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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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224861
Presentation_1_Leptin-Mediated Sympathoexcitation in Obese Rats: Role for Neuron–Astrocyte Crosstalk in the Arcuate Nucleus.pptx
Published 2019“…Moreover, the expression of the leptin receptor in the ARCN of HFD-fed rats was significantly increased compared to rats fed a control diet. Immunohistochemistry analysis revealed leptin receptor localization from both neurons and astrocytes of the ARCN. …”
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224862
Deficiency of UBQLN1 aggravates idiopathic pulmonary fibrosis.
Published 2023“…<p>(A) UBQLN1 transcription level decreased in human lungs of IPF patients. …”
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224863
Table 8_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx
Published 2025“…However, the specific effects of different drainage durations on soil microorganisms and metabolites remain unclear. This study adopted a multi-omics research method. After nontargeted metabolomics analysis of lipids as the main metabolite, microbial diversity analysis and lipidomics analysis were conducted to determine the main influencing factors. …”
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224864
DataSheet_3_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx
Published 2021“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”
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224865
Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx
Published 2025“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. …”
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224866
Image_1_Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.tif
Published 2023“…</p>Results and Discussion<p>All tested fluoroquinolones in 2D culture decreased the viability of both tested cell lines in a dose- and timedependent manner. …”
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224867
Reduction of myc-Nkx2.5 protein in cells treated with <i>O</i>-GlcNAcase inhibotirs.
Published 2013“…<p>(A) Immunoblotting of myc-Nkx2.5 and <i>O</i>-GlycNAcylated proteins in myc-Nkx2.5-transfected HEK293 cells in the presence or absence of 3 mM streptozotocine (STZ). …”
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224868
Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…<p>Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, inflammation, and hepatocyte damage. A Western-style diet characterized by excessive n-6 polyunsaturated fatty acid (n-6 PUFA) intake, which is metabolized to pro-inflammatory arachidonic acids (AAs), might contribute to the exacerbation of NASH. …”
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224869
Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf
Published 2025“…This knowledge could be useful in controlled environment agriculture and indoor cultivation (i.e., vertical farming) as well as in space research on potato, as this crop is a candidate for plant-based regenerative systems for long-term missions.…”
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224870
Image_3_Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways...
Published 2018“…Meanwhile, the elevated expression levels of pp65, TLR4, p-STAT3, and p-JAK2 were significantly decreased after treatment. Results suggested that CP would be a potential prebiotics for alleviation of TNBS-induced colitis. …”
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224871
Seed and peel essential oils obtained from <i>Campomanesia adamantium</i> fruit inhibit inflammatory and pain parameters in rodents
Published 2017“…No clinical signs of toxicity have been observed in animals. It was observed a significant decreased (<i>P</i><0.01) in leukocyte migration at the dose of 300 mg/kg of EOP and EOS, with maximal inhibition of 89±3% for EOP and 80±6% for EOS. …”
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224872
Rotundifolone-induced Ca<sup>2+</sup> transient in myocytes depend of extracellular Ca<sup>2+</sup>.
Published 2015“…<p>(A) Representative recording of the Ca<sup>2+</sup> signals induced by rotundifolone (10<sup>−3</sup> and 3x10<sup>-3</sup> M) in freshly dispersed vascular smooth muscle cells from rat superior mesenteric artery. …”
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224873
Presentation_1_Salvianolic Acid B and Ginsenoside Re Synergistically Protect Against Ox-LDL-Induced Endothelial Apoptosis Through the Antioxidative and Antiinflammatory Mechanisms....
Published 2018“…Furthermore, the composition of SR was optimized through central composite design with response surface methodology. SR with a composition of 60 μg/mL of SalB and 120 μg/mL of Re exerted the optimal protective effect. …”
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224874
Data_Sheet_2_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP
Published 2022“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”
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224875
DataSheet_8_SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals.zip
Published 2022“…</p>Results<p>Increased estrogen-estrogen receptor (ER) α signaling and decreased progesterone receptor isoform B (PRB) expression synergistically led to a hypo-autophagy state in eESCs, which further inhibited the apoptosis of eESCs. …”
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224876
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224877
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage
Published 2023“…Ferroptosis, a form of regulatory non-apoptotic cell death driven by iron-dependent lipid peroxidation, accounts for more than 80% of the total types of neuronal death in the acute phase of intracerebral hemorrhage (ICH). …”
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224878
Image_1_Immunogenicity of SARS-CoV-2 mRNA intramuscular vaccination in patients with muscular disorders.jpeg
Published 2023“…</p>Conclusion<p>Intensity and latency of antibody response were suppressed in patients with MDs. Although MDs may be a key contributor in predicting the antibody response to SARS-CoV-2 vaccination, SARS-CoV-2 immunization in MDs needs extensive research.…”
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224879
Immunoglobulin heavy light chain test quantifies clonal disease in patients with AL amyloidosis and normal serum free light chain ratio
Published 2016“…</p> <p><i>Conclusions</i>: The HLC assay has potential as a supplemental test to quantify monoclonal protein in patients with normal FLCr results.…”
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224880
DataSheet_4_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx
Published 2021“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”