Image3_Volume overload impedes the maturation of sarcomeres and T-tubules in the right atria: a potential cause of atrial arrhythmia following delayed atrial septal defect closure.... by Zhuoya Dong (5048324)

“…Accordingly, the calcium handling capacity of cardiomyocytes from postnatal day 21 (P21) RA was decreased by VO. VO caused a significant elongation of the PR interval. …”

Table1_Volume overload impedes the maturation of sarcomeres and T-tubules in the right atria: a potential cause of atrial arrhythmia following delayed atrial septal defect closure.... by Zhuoya Dong (5048324)

“…Accordingly, the calcium handling capacity of cardiomyocytes from postnatal day 21 (P21) RA was decreased by VO. VO caused a significant elongation of the PR interval. …”

Image4_Volume overload impedes the maturation of sarcomeres and T-tubules in the right atria: a potential cause of atrial arrhythmia following delayed atrial septal defect closure.... by Zhuoya Dong (5048324)

“…Accordingly, the calcium handling capacity of cardiomyocytes from postnatal day 21 (P21) RA was decreased by VO. VO caused a significant elongation of the PR interval. …”

<i>GATA6</i> expression signature. by Kevin A. Kwei (131919)

“…<p>(A) Heatmap representation of genes identified by SAM analysis with significantly (FDR<1%) increased (73 genes) or decreased (13 genes) expression in xenografts with GATA6 mRNA levels above the mean. …”

Addition of 2-DG sequesters cholesterol from the cell membrane. by Charles A. Coomer (8479434)

“…<p>A.) Representative images depicting filipin mean fluorescence intensity per cell indicating two-hour incubation of increasing concentrations of 2-DG decreases surface cholesterol in TZM-bl cells; scale bar 50 μm. …”

Hunger and inebriation state influence social behaviour. by Geraldine A. Wright (179571)

“…(A–C) Antennation was greatest at the start of the observation, and gradually decreased. …”

Extracellular matrix-induced myelin sheet formation by oligodendrocytes requires Scribble. by Andrew A. Jarjour (343100)

“…D; Culturing oligodendrocytes on PDL-MG increased the proportion of cells exuding myelin-like membrane sheets (arrows in A). While Scribble knockdown in oligodendrocytes cultured on PDL did not affect the proportion of cells with membrane sheets, the percentage of cells with membrane sheets (arrows in B) was significantly decreased on PDL-MG. …”

Overexpressed human α-synuclein disrupted brain mitochondrial functions. by Theodore A. Sarafian (366402)

“…All values are expressed as mean ± Standard Error of Mean (SEM). However, Bonferroni post-hoc analyses showed no difference in membrane potential between brain regions [F (2,52) = 0.205, P = 0.815]. …”

Psychometric functions for the power-function transducer with nonzero pedestal. by Keith A. May (350981)

“…Across panels (right-to-left), we see a demonstration of the effect proved in Theorem 3, whereby, with a nonzero pedestal, all psychometric functions converge towards that for a linear transducer as the discrimination threshold decreases (in this case, since we are plotting psychometric functions for Gaussian noise, the functions converge towards the pure noise CDF of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074815#pone-0074815-g004" target="_blank">Figure 4B</a> as the Weber fraction decreases).…”

Enhanced High-Temperature Thermoelectric Performance of Yb_{14–<i>x</i>}Ca_<i>x</i>MnSb₁₁ by Catherine A. Uvarov (2064610)

“…The resulting lower density is beneficial from a device manufacturing perspective where there is often a trade-off with the specific power per kilogram. …”

Transcript and protein expression levels of cathepsin B (A, C), cathepsin D (B, D) and β-glucorinidase (E, F) in MS and MS9II cells. by Yanlin Wang (110566)

“…<p>Histograms showing decreased levels of C<i>tsb</i> mRNA (A) and <i>Ctsd</i> mRNA (B), but increased levels of <i>Gusb</i> mRNA (E) in MS9II cells compared to MS cells. …”

Transcript and protein expression levels of IGF-II receptor (A, B), IGF-II (C, E) and APP (D, F) in MS and MS9II cells. by Yanlin Wang (110566)

