Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) by Saragusty, Joseph

“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em> by Bhavna Chawla (176976)

“…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em>^€-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”

Efmoroctocog Alfa: A Review in Haemophilia A by James E. Frampton (4995257)

“…</p> <p><b> </b></p> <p><b>Authorship and Conflict of interest</b> James E. Frampton is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. …”

Chemoresistance of Human Monocyte-Derived Dendritic Cells Is Regulated by IL-17A by Selma Olsson Åkefeldt (282869)

“…Immature dendritic cells were CD40^lowHLADR^low CD1a⁺ MCL1⁺, did not express CD14, CD68 or BCL2A1, and displayed a short 2-day lifespan. …”

Porcine Coro1A inhibit <i>H.parasuis</i> induced NF-κB activation. by Chong Liu (450204)

“…<p>(A) PK-15 cells were transfected with pNF-κB-luc (0.2 µg) and pRL-TK (0.05 µg), then cells were control-inoculated, live or heat-killed <i>H.parasuis</i> (10⁷ CFU) inoculated. …”

Reduction of NF-κB activation when porcine Coro1A was overexpressed. by Chong Liu (450204)

“…<p>(A) PK-15 cells were co-transfected with the pNF-κB-luc reporter plasmid (0.2 µg), pRL-TK plasmid (0.05 µg), along with 0.6 µg of the expression plasmid encoding porcine Coro1A protein. …”

Innovation, nightlights and a continuous measure of city size. by Saul Estrin (8629173)

HilD-activation results in a growth defect. by Doaa Osama Saleh (16353149)

“…Representative images are shown in the right panel. the same strains as in (A) were analysed. (C) Time-lapse microscopy analysis reveals a decreased cell elongation rate (left), a decrease in the maximal cell length (middle) as well as decreased length elongation during a division cycle (right) upon HilD induction. …”

Comparison of hatched blastocyst rates in Groups A and B. by Ayaka Fujishima (21221913)

Lack of i6A37 is not responsible for <i>maf1-</i>antisuppression phenotype. by Aneeshkumar G. Arimbasseri (840654)

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 4 by Nivedita Arora (3743413)

“…</b> Treatment with 100nM triptolide decreased the mRNA expression of Sp1, HSF1 and HSP70 in MKN28 and MKN45 gastric adenocarcinoma cells in a time (24–48 hours) dependent manner. …”

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 1 by Nivedita Arora (3743413)

“…</b> Treatment of moderately differentiated gastric adenocarcinoma cell line, MKN28 with triptolide decreases viability in a dose (25–100nM) as well as time (24–72 hours) dependent manner. …”

AoA results. by Eric Williams (101567)

“…Speech samples produced by 12 pwAD and 12 controls for the Carolinas Conversations Collection were analysed for noun, verb and pronoun counts and ratios, lexical diversity overall and among nouns and verbs, copula use, and frequencies and ages of acquisition (AoA) of nouns and verbs produced. pwAD used fewer nouns and a narrower range of words than controls, exhibiting signs of increased reliance on pronouns and decreased noun diversity. …”

Data_Sheet_1_A Tool for Computation of Changes in Na+, K+, Cl− Channels and Transporters Due to Apoptosis by Data on Cell Ion and Water Content Alteration.ZIP by Valentina E. Yurinskaya (2735836)

“…New experimental data for staurosporine-induced apoptosis of human lymphoma cells U937 have been obtained: the time course of changes in cellular K⁺, Na⁺, Cl⁻, and water content, as well as Rb⁺ fluxes as a marker of the Na/K pump activity. Using a newly developed computational tool, we found that alteration of ion and water balance was associated with a 55% decrease in the Na⁺/K⁺-ATPase rate coefficient over a 4-h period, with a time-dependent increase in potassium channel permeability, and a decrease in sodium channel permeability. …”

Statistics of three drug combination datasets were listed, including the number of drugs, principal drugs, adjuvant drugs, known synergistic combinations (A), and drug pairs withou... by Xing Chen (140292)

Protective effects of 0.2 μM cyclosporine A (CsA) on the sensitivity of mPTP opening under de-energized conditions. by Gonçalo C. Pereira (9022700)

Change of serum liver enzymes from BL to FU1 for HCV patients with steatosis (+S) and without steatosis (-S) and without fibrosis progression. by Monika Rau (826007)

Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer - Fig 2 by Nivedita Arora (3743413)

Changes in the replacement desorption amount caused by a single penetrant. by Dan Zhao (285025)