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461
An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD and Disulfiram.
Published 2019“…From the molecular docking analysis with NAD , we observed that the interaction affinity of the NAD decreases with the impact of E504K variant. …”
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462
Estimating and decomposing changes in the White–Black homeownership gap from 2005 to 2011
Published 2015“…Our analysis shows that the housing bust did not affect the homeownership gap uniformly. In fact, we find that the gap decreased for households that were the least likely to own and remained unchanged for households that were the most likely to own, and that Black households with around a 50% probability of homeownership were especially vulnerable to the crisis. …”
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463
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464
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. …”
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465
Divergent changes of the elevational synchronicity in vegetation spring phenology in North China from 2001 to 2017 in connection with variations in chilling
Published 2021“…Specifically, SE showed a significant (p-value < .05) decreasing trend for the two southernmost mountains, indicating an increasing elevational synchronization in SOS. …”
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466
Estimation of Mechanical Properties of Copper Powder Filled Linear Low-Density Polyethylene Composites
Published 2022“…Conclusion: In line with the experimental data, we found that as we increased the volume fraction of the copper powder, the elongation and stress at break of the composites decreased, while the Young’s modulus increased.…”
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467
Quality, safety and efficiency in practice: Risk assessment and standardisation of anesthesia equipment and supplies in operating theaters of high-volume tertiary-care academic med...
Published 2019“…Background: Operating theatres (OTs) are valuable and costly resources that need to be appropriately designed and stocked for efficient, quality and safe patient care. We assessed the logistic inefficiency including the availability and location layout of necessary supplies across OTs of a high-volume tertiary-care academic medical center. …”
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468
Investigating the succession process of native desert plants over hydrocarbon-contaminated soils using remote sensing techniques
Published 2023“…We also observed that the succession process of vegetation growth over hydrocarbon-contaminated soils could be associated with vegetation growth on a clean sediment layer covering the oil layer. …”
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469
Repositioning for pressure injury prevention in adults.
Published 2020“…Positioning regimens: four trials compared different tilt positions We pooled data from two trials (252 participants) that compared a 30° tilt with a 90° tilt (random-effects; I² = 69%). …”
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470
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
Published 2018“…Here, we provide a review of the EBV epidemiology and the genetic variability of the oncogene LMP-1. …”
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471
Graph-Guided Regularized Regression of Pacific Ocean Climate Variables to Increase Predictive Skill of Southwestern U.S. Winter Precipitation
Published 2021“…We use large ensemble simulations from a climate model to construct this regularizer, reducing the structural uncertainty in the estimation. …”
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472
Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots
Published 2017“…The observed drastic differences between the hole and electron injection are consistent with a model where the hole effective mass decreases, while the gradient shell thickness increases.…”
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473
Comparative Study on Gas-Sensing Properties of 2D (MoS2, WS2)/PANI Nanocomposites-Based Sensor
Published 2022“…The bandgap of the materials decreased due to the addition of MoS2 and WS2. We also analyzed its structural, optical and morphological properties. …”
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474
VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma.
Published 2018“…We assessed the plasma level of VEGF-121 in a brain xenograft model, in human healthy controls, and in patients suffering from recurrent GB before and after bevacizumab treatment. …”
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475
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…Moreover, NHE1 transgenic mice also showed increased collagen deposition, upregulation of CD44 and phosphorylation of p90 ribosomal s6 kinase (RSK), effects that were regressed in OPN knockout mice. In conclusion, we developed an interesting comparative model of active NHE1 transgenic mouse lines which express a dilated hypertrophic phenotype expressing CD44 and phosphorylated RSK, effects which were regressed in absence of OPN.…”
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476
Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
Published 2022“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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477
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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478
Thermal and mechanical stability of microwave sintered cold compact bismuth telluride thermoelectric material
Published 2022“…The TGA-DSC results indicate a slight mass gain at 350 °C followed by a steep weight loss beyond 550 °C suggesting good thermal stability when the experimental temperature is below 350 °C. …”
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479
PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
Published 2017“…Our results uncover a very significant role for PRMT5 in GBMNS self-renewal capacity and proliferation. …”
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480