A Cell-Based Assay for RNA Synthesis by the HCV Polymerase Reveals New Insights on Mechanism of Polymerase Inhibitors and Modulation by NS5A by C. T. Ranjith-Kumar (199732)

“…The inhibition by NS5A was decreased with the removal of the transmembrane helix in NS5B. …”

Data Sheet 1_Unlocking the adaptation mechanisms of the oleaginous microalga Scenedesmus sp. BHU1 under elevated salt stress: a physiochemical, lipidomics and transcriptomics appro... by Rahul Prasad Singh (20283954)

“…<p>Microalgae are vital for their photosynthetic abilities, contributing significantly to global oxygen production, serving as a key trophic level in aquatic ecosystems, aiding in biofuel production, assisting in wastewater treatment, and facilitating the synthesis of valuable biochemicals. …”

Data_Sheet_1_σS-Mediated Stress Response Induced by Outer Membrane Perturbation Dampens Virulence in Salmonella enterica serovar Typhimurium.docx by Seul I Kim (6005195)

“…Interestingly, regardless of the defects in the outer membrane integrity, RpoS overproduction decreased transcription from the common promoter of ssrA and ssrB, which encode a two-component regulatory system for SPI-2. …”

Salvianolic acid A alleviates the renal damage in rats with chronic renal failure by Guangming Zhang (467131)

“…<div><p>Abstract Purpose: To investigate the protective effects of salvianolic acid A (SAA) on renal damage in rats with chronic renal failure (CRF). …”

Data_Sheet_1_The Alteration of Salivary Immunoglobulin A in Autism Spectrum Disorders.docx by Wuyi Gong (10837158)

“…</p><p>Results: We found that salivary IgA content was significantly decreased in patients with ASD and had a significant ASD diagnostic value. …”

Deletion of single <i>miR-1/133a</i> clusters does not cause gross morphological alterations in the heart but results in decreased ejection fraction in <i>miR-1-1/133a-2</i> mutants after TAC. by Katharina Wystub (460622)

Image_1_Japanese Encephalitis Virus Persistence in Porcine Tonsils Is Associated With a Weak Induction of the Innate Immune Response, an Absence of IFNγ mRNA Expression, and a Decreased Frequency of CD4+CD8+ Double-Positive T Cells.tif by Valerie Redant (6106304)

“…Strikingly, the persistence of JEV in tonsils was also associated with a significant decreased frequency of CD4⁺CD8⁺ double-positive T lymphocytes. …”

Image_2_Japanese Encephalitis Virus Persistence in Porcine Tonsils Is Associated With a Weak Induction of the Innate Immune Response, an Absence of IFNγ mRNA Expression, and a Decreased Frequency of CD4+CD8+ Double-Positive T Cells.tif by Valerie Redant (6106304)

“…Strikingly, the persistence of JEV in tonsils was also associated with a significant decreased frequency of CD4⁺CD8⁺ double-positive T lymphocytes. …”

Data_Sheet_1_FliW and CsrA Govern Flagellin (FliC) Synthesis and Play Pleiotropic Roles in Virulence and Physiology of Clostridioides difficile R20291.PDF by Duolong Zhu (3613781)

“…We showed that fliW deletion, csrA overexpression in R20291, and csrA complementation in R20291ΔWA (fliW-csrA codeletion mutant) dramatically decreased FliC production, but not fliC gene transcription. …”

Image 1_Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11.tif by Li Ling (424480)

“…Moreover, the combination of SAS and ¹³¹I significantly increased the MDA levels and lipid peroxidation, decreased the GSH levels, and suppressed the expression of SLC7A11 and GPX4, while SLC7A11 knockdown significantly enhanced ferroptosis-related markers in DTC cells. …”

Tumor growth after tumor challenge in C57BL/6 mice immunized with recMAGE-A3 formulated with different immunostimulants. by Catherine Gérard (564552)

“…Also, tumor growth rate was decreased in the recMAGE-A3+AS15 group, compared with the other groups (p<0.01).…”

Even a Chronic Mild Hyperglycemia Affects Membrane Fluidity and Lipoperoxidation in Placental Mitochondria in Wistar Rats by María del Consuelo Figueroa-García (832711)

“…Whereas the chronic mild hyperglycemia induced a decrease in unsaturated to saturated fatty acids ratio (U/S) in placental total tissue, the ratio increased in placental mitochondria. …”

MnTBAP treatment improves insulin-assisted glucose tolerance (IAGT) in mice fed a HFD. by Jonathan R. Brestoff (799142)

Overexpression of miR-33a, miR-149 and miR-193a-3p mimic reduced expression levels of predicted target proteins in WRO cells. by Hiroki Takeshita (161180)

“…<p>(<b>A</b>) Transfection of miR mimics (33a-m, 149-m and 193a-m) significantly increased respective miRNA expression, whereas control miR mimic (cont-m) had no such effect, as quantified by real-time quantitative RT-PCR. …”

Oxidative Stress of in-Ovo Ochratoxin A Administered during Chick Embryonic Development by MAE Elsayed (6699935)

“…<div><p>ABSTRACT The present work was carried out to study the effect of in-ovo injection of ochratoxin A (OTA) as an oxidative stress and its consequences on hepatic and kidney functions, thyroid activity, and histological examination of brain and liver in chicken embryos and subsequently in the hatching chicks. …”

Structural Rigidity and Protein Thermostability in Variants of Lipase A from <i>Bacillus subtilis</i> by Prakash Chandra Rathi (765310)

“…They have been related to differences in the temporal resolution of experiments and computations that probe atomic mobility. Here, we find a significant (<i>p</i> = 0.004) and fair (<i>R</i>² = 0.46) correlation between the structural rigidity of a well-characterized set of 16 mutants of lipase A from <i>Bacillus subtilis</i> (<i>Bs</i>LipA) and their thermodynamic thermostability. …”

Dry Priming of Maize Seeds Reduces Aluminum Stress by Berenice Kussumoto Alcântara (841346)

“…Enhanced productivity was observed for DA under Al stress after priming the seeds. Furthermore, the AsA treatment decreased the activity of oxidative stress-related enzymes in the DA genotype. …”

Clinical experience with the inactivated hepatitis A vaccine, Avaxim 80U Pediatric by Catherine Bravo (5822357)

“…Prevalence of hepatitis A is strongly correlated with socioeconomic factors, decreasing with increased socio-economic development, access to clean water and sanitation. …”

Data_Sheet_1_NsrR1, a Nitrogen Stress-Repressed sRNA, Contributes to the Regulation of nblA in Nostoc sp. PCC 7120.PDF by Isidro Álvarez-Escribano (5781266)

“…We demonstrate specific interaction between NsrR1 and the 5′-UTR of the nblA mRNA, that leads to decreased expression of nblA. …”

DataSheet1_Changes in serum uteroglobin level in type 2 diabetes mellitus patients.docx by Joung Youl Lim (18237598)

“…</p>Conclusions<p>Uteroglobin is a sensitive factor that was decreased even in prediabetes and increased upon treatment with drugs with anti-inflammatory effects. …”