Table_1_Uncovering the Resistance Mechanism of Mycobacterium tuberculosis to Rifampicin Due to RNA Polymerase H451D/Y/R Mutations From Computational Perspective.docx by Qianqian Zhang (587342)

“…In H451R mutant, the mutation causes the binding pocket change too much so that the position of rifampicin has a large movement in the binding pocket. In this study, the resistance mechanism of rifampicin at the atomic level is proposed. …”

DataSheet_1_Serum uric acid is related to liver and kidney disease and 12-year mortality risk after myocardial infarction.docx by Luc Heerkens (16954658)

“…</p>Conclusions<p>NAFLD and CKD were strongly associated, which was reflected by higher SUA concentrations. SUA was a strong predictor of 12-year mortality risk after MI.…”

Table3_Shifting Trade-offs: Finding the Sustainable Nexus of Hydropower and Environmental Flows in the San Joaquin River Watershed, California.XLSX by Ann D. Willis (11307490)

“…The functional flow strategy allocated water in a holistic approach that enhanced ecological functions in all years, but particularly in moderate and wet years. …”

datasheet2_Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing.doc by Dan-dan Xu (3766957)

“…Hence, these results provide a rationale for the therapeutic potential of the combination of SNX-2112 with shSTAT3 in esophageal cancer, and may indicate new targets for clinical intervention in human cancer.…”

Table_2_Disrupted Brain Structural Network Connection in de novo Parkinson's Disease With Rapid Eye Movement Sleep Behavior Disorder.DOCX by Amei Chen (10308410)

“…The altered Ne of right insula, left temporal pole and left middle frontal gyrus may play a key role in the pathogenesis of PD-RBD.</p>…”

Data_Sheet_1_Static and dynamic brain morphological changes in isolated REM sleep behavior disorder compared to normal aging.docx by Gilsoon Park (5737415)

“…</p>Patients/methods<p>In a longitudinal study of 18 patients with iRBD (age, 66.1 ± 5.7 years; 13 males; follow-up, 1.6 ± 0.6 years) and 24 age-matched healthy controls (age, 67.0 ± 4.9 years; 12 males; follow-up, 2.0 ± 0.9 years), all participants underwent multiple extensive clinical examinations, neuropsychological tests, and magnetic resonance imaging at baseline and follow-up. …”

Table_4_Long-term menopause exacerbates vaginal wall support injury in ovariectomized rats by regulating amino acid synthesis and glycerophospholipid metabolism.xlsx by Xia Yu (486142)

“…Purpose<p>Menopause is a risk factor for pelvic organ prolapse (POP) and is frequently associated with diminished vaginal wall support. …”

Table 1_Implementation of the International Code of Marketing of Breast-milk Substitutes and maternity protection: correlations with commercial milk formula consumption in East Asi... by Constance Ching (17267929)

“…</p>Findings<p>In 2019, EAP contributed to 63% of global CMF consumption, toddler formula was the highest category, a product that is unnecessary and unsuitable for consumption by young children. …”

Inhibitory Effects of <i>Trypanosoma cruzi</i> Sialoglycoproteins on CD4⁺ T Cells Are Associated with Increased Susceptibility to Infection by Marise Pinheiro Nunes (477302)

“…These molecules contain a unique type of glycosylation consisting of several sialylated <i>O</i>-glycans linked to the protein backbone via N-acetylglucosamine residues.…”

Image_3_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.PNG by Hongmei Li-Byarlay (5227208)

“…Israeli Acute Paralysis Virus (IAPV) is emerging as a model virus since its association with severe colony losses. …”

Hedgehog Promotes Neovascularization in Pancreatic Cancers by Regulating Ang-1 and IGF-1 Expression in Bone-Marrow Derived Pro-Angiogenic Cells by Kazumasa Nakamura (254851)

“…Since Hh signaling plays a crucial role during embryonic and postnatal vasculogenesis, we speculated that Hh ligand may act on tumor vasculature specifically focusing on bone marrow (BM)-derived cells.…”

The Effect of Propofol on Mitochondrial Fission during Oxygen-Glucose Deprivation and Reperfusion Injury in Rat Hippocampal Neurons - Fig 4 by Haibin Wang (219428)

“…<p><b>(A) mitochondrial fission proteins</b>, Drp1 and Fis1 expression was detected by Western blot analysis after I/R injury. …”

Image_2_Probiotic Lactobacillus rhamnosus GG Promotes Mouse Gut Microbiota Diversity and T Cell Differentiation.TIF by Chun-wei Shi (9856922)

“…Furthermore, LGG could effectively increase the expression of Th1-type cytokines (IFN-γ) and Th2 cytokines (IL-4) in CD4⁺ T cells, indicating that the proportion of Th1 and Th2 cells in mice with LGG treatment was in a high equilibrium state compared to the control group. …”

Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice by Reidun Aesoy (5562884)

DataSheet1_Prolonged administration of total glucosides of paeony improves intestinal immune imbalance and epithelial barrier damage in collagen-induced arthritis rats based on met... by Rui Xu (158313)

“…<p>Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and joint damage with complex pathological mechanisms. …”

Combined Oral Administration of Bovine Collagen Peptides with Calcium Citrate Inhibits Bone Loss in Ovariectomized Rats by JunLi Liu (3286419)

“…The present findings suggest that combined oral administration of bovine CPs with calcium citrate is a promising alternative for reducing bone loss in osteopenic postmenopausal women.…”

Expression of Suppressor of Cytokine Signaling 1 (SOCS1) Impairs Viral Clearance and Exacerbates Lung Injury during Influenza Infection by Keer Sun (673151)

“…Enhanced viral clearance in SOCS1^−/−IFN-γ^−/− mice coincided with a rapid onset of adaptive immune responses during acute infection, while their reduced lung injury was associated with decreased inflammatory cell infiltration at the resolution phase of infection. …”

Supplementary file 1_To assess the impact of individualized strategy and continuous glucose monitoring on glycemic control and mental health in pregnant women with diabetes.docx by Mengxue Liu (5953361)

“…</p>Results<p>FBG and 2hPBG significantly decreased post-intervention in both groups (P<0.001). …”

DataSheet_1_Babesia microti alleviates disease manifestations caused by Plasmodium berghei ANKA in murine co-infection model of complicated malaria.pdf by Iqra Zafar (10287965)

“…The key focus is to develop an efficient and long-term immunity to this disease via vaccination or therapeutic approach, and innovative strategies would enable us to achieve this target. Previously, using a mouse co-infection disease model, cross-protection was illustrated between Babesia microti and Plasmodium chabaudi. …”

DataSheet_1_Identification and validation of key molecules associated with humoral immune modulation in Parkinson’s disease based on bioinformatics.docx by Na Xing (823501)

“…</p>Methods<p>Firstly, we performed a series of bioinformatic analyses utilizing the expression profile of the peripheral blood mononuclear cell (PBMC) obtained from the GEO database (GSE100054, GSE49126, and GSE22491) to identify differentially expressed genes related to humoral immune regulatory mechanisms between PD and healthy controls. …”