5.5. …”

The IL-17A response of CD4⁺ PBMCs to HP-pulsed APCs. by Victoria Serelli-Lee (156487)

“…<p>The mean ± SEM (standard error of mean) has been depicted for measurements of IL-17A concentration in the supernatant of co-culture experiments performed as described in the legend for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039199#pone-0039199-g003" target="_blank">figure 3B</a>. …”

Effects of Chloroquine, A. fumigatus infection, and AdipoRon treatment on LC3 expression in WT and <i>Adipoq-/-</i> AMs by Sri Harshini Goli (20889928)

Image4_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image1_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image3_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image2_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Unclustered ephrin-A5-Fc and EphA4-Fc partially reduce astrocytic gliosis. by Yona Goldshmit (205708)

“…<p>(A–C) Immunohistochemical analysis of GFAP expression 4 days after spinal cord hemisection and following 3 days administration of Fc fusion protein indicated that, (A) compared to PBS treatment (<i>n</i> = 6), ephrin-A5-Fc (<i>n</i> = 3) and EphA4-Fc (<i>n</i> = 3) treatment decreased astrocytic gliosis. …”

Attenuation of bleomycin-induced lung fibrosis upon anti-IL-17A treatment. by Paméla Gasse (209357)

“…Active MMP-2 upregulated upon BLM in the BALF of wild-type mice was greatly reduced after 6 treatments with neutralizing antibody against IL-17A (A). TIMP-1 in lung was also significantly decreased after treatment with neutralizing antibody against IL-17A in comparison to untreated BLM mice (B). …”