Properties of acetylcholine-induced [Ca²⁺]i elevation in SH-SY5Y cells. by Tamayo Takahashi (9706873)

“…Compared with the outcome of acetylcholine treatment alone, the [Ca²⁺]i was steeply elevated but was quickly decreased. In both (A) and (B), a representative of 5 independent trials is shown. …”

Image_1_PKM2 Interacts With the Cdk1-CyclinB Complex to Facilitate Cell Cycle Progression in Gliomas.tiff by Shigeo Ohba (410801)

“…Moreover, PKM2 knock-down decreased Cdk1 activity while introducing a constitutively active Cdk1 reversed the effects of PKM2 knock-down on cell cycle progression. …”

pX interacts directly with the Bro1 domain of ALIX. by Takayoshi Shirasaki (10098660)

“…Competitor peptides, representing ExpD, the Y800A ExpD mutant, and the C-terminus of CHMP4 [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010543#ppat.1010543.ref044" target="_blank">44</a>] (<i>top</i>) were added to the mixture at molar ratios decreasing from 1 to 0.125 relative to the biotin-tagged peptide. …”

Implementing advance care planning in routine nursing home care: The development of the theory-based ACP+ program by Joni Gilissen (7512863)

“…</p><p>Methods</p><p>The work was carried out by means of 1) operationalization of key intervention components–identified as part of a previously developed theory on how advance care planning is expected to lead to its desired outcomes in nursing homes–into specific activities and materials, through expert discussions and review of existing advance care planning programs; 2) evaluation of feasibility and acceptability of the program through interviews with nursing home management and staff and expert revisions; and 3) standardized description of the final program according to the TIDieR checklist. …”

GNB1 protein contributed to viral particle release triggered by H9N2 virus-derived M1 protein. by Fangtao Li (5730533)

“…(F–J) GNB1 knockdown decreased rM14:M-H9N2 virus replication in A549 cells. …”

Health-related quality of life of patients with prostate cancer initiating GnRH agonist therapy: the PRISME study by François Rozet (20138169)

“…Most patients with prostate cancer are over the age of 60 years, but elderly patients are often excluded from clinical trials, meaning that we lack data about them. This study assessed if there was a link between age and health-related quality of life in men with advanced prostate cancer treated with hormone therapy. …”

In <i>Drosophila</i> activity of the DSK receptor (CCKLR-17D3) is necessary for PER. by Di Guo (718480)

“…<p>(<b>A and B</b>) Refeeding after 24h starvation decreases <i>17d3</i> mRNA transcript in the labellum and proleg tarsi. …”

Assessment of Full-Scale N₂O Emission Characteristics and Testing of Control Concepts in an Activated Sludge Wastewater Treatment Plant with Alternating Aerobic and Anox... by Xueming Chen (1564720)

“…Therefore, properly extending the length of anoxic phase could serve as a potential control means to regulate N₂O accumulation in the anoxic phase. …”

Data_Sheet_1_Owned dog population size and ownership patterns in Costa Rica.pdf by D. T. Tyler Flockhart (8142144)

“…The probability of owning a dog was highest on farms and lowest in single family dwellings without a yard, higher among respondents that owned their homes and decreasing with increasing human population density The total number of owned dogs in Costa Rica was estimated to be 2,222,032 (95% confidence intervals: 1,981,497–2,503,751). …”

DataSheet_1_Histone lysine-specific demethylase 1 regulates the proliferation of hemocytes in the oyster Crassostrea gigas.docx by Xiaoyu Gu (576058)

“…</p>Methods<p>We conducted a comprehensive analysis by various means to verify the function of CgLSD1 in hematopoietic process, including quantitative real-time PCR (qRT-PCR) analysis, western blot analysis, immunofluorescence assay, RNA interference (RNAi) and flow cytometry.…”

<i>dSERT</i>^<i>16</i> mutants exhibit increased sleep behavior and changes in sleep architecture. by Elizabeth M. Knapp (14149819)

“…<p>Sleep was separately recorded with single-beam and multibeam monitors. (A) Quantification of total sleep in <i>w</i>^<i>1118</i> controls (grey) and <i>dSERT</i>^<i>16</i> homozygous mutants (red). …”

S1 Data - by Dénes Pauka (16955686)

“…Comparing the histological groups by the measured parameters (<i>F</i>_max, <i>L</i>_max, <i>F</i>_break, <i>L</i>_break) showed a significant difference in the means (p<0.001, p = 0.003, p<0.001 respectively). …”

