Effects of Tirzepatide Versus Basal Insulins in People with Type 2 Diabetes and Different Baseline Glycemic Patterns: Post Hoc Analyses of the SURPASS-3 and SURPASS-4 Trials by Francesco Giorgino (385654)

“…Within each subgroup, HbA1c and PPG decreases were greater with tirzepatide than insulin (p<0.05). …”

Demonstration of autoantibody specificity by inhibition in ELISA. by Martin W. Laass (750429)

“…A serum with high anti-GP2 IgA level at a dilution giving an optical density (OD) of 0.8 was pre-incubated with recombinant GP2 (Isoform alpha) and tissue transglutaminase (TG) at decreasing concentrations from 0–10 μg/mL. …”

S100A6 overexpression alters the expression of β-catenin and EMT-related markers. by Xue Chen (127892)

“…(B) Real-time PCR revealed that S100A6 overexpression resulted in decreased expression of E-cadherin, and increased expression of N-cadherin and vimentin. …”

Data Sheet 1_AhR regulation of amyloid beta-induced inflammation in astrocyte cells.pdf by Emmanuel Ojo (679304)

“…This study explores how AhR affects astrocyte function in response to inflammatory stimuli, with emphasis on Aβ.</p>Methods and Results<p>In primary hippocampal astrocyte cultures from wild type (WT, C57BL6/J) or AhR germline knockout (AhRKO) mice, pretreatment with the AhR agonist, 6-Formylindolo[3,2-b] carbazole (FICZ), attenuated Aβ-induction of reactive astrocyte development, characterized by decreased astrocyte complement C3 expression and decreased proinflammatory cytokine release. …”

Macrophyte growth forms shift along the trophic gradient of lakes by Willem Kaijser (12872371)

“…Based on the RF models, the abundance of Characeae decreased abruptly at 5–13 µg L⁻¹ Chl-<i>a</i>, whereas canopy-forming species showed a monotonous and slight unimodal decreasing response at 35–103 µg L⁻¹ Chl-<i>a</i>. …”

Erratum: Atorvastatin Protects Myocardium Against Ischemia-Reperfusion Injury Through Inhibiting miR-199a-5p by Zuo Y. (4275169)

“…Upregulation and downregulation of miR-199a-5p respectively decreased and increased GSK-3β expression both in mRNA level and protein level. …”

Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-induced Retinal Dysfunction and Neurodegeneration through Rhodopsin by Jianglei Chen (9757280)

“…Interphotoreceptor retinol-binding protein (IRBP) is a visual cycle protein and important for 11-<i>cis</i>-retinal generation. …”

S100 Calcium-Binding Protein A6 Promotes Epithelial-Mesenchymal Transition through β-Catenin in Pancreatic Cancer Cell Line by Xue Chen (127892)

“…Specifically, expression of E-cadherin was increased, whereas expression of N-cadherin and vimentin was decreased. Finally, we demonstrated that S100A6 alters the expression of EMT-related markers via β-catenin activation. …”

(a) XRD patterns of Ti alloy after charging for various conditions; (b) section of XRD patterns in (a) ranging from 53°to 63°. by Yequan Chen (4743963)

Data Sheet 1_Impaired sensitivity to thyroid hormones is associated with high lipoprotein(a) level in euthyroid patients with type 2 diabetes mellitus.docx by Luojing Zhong (21599015)

“…By contrast,the aOR(95% CI) for high Lp(a) level was decreased with rising FT3/FT4 ratio quartiles (P<0.05). …”

Walking through a narrow opening improves collision avoidance behavior in a patient with stroke and unilateral spatial neglect: an ABA single-case design by Daisuke Muroi (3684850)

“…<p>We investigated the effect of a 3-week intervention—wherein a patient with unilateral spatial neglect walks through a narrow opening while entering from the contralesional side—to improve walking ability or ADL. …”

Effects of ESE-16 on ROS and lysosomal activity in MDA-MB-231, MCF-7 and MCF-12A cells after 24 h exposure. by Barend Andre Stander (108706)

“…<p>Relative mean fluorescence intensity of DCF (FL1) (A) hydroethidine (FL3) (B) in MCF-7, MDA-MB-231 and MCF-12A cells exposed to ESE-16 (200 nM). …”

Assessing car-sharing as a circular economy strategy: the case of Taiwan by Hsiu-Ching Shih (2124013)

“…This study aims to develop a methodology that combines linear programming and a computable general equilibrium model to assess how consumer behavior affects the potential of car-sharing to replace private car usage in densely populated cities such as those in Taiwan and how the resultant potential influences the repercussion effect across industries. …”

A novel SNP of <i>MYO1A</i> gene associated with heat-tolerance in Chinese cattle by Yanhong Cao (428443)

“…Further analysis showed that frequency of wild allele A decreased gradually from northern cattle to southern cattle, whereas frequency of mutant type allele G showed the opposite pattern, which was consistent with the distribution of various climatic conditions of China. …”

Integrin and RNF31 binding to SHARPIN are mutually exclusive. by Nicola De Franceschi (4518478)

“…(B) Co-immunoprecipitation of endogenous SHARPIN, RNF31 and ITGAL from Jurkat cells (a GFP antibody was used as negative control). (C) Pull-down of GFP-SHARPIN from HEK293 cells demonstrated that cells in suspension show decreased RNF31-SHARPIN interaction compared to adherent cells (n = 4). …”

The Self-Limiting Dynamics of TGF-β Signaling <i>In Silico</i> and <i>In Vitro</i>, with Negative Feedback through PPM1A Upregulation by Junjie Wang (172690)

“…We then proposed a negative feedback loop with upregulation of the phosphatase PPM1A. …”

Table_6_Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells.XLS by Jing Li (10611)

“…Furthermore, IL-17A can partially facilitate A549 cell infection by the PR8 strain and PR8-infected IL-17A knock-out mice consistently exhibited decreased weight loss and reduced lung immunopathology, as compared to controls. …”

Table_6_Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells.XLS by Jing Li (10611)

“…Furthermore, IL-17A can partially facilitate A549 cell infection by the PR8 strain and PR8-infected IL-17A knock-out mice consistently exhibited decreased weight loss and reduced lung immunopathology, as compared to controls. …”

Image_1_Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells.TIF by Jing Li (10611)

“…Furthermore, IL-17A can partially facilitate A549 cell infection by the PR8 strain and PR8-infected IL-17A knock-out mice consistently exhibited decreased weight loss and reduced lung immunopathology, as compared to controls. …”

Table_4_Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells.DOCX by Jing Li (10611)

“…Furthermore, IL-17A can partially facilitate A549 cell infection by the PR8 strain and PR8-infected IL-17A knock-out mice consistently exhibited decreased weight loss and reduced lung immunopathology, as compared to controls. …”