Comparison of cilostazol- and resveratrol-stimulated P-LKB1 and P-AMPKα expressions in N2a cells that LKB1 is detectable, and in HeLa cells that lack LKB1. by So Youn Park (141327)

“…Proposed signal pathways for the neuroprotective effect of cilostazol against Aβ-induced neurotoxicity: Cilostazol upregulates autophagy through activating SIRT1/LKB1/AMPK1α signal pathways and depletes intracellular Aβ and APP-CTFβ accumulation, and thereby results in decreased neurotoxicity.…”

Summary maps of hedonic and aversive shifts produced by GABA-A agonism and AMPA antagonism. by Alexis Faure (247166)

“…Criteria for including a site as hedonic was an increase >10 in ‘liking’ reactions and a decrease or no change in ‘disliking’ reactions. …”

Myeloid lineage is affected by csrnp1a knockdown. by Jaime Espina (106906)

“…The <i>spi1</i> changes are accompanied by a significant decrease in proliferation (showed as the number of H3P within the <i>spi1</i> signal area) (E, F, and G). …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

Structural and Adhesive Properties of Cellulosic Mucilage: A Molecular-Level Investigation by Kamonthira Wichai (20386623)

“…The softer pectin polymers exhibit stronger adhesion than stiffer cellulose chains. Adhesion decreases with increasing polymer stiffness but plateaus beyond a threshold. …”

The inactivation of the acetyl-CoA acyltransferase 1 enzyme by the novel putative miRNA Oeu124369 leads to a decrease in Acetyl-CoA production and additionally, the deactivation of palmitoyl-protein thioesterase by the same miRNA results in a reduction in palmitic acid biosynthesis in the fatty acid elongation pathway. by Mohammad Hossein Pakdel (19837942)

“…<p>The inactivation of the acetyl-CoA acyltransferase 1 enzyme by the novel putative miRNA Oeu124369 leads to a decrease in Acetyl-CoA production and additionally, the deactivation of palmitoyl-protein thioesterase by the same miRNA results in a reduction in palmitic acid biosynthesis in the fatty acid elongation pathway.…”

Housing conditions specifically impaired long-term SRM (mean±SEM): A) Rats in group housing displayed a significant decrease in SIT during the second 5 min encounter (A2, empty bars) compared to the first (A1, gray bars), regardless of the time interval between the encounters. by Hadar Shahar-Gold (283031)

“…B) Socially isolated rats displayed a significant decrease in SIT measured during the second encounter only for intervals of 30 and 60 min but not for a 120 min interval. …”

A raincloud plot of the cuteness ratings. by Amanda C. Hahn (17241106)

Correlation of urinary CXCL1 level with proteinuria during follow-up period. by Yanfeng Zhao (308108)

“…<p>For patients with high baseline urinary CXCL1 levels (case 1 & case 2), the variation tendencies of urinary CXCL1 and proteinuria were almost the same (A & B). For patients with middle levels of baseline urinary CXCL1 (case 3 & case 4), although proteinuria relieved a lot, urinary CXCL1 levels just decreased a little (C & D). …”

The effect on plasma membrane expression of AMPA receptor subunits in hippocampal culture after presynaptic silencing with Bafilomycin (BAF). by Suleman Hussain (816864)

“…There is a slight, but significant decrease in labeling intensities after Bafilomycin treatment. …”

Metformin inhibits glutaminase activity in a dose dependent manner: from 17.5% at 10 mM up to 68% at 100 mM (A) (* p<0.05). by M. Mar Díaz-Herrero (646639)

“…<p>This effect, analyzed by Dixon plot, showed competitive inhibition kinetics, with a K_i of 14.28 mM (B). In Caco2 cells, metformin 20 mM showed 24% inhibition of glutaminase activity at 72 hours compared to control cultures (p<0.05) (glutamate production was decreased from 26.85±0.74 µM to 19.9±2.05 µM; p<0.05) (C).…”

Changes in the cell mortality and the percentages of clonal cells at different time points after PPP intervention. by Qi He (384033)

“…Cells at 0, 24, 48, 72, 96, and 168 h (7 d) after drug treatment were collected to calculate the mortality by Trypan Blue staining and smeared onto slides to detect the percentage of clonal cells using FISH. Over time, (A) the percentage of clonal cells progressively decreased. …”

Cumulative probabilities of achieving a CD4 count ≥650/μl (continuous lines) and a CD4/CD8 ratio ≥1 (dashed lines) after starting antiretroviral therapy as function of CD4 counts a... by Yusnelkis Milanés-Guisado (5774516)

Image4_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image1_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image3_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”

Image2_Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration.TIF by Manuel Soliño (5410001)

“…It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. …”