Specific knock-down of HIF-1α in MSPCs but not in ECFCs inhibits vessel formation <i>in vivo</i>. by Nicole A. Hofmann (138477)

“…(<b>C</b>) Microvessel density was quantified in 200x magnifications of HE stained Matrigel plug sections by ImageJ counting red blood cell filled vessel structures. A significantly decreased capacity to form perfused vessels was found in implants containing shHIF-1α transfected MSPCs compared to untreated co-transplants. …”

Coordinated polarity induced by high flow triggers vessel regression. by Claudio A. Franco (124909)

“…<p><b>A,</b> Overview of the axial polarization pattern of endothelial cells in a WT P6 retina vascular network labeled for endothelial cell nuclei (Erg), lumen (ICAM2), and Golgi (Golph4), and corresponding image segmentation of the vascular plexus in (a), highlighting the lumen of blood vessels (grey), and the axial polarity of all endothelial cells (red arrows). …”

Scaling of Convex Hull Volume to Body Mass in Modern Primates, Non-Primate Mammals and Birds by Charlotte A. Brassey (499316)

“…<div><p>The volumetric method of ‘convex hulling’ has recently been put forward as a mass prediction technique for fossil vertebrates. …”

DataSheet1_Conservation status and historical relatedness of South African communal indigenous goat populations using a genome-wide single-nucleotide polymorphism marker.docx by T. C. Chokoe (13217025)

“…The genomes of KZN and LP share a common origin but have substantial admixture from the EC and NW populations. …”

Data_Sheet_1_Effects of Nutrient Management Scenarios on Marine Eutrophication Indicators: A Pan-European, Multi-Model Assessment in Support of the Marine Strategy Framework Direct... by René Friedland (3934781)

“…Applying a model ensemble enabled us to obtain highly robust and consistent model results, substantially decreasing uncertainties in the scenario outcome.…”

DataSheet_1_Whole-gland high-intensity focused ultrasound ablation and transurethral resection of the prostate in the patients with prostate cancer: A systematic review and meta-an... by Yang Pan (337821)

“…Background<p>We aimed to conduct a systematic review and meta-analysis of studies reporting functional and oncologic outcomes of combining whole-gland high-intensity focused ultrasound ablation (HIFU) with transurethral resection of the prostate (TURP) in prostate cancer (PCa) patients.…”

Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine: A Randomized, Double-Blind Phase III Trial in African Children and Adolescents with Uncomplicated <em>Plasmodium f... by Zul Premji (215008)

“…Adequate clinical and parasitological response at Day 28 (uncorrected for reinfection) was 79% (604/765) with CDA and 83% (315/381) with AL. In patients with a G6PD-deficient genotype (94/603 [16%] hemizygous males, 22/598 [4%] homozygous females), CDA had the propensity to cause severe and clinically concerning hemoglobin decreases: the mean hemoglobin nadir was 75 g/L (95%CI 71, 79) at Day 7 versus 97 g/L (95%CI 91, 102) for AL. …”

<i>MMP-1</i> OE restores <i>5HT</i>_<i>2A</i><i>R</i>-deficient experience-dependent pruning. by Vanessa Kay Miller (19775496)

“…<i>MMP-1</i> OE restores synaptic pruning with a significant decrease of innervation volume in response to the EB odorant experience (blue, <i>n</i> = 10/condition, <i>p</i>-value = 4.43 × 10⁻¹³), which is nearly identical to the control. …”

Increased carrying capacity reduces the benefit of adaptive therapy by reducing spatial competition. by Masud M A (12219010)

“…S2A Fig shows that increasing the carrying capacity significantly decreased the TG (<i>p</i> − <i>value</i> < 0.001) from a median of 139 days to a median of 7 days. …”

Dose escalation study of ⁸⁹Zr-GSK2849330 in CHL-1 xenograft tumor bearing mice as measured ex-vivo using a Gamma Counter at 72 hours. by Hasan Alsaid (345385)