Model validation against known CiPA compounds effects on whole-organ function. by Stefano Longobardi (10654047)

The recruitment of Paf1C to the <i>frq</i> ORF is regulated by the WCC activity. by Mengmeng Zhou (9197699)

“…<p>(A) The enrichment of PAF-1 (Left) or RTF-1 (Right) at the <i>frq</i> ORF middle region significantly decreased in <i>wc-2</i>^<i>KO</i> strain at DD14. …”

Techniques, challenges, and opportunities in mobile thematic map design for data journalism by Lily Houtman (21008595)

“…This work shows that news cartographers solve mobile thematic map design challenges through iterative design processes that draw from years of expertise, not a strict set of guidelines.</p> <p></p><p>News cartographers currently design mobile thematic maps based on generalized best practices, but are uncertain what choices do and do not work for their readers</p><p>Many news cartographers design maps simultaneously for desktop and mobile, rather than prioritizing one over the other</p><p>News cartographers are decreasing their use of interactive maps, given that they expect news readers want to consume information as fast as possible</p><p>News maps are produced under time constraints that can be limiting on creativity and novelty, and without time for user testing</p><p></p> <p>News cartographers currently design mobile thematic maps based on generalized best practices, but are uncertain what choices do and do not work for their readers</p> <p>Many news cartographers design maps simultaneously for desktop and mobile, rather than prioritizing one over the other</p> <p>News cartographers are decreasing their use of interactive maps, given that they expect news readers want to consume information as fast as possible</p> <p>News maps are produced under time constraints that can be limiting on creativity and novelty, and without time for user testing</p>…”

Data_Sheet_1_Access to care through telehealth among U.S. Medicare beneficiaries in the wake of the COVID-19 pandemic.PDF by Min Lu (238723)

“…</p>Findings<p>The rate of reported forgone medical care because of COVID-19 decreased largely (22.89–3.31%) with a small increase in telehealth coverage (56.24–61.84%) from the week of June 7, 2020, to the week of April 4 to 25, 2021. …”

Data_Sheet_1_2-Keto-L-Gulonic Acid Improved the Salt Stress Resistance of Non-heading Chinese Cabbage by Increasing L-Ascorbic Acid Accumulation.PDF by Mingfu Gao (11644831)

“…<p>Salt stress has long been a prominent obstacle that restricts crop growth, and increasing the L-ascorbic acid (ASA) content of crops is an effective means of alleviating this stress. 2-Keto-L-gulonic acid (2KGA) is a precursor used in industrial ASA production as well as an ASA degradation product in plants. …”

Image_1_Overexpression of the Transcription Factor AtLEC1 Significantly Improved the Lipid Content of Chlorella ellipsoidea.pdf by Xiao Liu (65413)

“…By comparing the differentially expressed genes (DEGs) regulated by AtLEC1 in C. ellipsoidea and Arabidopsis, we observed that approximately 59% (95/160) of the genes related to lipid metabolism were upregulated in AtLEC1 transgenic Chlorella. Our research provides a means of increasing lipid content by introducing exogenous TF and presents a possible mechanism of AtLEC1 regulation of lipid accumulation in C. ellipsoidea.…”

Table_1_Targeted Metabolomics Shows That the Level of Glutamine, Kynurenine, Acyl-Carnitines and Lysophosphatidylcholines Is Significantly Increased in the Aqueous Humor of Glaucom... by Alejandro Lillo (11666527)

“…The imbalance affects membrane components, especially those of the mitochondria, suggesting that mitochondrial abnormalities are a cause or consequence of glaucoma. The increase in glutamine in glaucoma is also relevant because it could be a means of keeping the concentration of glutamate under control, thus avoiding its potential to induce the death of neurons and retinal cells. …”

Data_Sheet_1_Targeted Metabolomics Shows That the Level of Glutamine, Kynurenine, Acyl-Carnitines and Lysophosphatidylcholines Is Significantly Increased in the Aqueous Humor of Gl... by Alejandro Lillo (11666527)

“…The imbalance affects membrane components, especially those of the mitochondria, suggesting that mitochondrial abnormalities are a cause or consequence of glaucoma. The increase in glutamine in glaucoma is also relevant because it could be a means of keeping the concentration of glutamate under control, thus avoiding its potential to induce the death of neurons and retinal cells. …”