“…<p>Increased levels and expression of IGF-II receptor in MS9II <i>vs</i> MS cells are validated using Western blotting and immunofluorescence staining respectively (A, B). Histograms showing decreased level of <i>Igf2</i> mRNA (C) and increased level of <i>App</i> mRNA in MS9II cells compared to MS cells as obtained using AD-PCR-Array. …”

Table_1_Impact of Drug Safety Warnings and Cost-Sharing Policies on Osteoporosis Drug Utilization in Spain: A Major Reduction But With the Persistence of Over and Underuse. Data Fr... by Isabel Hurtado-Navarro (6036284)

“…</p><p>Patients and Methods: We constructed a monthly series of osteoporosis drug consumption for 2009–2015 from the ESOSVAL cohort (n = 11,035; women: 48%; mean age: 65 years old) and used interrupted time series and segmented linear regression models to assess changes in osteoporosis drug utilization while controlling for previous levels and trends after three natural intervention dates: the issue of the Spanish Agency for Drugs and Medical Products (AEMPS) Osteonecrosis Jaw Warning (Sept 2009), the AEMPS Atypical femur Fracture Warning (Apr 2011), and the modification of the cost-sharing scheme (Jul 2012).…”

Trial design, PPD distribution and group characteristics. by Margherita Coccia (5005985)

Relative expression (RE) and induction of BRCA1 and PCNA after cisplatin treatment in melanocytes and melanoma. by Nikola A. Bowden (441732)

“…<p>A) RE of BRCA1 and PCNA at 0, 6, 24 h after cisplatin treatment in melanoma and melanocyte cell lines. …”

Multiple sensory neurons influence the body size of <i>bbs</i> mutants. by Calvin A. Mok (201207)

“…(C–D) A model for ciliary and cGMP-mediated body size regulation. …”

Identification of the class of mediators present in the hvKP1 generated conditioned minimal medium and ascites that enhance the growth and/or survival of hvKP1. by Thomas A. Russo (188770)

“…<p>The growth of hvKP1 was assessed at 0, 3, 6, and 24 hours in human ascites (batch 1). <u>Panel A</u>: Ascites was not supplemented (unconditioned) or supplemented with: 1) 5% hvKP1-generated conditioned (cond) ascites (batch 1) or 2) 50% conditioned ascites generated from the <i>E. coli</i> laboratory strain BW25113 and isogenic derivatives deficient in the production of enterobactin (BW25113Δ<i>entB</i> (CGSC#8704), BW25113Δ<i>entC</i> (CGSC#8702)), AI-2 molecules (BW25113Δ<i>luxS</i> (CGSC#10100)), and indole (BW25113Δ<i>tnaA</i> (CGSC#8309)) (batch 1). …”

Disruption of <i>TgPHIL1</i> Alters Specific Parameters of <i>Toxoplasma gondii</i> Motility Measured in a Quantitative, Three-Dimensional Live Motility Assay by Jacqueline M. Leung (120235)

“…Methods developed for quantitative analysis of motility parameters along the smoothed trajectories demonstrate a complex but periodic pattern of motility with mean and maximum velocities of 0.58±0.07 µm/s and 2.01±0.17 µm/s, respectively. …”

Supplementary Material for: The Progression of Stargardt Disease (ProgStar) as determined by spectral-domain optical coherence tomography over a 24-month period (ProgStar Report No... by Strauss R.W. (5446388)

“…Results: Statistically significant decreases of all outer retinal layers (RPE, OS, IS, and ONL) could be observed over a 24-month period both in decline of mean retinal thickness and intact area (p<.0001, respectively); whereas the inner retina showed an increase of retinal thickness in the central subfield and inner ring and remained unchanged in the outer ring. …”

Determination of air pollution-related biomarkers of exposure in urine of travellers between Germany and China using liquid chromatographic and liquid chromatographic-mass spectrom... by Xiao Wu (158273)

“…</p> <p><b>Materials:</b> Robust LC and LC-MS/MS methods were established for the determination of biomarkers including 8-hydroxy-2′-deoxyguanosine, malondialdehyde, F_2α-isoprostanes and hydroxylated polycyclic aromatic hydrocarbons. As a pilot study, nine volunteers travelled from Germany (mean daily concentration of PM_2.5: 21 μg/m³) to China (mean daily concentration of PM_2.5: 108 μg/m³). …”