“…Data is presented as mean±SEM (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176075#pone.0176075.s002" target="_blank">S2 Table</a>).…”

Table1_A disproportionality analysis of low molecular weight heparin in the overall population and in pregnancy women using the FDA adverse event reporting system (FAERS) database.... by Huanying Xu (17813399)

“…However, despite the widespread use of LMWH in clinical indications, its adverse events (AEs) have not received substantial attention, and there is a lack of systematic and comprehensive AE studies. …”

CD14⁺ monocytes inhibit IFN-α production triggered by Ab-RSV via TLR7 in pDC. by Marcel A. Schijf (461275)

“…<p>(<b>A</b>) IFN-α production in CD14⁺ cell depleted PBMCs induced by Ab-RSV complexes, TLR9 ligand ODN 2216 and TLR7 ligand imiquimod is decreased by blocking endosomal acidification with 50nM Bafilomycin A₁. …”

Table_1_Safety and efficacy of cannabidiol-cannabidiolic acid rich hemp extract in the treatment of refractory epileptic seizures in dogs.pdf by Gabriel A. Garcia (13172817)

“…Epileptic seizure frequency decreased across the population from a mean of 8.0 ± 4.8 during placebo treatment to 5.0 ± 3.6 with CBD/CBDA-rich hemp extract (P = 0.02). …”

p0071 loss phenocopies FLCN-deficiency. by Doug A. Medvetz (300145)

“…In contrast, only 8% (n = 3, p<0.01) of the FLCN shRNA cells and 12% (n = 2, p<0.01) of the p0071 shRNA cells sheared into clusters of less than 10,000 pixels. Data in (A) and (C) are expressed as mean ± standard deviation. …”

Consequences of global and local c-di-GMP changes on <i>V</i>. by Andrew A. Bridges (1587328)

“…<p><b><i>cholerae</i> gene expression patterns.</b> Bottom panel: mean global c-di-GMP reporter outputs for the indicated strains and conditions expressed as percentage differences relative to untreated wild-type <i>V</i>. …”

C57BL/6 mice chronically infected with the <i>LiΔHSP70-II</i> showed a Th1 like response against <i>Leishmania</i>. by José Carlos Solana (4053745)

“…No statistical differences were found in the parasite burdens in the RP from week 4 to week 12 whereas a significant decrease was shown in the RFP (unpaired Student t-test). …”

MVEC:AoAF interactions are dependent on signaling through ALK5. by Rebecca A. Scott (488956)

“…(<b>F</b>) Following treatment with 1 μM A83-01, the number of total cells, MVECs, and AoAFs per mm³ was decreased compared to control cultures on day 14. …”

Supplementary materials: Real-world clinical outcomes and rationale for initiating abatacept as a first-line biologic for patients with anticitrullinated protein antibody- and rheu... by Alexandrina Balanean (20282985)

“…<b>Results:</b> Overall, 296 patients were included. Mean CDAI scores improved (decreased) by 34.0, 61.0 and 74.0% (all p < 0.001) from baseline to 3–6 months, 6–12 months and ≥12 months after abatacept initiation, respectively. …”

Long-Term Once-Daily Tiotropium Respimat® Is Well Tolerated and Maintains Efficacy over 52 Weeks in Patients with Symptomatic Asthma in Japan: A Randomised, Placebo-Controlled Stud... by Ken Ohta (727449)

“…term=NCT01340209&rank=1" target="_blank">NCT01340209</a></p></div>…”

Data_Sheet_1_A Prospective Multicenter Trial to Evaluate Urinary Metabolomics for Non-invasive Detection of Renal Allograft Rejection (PARASOL): Study Protocol and Patient Recruitm... by Miriam C. Banas (2827475)

“…<p>Background: In an earlier monocentric study, we have developed a novel non-invasive test system for the prediction of renal allograft rejection, based on the detection of a specific urine metabolite constellation. …”