Optimizing lornoxicam-loaded poly(lactic-co-glycolic acid) and (polyethylene glycol) nanoparticles for transdermal delivery: <i>ex vivo</i>/<i>in vivo</i> inflammation evaluation by Rubina Qaiser (8761773)

“…<b>Materials & methods:</b> Synthesized nanoparticles were subjected to <i>in vitro</i> characterization, <i>ex vivo</i> permeation studies, and acute oral toxicity analysis post-incorporation into the gel using a S/O/W double emulsion solvent. …”

FSH stimulation of P₄ and E₂ is reduced with co-incubation of WNT3A and FSH. by Andrea D. Stapp (510298)

“…FSH stimulation of E₂ was markedly decreased (<i>P</i>  =  0.05) in cells exposed to both FSH plus 500 ng/mL WNT3A. …”

Supporting information file. by Sergio Saia (529861)

Insulin inhibited miR-99a expression, but induced glucose consumption and lactate production, and increased the expression of mTOR, HIF-1α and PKM2 in HepG2 and HL7702 cells. by Wei Li (7081)

“…Relative miR-99a expression levels were normalized to U6. Data were presented by mean±SE (n = 3). **, indicates significant decrease compared to the cells without insulin treatment (p<0.01). …”

Exemplar proxy FC computed from eigenvectors of the structural connectivity matrix <i>w</i>_<i>ij</i>, computed by taking the outer product of an eigenvector with itself. by Michael Forrester (6165878)

Complete blood count (CBC) values of dog samples. by Chanon Fa-ngoen (18121319)

“…No significant difference in seroprevalence for the three serogroups was observed in any of the 64 districts sampled. The mean hematocrit level significantly decreased in seropositive dogs (P<0.05). …”

Complete blood count (CBC) values of cat samples. by Chanon Fa-ngoen (18121319)

“…No significant difference in seroprevalence for the three serogroups was observed in any of the 64 districts sampled. The mean hematocrit level significantly decreased in seropositive dogs (P<0.05). …”

Changes in oak (<i>Quercus robur</i>) photosynthesis after winter moth (<i>Operophtera brumata</i>) herbivory are not explained by changes in chemical or structural leaf traits - F... by Kristiina Visakorpi (8356917)

Progression of hearing loss based on SIOP grade. by E. Clemens (6335312)

Progression of hearing loss based on Chang grade. by E. Clemens (6335312)

Progression of hearing loss based on Muenster grade. by E. Clemens (6335312)

Progression of hearing loss based on Brock grade. by E. Clemens (6335312)

<i>In Situ</i> Characterization of Dehydration during Ion Transport in Polymeric Nanochannels by Chenghai Lu (11330281)

“…The transport of hydrated ions across nanochannels is central to biological systems and membrane-based applications, yet little is known about their hydrated structure during transport due to the absence of <i>in situ</i> characterization techniques. Herein, we report experimentally resolved ion dehydration during transmembrane transport using modified <i>in situ</i> liquid ToF-SIMS in combination with MD simulations for a mechanistic reasoning. …”

Effects of HWHF on insulin secretion from (A & B) BRIN-BD11 cells and (C) pancreatic islets, (D) protein glycation, (E) insulin release in the presence of established stimulators o... by Prawej Ansari (12191266)

DLL4 is a direct target of miR-30a. by Qing Bo Huang (427668)

“…Relative mRNA expression of DLL4 was decreased by miR-30a. (E) Western blotting showed that DLL4 was decreased by miR-30a after 48 hours of transfection. …”

Laboratory confirmed hospitalized cases. by Jessica Hartman Jacobs (145665)

“…For example, log(0.6) corresponds to the fixed bandwidth of 4 used to create Figures <i>A</i> and <i>B</i> and a black horizontal line identifies this bandwidth. …”

Laboratory confirmed cases that were not hospitalized. by Jessica Hartman Jacobs (145665)

“…The grid lines correspond to 1 year of age intervals. <b>D</b> SiZer plot of the second derivative of the weighted risk ratio by age, where the symbols are as described for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042328#pone-0042328-g002" target="_blank">Figure <i>2C</i></a>.…”

Heat map of 20 metabolites selected by the PLS-DA VIP score > 1.5 across 6 months to 4 years of age. by Chih-Yung Chiu (571865)

“…The changes of x-fold standard deviation from the overall mean concentration for different years of age are shown in a color-coded way. …”

S1 File - by Kazuyuki Hirooka (2635717)

“…<div><p>Purpose</p><p>Optic nerve head (ONH) blood flow decrease without changes in intraocular pressure in a possible rat model of retinal ganglion cell loss by systemic administration of aldosterone. …”

Description of included studies. by Yong Luo (138733)

“…The forest plot outcome indicated that CPAP therapy would lower the TNF-α levels in OSAHS patients, with a weighted mean difference (WMD) of 1.08 (95% CI: 0.62–1.55; <i>P</i> < 0.001) based on the REM since there is highly significant heterogeneity (<i>I</i>^<i>2</i> = 90%) among the studies. …”