Study design and results for iTRAQ^® protocol. by Guillaume Desoubeaux (3446336)

“…<p>A—the iTRAQ^® reagent is designed as an isobaric stable tag consisting in a charged reporter group that retains charge (N,N-dimethylpiperazine), a peptide reactive group (N-hydoxy-succinimide) that is amide-linked to the N-terminus and the ε-amino side chains of all the peptides got from prior tryptic digestion, and a neutral balance portion (carbonyl) to maintain an overall mass of 305 kDa by the means of differential isotopic enrichment with ¹³C, ¹⁵N and ¹⁸O atoms. …”

Comparison of CBVs in different brain regions of WT and Katnal2-KO mice. by Ryeonghwa Kang (6793046)

“…<p>(A) Comparisons of cerebral blood volumes (CBVs) in WT and Katnal2-KO brains, as shown by the extents of decreases in fMRI signals induced by hypoxic nitrogen stimulus in different brain regions (left, relative CBVs) and the KO values normalized to WT values (right, %WT). …”

STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I by Cefan Zhou (7302203)

“…Moreover, we observed that STYK1 directly binds to the PtdIns3K-C1 complex as a homodimer. The binding with this complex was promoted by Tyr191 phosphorylation, by means of which the kinase activity of STYK1 was elevated. …”

DataSheet_1_Randomized Clinical Trial: Probiotics Alleviated Oral-Gut Microbiota Dysbiosis and Thyroid Hormone Withdrawal-Related Complications in Thyroid Cancer Patients Before Ra... by Baiqiang Lin (9860114)

“…</p>Results<p>Probiotics alleviated lack of energy, constipation, weight gain, and dry mouth and decreased the levels of fecal/serum LPS and plasma lipid indicators (total cholesterol, triglycerides, low-density lipoprotein, and apolipoprotein A) (P < 0.05). …”

Thermal Conductivity and Mechanical Properties of As-Cast and As-Extruded Mg-Zn-Mn Alloys by Hechao Li (8048690)

“….%) alloys were prepared by means of medium-frequency induction-heating technique and extrusion process, respectively. …”

Duration-dependent changes in CREB phosphorylation during ramelteon treatment and after washout. by Keiji Nishiyama (596968)

“…<p>(A) INS-1 cells were treated with ramelteon (10 nM) for 2, 4, 8, or 14 h. …”

miR-338 inhibits gastric cancer cell migration, invasion and proliferation, and it promotes apoptosis. by Yang Peng (486260)

“…<p>(A) The miR-338 expression was significantly increased in gastric cancer cells after infection with LV-hsa-mir-338. …”

Epidemiological characterization of reported cases of brucellosis in cattle in the western region of the state of Santa Catarina, Brazil by Fabricio Bernardi (10440834)

“…The prevalence of the disease was evaluated in cattle and herds by means of temporal trend analysis and spatial distribution. …”

8,9-Epoxyeicosatrienoic Acid Inhibits Antibody Production of B Lymphocytes in Mice by Yanxiang Gao (154594)

“…We examined the role of EETs on antibody production of splenic B cells from C57BL/6 and apolipoprotein E-deficient (ApoE−/−) mice by means of ELISA. Of the 4 EET regioisomers, 8,9-EET decreased basal and activation-induced B cell antibody secretion. …”

Serum level of ALT and AST. by Peter Onody (50458)

“…<p>Ischemic-reperfusion injury of the liver led to an increase in serum activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).A: Serum levels of ALT significantly decreased in the levosimendan pretreated groups (L_E, L_L) compared to the corresponding IR groups (IR_L, IR_E) B: Raised AST activity in the “late” IR group (IR_L) were significantly higher than in the “early” IR group (IR_E). …”

Behavioral tests for depression-like behavior in rats. by Shujiao Chen (450992)

“…<p>A. Results of the sucrose consumption test. Sucrose intake was significantly decreased in the UCMS without CSS group compared with that in the ACON without CSS groups (<i>p</i><0.001). …”

Inhibition of MMP-9 secretion and activity and intracellular accumulation of MMP-9 in WIN-treated osteoclasts, but not in microglia. by Svantje Tauber (121637)

“…<p>(a) Western blot analysis of cell lysates (MMP-9 cellular) and conditioned medium (MMP-9 secreted). using anti-MMP-9-antibody and MMP-9-activity ELISA of conditioned medium (bar chart) from osteoclasts. …”

Chop expression is upregulated in JunB knockdown and cytokine-treated cells. by Esteban N. Gurzov (185104)

“…<p>(A) RT-PCR of INS-1E cells transfected with control or JunB siRNAs and treated with cytokines. …”

Willin antagonizes some of the genes regulated by YAP in sciatic nerve fibroblasts. by Susana Moleirinho (400574)

Acute response of refeeding in tambaqui submitted to long-term fasting by Renata Franco dos SANTOS (12657971)

“…<div><p>ABSTRACT This study aimed evaluate energetic mobilization in tambaqui submitted to fasting, after a one-day refeeding. 120 tambaqui juveniles were distributed in 12 310L polyethylene boxes. …”

Heterozygous <i>Atg7</i> knockout in striatal DRD2 neurons. by Li-Fang Wang (188178)

“…<p><b>(A) Representative images of ATG7 immunoreactive DRD2 neurons.…”

The effects of C3 deficiency on inflammation and survival after LPS/D-GalN injection. by Shihui Sun (180042)

“…<p>(A) The response patterns to different ALT concentrations in C3^−/− and wt mice (n = 4–5). …”

Response of hepcidin transcript levels to serum deprivation and protein kinase inhibition. by Melanie Volke (369151)

“…<p>(<b>A</b>) Serum withdrawal rapidly decreased hepcidin transcript levels in Huh7 cells. …”

The sequence between nt. 626/640 mediates both TPA-dependent activation and the negative regulation by T3/TR. by Hiroko Misawa (335240)

“…<p>A. Schematic representation of pBL-FFL-CAT5 (WT) and its mutants, MA, MB, MC, and MD. …”

Effect of ET-1 on glucose uptake in HIF-1α-silenced astrocytes. by José Carlos Valle-Casuso (181382)

“…After 48 h, astrocytes were incubated in the absence (control, C) or presence of 0.1 µM ET-1 for 24 h. <b>A</b>) HIF-1α, Hx-1, GLUT-3, Hx-2, GLUT-1 and GAPDH Western blots and quantification. …”