Dendritic Cells from Crohn’s Disease Patients Show Aberrant STAT1 and STAT3 Signaling by Janne K. Nieminen (442997)

“…Studies on JAK/STAT signaling in DCs are, however, lacking in CD. We applied a flowcytometric single-cell-based phosphoepitope assay to evaluate STAT1 and STAT3 pathways in DC subsets from CD patients. …”

Data_Sheet_1_Liuwei Dihuang Decoction Alleviates Cognitive Dysfunction in Mice With D-Galactose-Induced Aging by Regulating Lipid Metabolism and Oxidative Stress via the Microbiota... by Baiyan Liu (12869393)

“…Liuwei Dihuang decoction (LW), a commonly applied Chinese medicine formula, is widely used for the treatment of aging-related diseases in China. …”

Data_Sheet_2_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.PDF by Jiarui Mi (11170284)

“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”

Video_3_Advanced Microscopy Reveals Complex Developmental and Subcellular Localization Patterns of ANNEXIN 1 in Arabidopsis.mp4 by Michaela Tichá (9207320)

“…Massive relocation and accumulation of ANN1-GFP at the PM and in Hechtian strands and reticulum in plasmolyzed cells suggest a possible osmoprotective role of ANN1-GFP during plasmolysis/deplasmolysis cycle. …”

DataSheet_1_microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition.csv by Bingfeng Luo (13718917)

“…Mimicry of miRNA-145-5p action raises the possibility of a novel target for treating Pca with bone metastases.…”

DataSheet_1_Additional prognostic value of polymorphisms within the 3′-untranslated region of programmed cell death pathway genes in early-stage breast cancer.pdf by Hanxi Chen (11578225)

“…</p>Methods<p>In this study, we genotyped 28 potentially functional single nucleotide polymorphisms (SNPs) in 23 PCD pathway genes in 1,177 patients with early-stage breast cancer (EBC) from a Han Chinese population. The median follow-up period was 174 months.…”

Image_1_Fengshi Gutong Capsule Attenuates Osteoarthritis by Inhibiting MAPK, NF-κB, AP-1, and Akt Pathways.tif by Yao-Xin Gao (5640092)

“…<p>Background and purpose: Fengshi Gutong capsule (FSGTC), a traditional herbal formula, has been used clinically in China for the treatment of arthritis. …”

Table1_Hydrogeochemistry of Hot Springs and the 2018 Mojiang M 5.9 Earthquake-Related Chemical Changes in the Simao Basin, China.docx by Qilin Li (535447)

“…Saline springs flowed through red beds and dissolved large amounts of halite, which is a rich source of Cl⁻and Na⁺ ions. …”

Transgelin-2 is upregulated on activated B-cells and expressed in hyperplastic follicles in lupus erythematosus patients by Kaori Kiso (4437109)

“…We also suggest that TAGLN2 could be used as a marker for activated B-cells.</p></div>…”

Table_2_High-Throughput Analysis of Water-Soluble Forms of Choline and Related Metabolites in Human Milk by UPLC-MS/MS and Its Application.XLSX by Daniela Hampel (683851)

“…In order to enable the rapid assessment of choline intake for exclusively breastfed infants and to further investigate the associations between milk choline and maternal and infant status and other outcomes, we have developed a simplified method for the simultaneous analysis of human milk choline, glycerophosphocholine, phosphocholine, and the less abundant related metabolites betaine, carnitine, creatinine, dimethylglycine (DMG), methionine, and trimethylamine N-oxide (TMAO) using ultraperformance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). …”

Image_3_Diabetic macrophage small extracellular vesicles-associated miR-503/IGF1R axis regulates endothelial cell function and affects wound healing.tif by Jianqiang Wang (573651)

“…<p>Diabetic foot ulcer (DFU) is a break in the skin of the foot caused by diabetes. …”

Image_6_Macrophages-Related Genes Biomarkers in the Deterioration of Atherosclerosis.TIFF by Yue Zheng (601811)

“…The hub DEMRGs and their interactions were analyzed using NetworkAnalyst 3.0 and for validation, the expressions of hub DEMRGs were analyzed using the GSE135055 and GSE116250 datasets as well as atherosclerosis and MI mice model.</p>Results<p>A total of 509 differentially expressed genes (DEGs) were correlated with the abundance of macrophages and were identified as DEMRGs (Pearson correlation coefficients (PCC) > 0.6), which were mainly enriched in extracellular structure organization, lysosomal membrane, MHC protein complex binding, and so on. …”

Table_2_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.XLSX by Hongmei Li-Byarlay (5227208)

“…Israeli Acute Paralysis Virus (IAPV) is emerging as a model virus since its association with severe colony losses. …”

Video_2_Advanced Microscopy Reveals Complex Developmental and Subcellular Localization Patterns of ANNEXIN 1 in Arabidopsis.mp4 by Michaela Tichá (9207320)

“…Massive relocation and accumulation of ANN1-GFP at the PM and in Hechtian strands and reticulum in plasmolyzed cells suggest a possible osmoprotective role of ANN1-GFP during plasmolysis/deplasmolysis cycle. …”

Estrogen and Progesterone Regulate p27kip1 Levels via the Ubiquitin-Proteasome System: Pathogenic and Therapeutic Implications for Endometrial Cancer by Kuang-Tzu Huang (132734)

“…The present studies demonstrate that E2 stimulates growth of ECA cell lines and normal primary endometrial epithelial cells (EECs) and induces MAPK-ERK1/2-dependent phosphorylation of p27 on Thr187, a prerequisite for p27 ubiquitylation by nuclear SCF-Skp2/Cks1 and subsequent degradation. …”

DataSheet1_Red Yeast Improves the Potential Safe Utilization of Solid Waste (Phosphogypsum and Titanogypsum) Through Bioleaching.docx by Haoming Chen (11880133)

“…<p>Phosphogypsum (PG) and titanium gypsum (TG), as a by-product (solid waste) in phosphate fertilizer and titanium dioxide industry, are causing serious environmental hazards. …”

DataSheet1_Dihydroartemisinin Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma Partially by Targeting AKT1 and p70S6K.pdf by Lili Zhu (219363)

“…<p>Dihydroartemisinin (DHA), a sesquiterpene lactone with endoperoxide bridge, is one of the derivatives of artemisinin. …”

Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX by Sara R. Oliveira (10972152)

Table_2_Diabetic macrophage small extracellular vesicles-associated miR-503/IGF1R axis regulates endothelial cell function and affects wound healing.csv by Jianqiang Wang (573651)

“…<p>Diabetic foot ulcer (DFU) is a break in the skin of the foot caused by diabetes. …”

Image_3_Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI.jpg by Neftali Ramirez (13251924)

“…In steady state, naïve B cells had increased cell death pathways and reduced cell metabolism pathways, while after stimulation, enhanced immune responses and decreased cell survival were detected. Using a multi-omics approach, our findings provide valuable insights into the impaired biology of naïve B cells from TACI mutation carriers.…”