CPTA-glycine derivative, forming a hippurane-type spacer molecule, demonstrates a significantly decreased uptake in kidney at 1, 4 h p.i. and 4 h p.i. blocked with an excess of BN peptide. by Hanwen Zhang (307516)

“…<p>CPTA-glycine derivative, forming a hippurane-type spacer molecule, demonstrates a significantly decreased uptake in kidney at 1, 4 h p.i. and 4 h p.i. blocked with an excess of BN peptide.…”

Table_1_A T3SS Regulator Mutant HY9901 ΔaraC of Vibrio alginolyticus Decreased the Expression of HopPmaJ and Provided Protection to Danio rerio as a Live-Attenuated Vaccine.xls by Junlin Wang (4029803)

“…The swimming ability of ΔaraC decreased and exhibited a 2,600 times reduction in virulence to zebrafish. …”

The percentage of cells with protein aggregates cotransfected with αA- and αB-crystallin or R120G αB-crystallin (αBM) genes by Bing-Fen Liu (81305)

“…</p><p></p> The x-axis labels are either RED-αB- or the pairs of GFP-αA- and RED-αB-crystallin. A four-fold decrease of cells with protein aggregates was observed for cotransfection of αA- and αB-crystallin (the asterisk indicates a p=0.006), but only about a 1.5 fold decrease for cotransfection of αA- and αBM-crystallin (the double asterisk indicates a p=0.02). …”

Proposed Dyrk1A functions in regulating synaptic vesicle endocytosis. by Noriko Murakami (171144)

“…<p>Dyrk1A phosphorylated AP180 in cytosol. The phosphorylated AP180 may decrease its binding affinity to the AP2 complex; we hypothesize here that the decrease in such binding affinity would reduce recruitment of clathrin at the <i>nucleation</i> and <i>invagination</i> sites. …”

MiR-24 target Trib3 regulates hematopoietic gene expression networks. by Jeffrey L. Kurkewich (3044211)

“…EBF1 and Pax5 were significantly downregulated in ShTrb3 knockdown cells <b>F)</b> Trib3 knockdown in A20 cells resulted in decreased FoxO1 expression by immunoblot analysis. …”

Decrease in egg size and oviposition in <i>S</i>. <i>mansoni</i> females exposed to 20 μM GSK343 for 24 or 48 h. by Adriana S. A. Pereira (5900249)

Total viable immune cells and macrophages decrease acutely while neutrophils and macrophage increase at day 30 in parotid glands after 5Gy IR. by Jordan A. Gunning (18143970)

Cytosolic Ca²⁺ increase in endothelial cells and cytosolic Ca²⁺ decrease in smooth muscle cells induced by CNP. by Fernanda A. Andrade (558039)

Table_2_Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons.xlsx by Katalin A. Wilkinson (10193231)

“…Next, we evaluated 30 soluble analytes in QuantiFERON Gold in-tube (QFT) samples from the Ag stimulated and Nil tubes, during the first 6 months of ART in 30 patients. There was a significant decrease in IL-1alpha and IL-1beta (Ag-Nil) concentrations as well as MCP-1 (Nil), supporting decreased immune activation and inflammation. …”

Mean pace of decrease in mortality rates for White (front row) and Black (back row) women for the thirteen U.S. states from 1975 through 2010. by Mohammad A. Tabatabai (630217)

Glutamate exposure reduces MAP-2 immunostaining and induces changes in synaptic markers and cell adhesion molecule NCAM in the absence of neuronal death. by María Fernanda Podestá (639243)

“…<p>Hippocampal neurons in culture (DIV 12–13) were briefly exposed to 5 µM glutamate and evaluated 24 h later. (A) Microphotographs of hippocampal neurons in culture immunostained for MAP-2 or visualized by phase contrast microscopy. …”

BMP/SMAD and AKT/FoxO1 signaling is critical for mirn23a mediated immune cell regulation. by Jeffrey L. Kurkewich (3044211)

“…Overexpression of MyrAkt1 decreased B cell development and also abrogated the effect of mirn23a loss. …”

Mirn23a regulates critical hematopoietic gene expression networks to influence cell fate decisions. by Jeffrey L. Kurkewich (3044211)

“…Overexpression of miR-23acl or miR-23a alone results in significantly decreased expression of RLU when the Bach1 3’ UTR is present <b>D)</b> RNA was prepared from wildtype and <i>mirn23a</i>^<i>-/-</i> EML cells and analyzed by qRTPCR. …”

A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation by Chaitanya A. Kulkarni (9937661)

“…Delivery of diagnostic and therapeutic cargo directly into mitochondria is a powerful approach to study and treat these diseases. …”

Mirn23a regulates balance of MPP3/MPP4 progenitor populations. by Jeffrey L. Kurkewich (3044211)

“…<b>B)</b> The total MPP population was not significantly changed between wildtype and <i>mirn23a</i>^<i>-/-</i> mice. <b>C)</b> <i>Mirn23a</i>^<i>-/-</i> mice had significantly increased MPP1 and MPP3 populations and significantly decreased MPP2 and MPP4 populations. …”

DIAVIT protects against diabetes-induced glomerular ultra-structural changes. by Megan Stevens (3964886)

“…<p><b>A)</b> Representative glomerular electron micrographs from lean, db/db, and db/db + DIAVIT mice. …”

Mirn23a regulates essential B cell promoting genes to sustain commitment to the B cell lineage. by Jeffrey L. Kurkewich (3044211)

“…<b>B)</b> Ebf1, Pax5, Ikzf1, and Bach1 gene expression was significantly decreased in 70Z/3 cells overexpressing mirn23a cluster. …”

Bmi1 Loss in the Organ of Corti Results in p16^ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors <i>In Vitro</i> by Mohamed Bassiouni (3226770)

“…The cell cycle inhibitor p16^ink4a has been previously identified as a downstream target of Bmi1. …”

CsrA modulates the expression of a thiamine pyrophosphate (TPP) riboswitch element. by Tobias Sahr (3756775)

“…BlaM activity is significantly decreased in the mutant at the different conditions indicating a positive effect of CsrA on the <i>thi</i>-operon expression in <i>L</i>. …”

Lysosomal acidification and rate of proteolytic degradation in monocytes from CHM and control patients treated with Bafilomycin-A1 (BafA1). by Natalia V. Strunnikova (368335)

“…Intralysosomal acidification measurements were performed using <i>E. coli</i> BioParticles conjugated with a pH dependent dye (pHrodo). Treatment caused an increase in lysosomal pH as evident by a decrease in the fluorescence of BioParticles (confocal images, left panel vehicle no effect, right panel cells pre- treated with BafA1 for 30 min, decreased fluorescence). …”