Effect of down-regulated NNMT on cytochrome c releasing and caspase processing. by Jun Zhang (48506)

“…(B) and (D) shows the protein quantification of the western blot results shown in (A) and (C), respectively. Cyt c in cytosolic compartment was significantly increased, while the amount of mitochondrial Cyt c was significantly decreased in both cell lines infected with NNMT shRNA 1# and shRNA 2# compared to negative control. …”

Cerebellar nitrate/nitrite measurements after repeated ZL006 (10 mg/kg) injections (24 h, 19 h, and 1 h prior to decapitation) in Flinders Sensitive Line rats. by Sandra Tillmann (4330477)

“…<p><b>A</b>: Total nitrate/nitrite concentrations were decreased in rats treated with ZL006 compared to vehicle, *: <i>p ≤</i> .05. …”

Primary and secondary screenings identify several molecules affecting the synchrony index of MIN6 cells. by Sabine Bavamian (148288)

“…<p>(<i>A</i>) The primary screening of 1040 compounds revealed that several molecules increased or decreased the synchrony index. …”

The life cycle of intensifiers, with empirical examples. by Madison S. Krieger (4487053)

“…Once a word has “used up” its hyperbolic value, it decreases in usage and is supplanted either by a new bleached word or, frequently, by an older hyperbolic term whose loss of value has been forgotten by the current generation (a process called “recycling”, shown in blue). …”

Ectopic BIR efficiency in translocated strains where the distance between the BIR initiating loci and the telomere was modified. by Tannia Uribe-Calvillo (12902576)

“…The WT values are the same in the two graphs and represent the means of 49 independent experiments. Values for the translocated strains represent the means of three independent experiments. …”

Effects of knockdown (KD) on enhancer activity of the BAC-5.4kb genome sequence encompassing <i>Start</i>. by Kai Otsuka (10507952)

“…Each value was normalized to that of <i>Renilla</i> luciferase activity, which was derived from a co-transfected construct. Data are presented as means ± S.D. from six independent experiments. …”

Representative graphs of temporal pattern of expression for each group of chemokines: Four different temporal patterns of expression were noticed, and the chemokines were grouped a... by Pavlos Vlachogiannis (12289810)

“…<p>Representative graphs for each chemokine group are illustrated with their means and 0.95 CI for each day. More specifically, CCL4 is shown for Group A with its early peak and decreasing trend; CCL28 was the only chemokine of Group B with a significant middle peak on day 4; CXCL6 with its increasing trend and late peak is shown for Group C; and finally, CCL2 is representing Group D with stable values throughout the observation period. …”

JMJD2B stimulates differentiation of 3T3-L1 preadipocytes. by Min-Kyung Jang (3111393)

“…<p>(A) Knockdown of JMJD2B decreased differentiation of 3T3-L1 preadipocytes. …”

Fig 1 - by Adrianne N. Edwards (5646344)

“…The means and standard deviation of three independent biological replicates (A) or standard error of the means of four independent biological replicates (C) are shown. *, P < 0.01 by a Student’s <i>t-</i>test. …”

Transcriptional activity of the MR is attenuated by MS-275 but not MC1568. by Hae-Ahm Lee (787353)

“…Treatment with Aldo resulted in increased expression of <i>GILZ</i> (A) and <i>SGK-1</i> (B), which was decreased by MS-275 but not by MC1568. …”

Analysis of apoptosis and protein changes in human PDL cells under pathological cyclic strain. by Li Wang (15202)

“…Western blot analysis of RhoGDIα, caspase-3, and PARP protein levels. (a) Exposure to cyclic stretch correlates with increased levels of cleaved 19-kDa caspase-3 and 85-kDa PARP; the levels of 32-kDa procaspase-3 and 116-kDa PARP proteins remained unchanged, and the RhoGDIα level decreased. …”

Immediate and Heterogeneous Response of the LiaFSR Two-Component System of <em>Bacillus subtilis</em> to the Peptide Antibiotic Bacitracin by Sara Kesel (104013)

“…<div><h3>Background</h3><p>Two-component signal transduction systems are one means of bacteria to respond to external stimuli. …”

Fluorescent Peptide Biosensor for Probing the Relative Abundance of Cyclin-Dependent Kinases in Living Cells by Laetitia Kurzawa (201196)

“…This peptide biosensor technology affords direct and sensitive readout of CDK/cyclin complex levels, and reports on differences in complex formation when tampering with a single CDK or cyclin. CDKSENS further allows for detection of differences between different healthy and cancer cell lines, thereby enabling to distinguish cells that express high levels of these heterodimeric kinases, from cells that present decreased or defective assemblies. …”

Examples of NF-68 expression (arrows in B-G) in the MGN (B-D) and MoDG of the hippocampus (E-G) from the NC (B and E), 21D-B (C and F) and 21D-B/T (D and G) cohorts. by Xiaoping Du (284656)

“…Error bars represent standard error of the means. Scale bar = 50 µm in G for B-G, = 500 µm in A.…”

TLR4 deficiency diminished glomerular injury in DN. by Jin Ma (335456)

“…<p>WT diabetic mice showed significant glomerular injury including increased kidney to body weight ratio (A), glomerular volume (B), glomerular cellularity (C, week 24), glomerular mesangial matrix (D & E), decreased podocin staining (F) and WT1⁺ podocyte numbers (H & I) compared to non-diabetic WT controls. …”

Effects of bile acids and TNF-α on SP-B and SP-C mRNA levels and cleaved caspase-3 expression. by Wenli Yang (665248)

“…Relative to untreated cells, cells stimulated with CDCA, GW4064 and TNF-α had dose-dependent decreases in SP-B and SP-C mRNA production and a significant increase in cleaved caspase-3 protein expression. …”

Video_2_Winning the race with aging: age-related changes in gait speed and its association with cognitive performance in dogs.MP4 by Alejandra Mondino (5149391)

“…Introduction<p>In humans, gait speed is a crucial component in geriatric evaluation since decreasing speed can be a harbinger of cognitive decline and dementia. …”

Regulation of the SMN-interacting protein coilin. by Benjamin Förthmann (498522)

“…(E) Intensity correlation analyses of coilin and SMN in the nucleus of differentiated cells were performed and compared to a non-differentiated control. No change in colocalization of coilin and SMN was detected (B, C: n = 7, means ± SEM; *, p<0.05; **, p<0.01; unpaired, two tailed t-test; D: control, n = 18; 24h RA, n = 13; 72h RA, n = 20; E: control, n = 20; 24h RA, n = 15; 72h RA, n = 22).…”

<i>Ufm1</i>, <i>Ufbp1</i>and <i>Ufl1</i> expressionis induced upon ER stress. by Katleen Lemaire (225733)

“…Incubation of MIN6 or INS1 cells with ER stressors (25 µM CPA, 14h, INS1 cells; 1 µM thapsigargin (Tg), 1h, MIN6 cells) or proteasome inhibitor (100 µM MG115, 2h, INS1 cells) decreased conjugation, while incubation with a translational inhibitor (10 mg/l cycloheximide (CHX), 2h, MIN6 cells) increased the conjugate formation. * = UFM1−UFBP1 conjugate, 10 kDa = free UFM1.…”

Table_1_Determinants of Neural Plastic Changes Induced by Motor Practice.docx by Wen Dai (1607932)

“…None of the four tasks showed any temporary changes in behavior, meaning no learning occurred. Motor-evoked potential (MEP) amplitude increased only after the FG and it exhibited a positive correlation with the MEP increase after PAS25, suggesting that FG and PAS25 share at least similar plasticity mechanisms in the M1. …”