Image_5_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…</p>Conclusions<p>In one of the largest, contemporary, real-world studies of patients with mPDAC, elevated CA 19-9 level at treatment initiation demonstrated a prognostic impact. …”

Image_3_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…</p>Conclusions<p>In one of the largest, contemporary, real-world studies of patients with mPDAC, elevated CA 19-9 level at treatment initiation demonstrated a prognostic impact. …”

Image_2_The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma.tif by Ben George (64738)

“…</p>Conclusions<p>In one of the largest, contemporary, real-world studies of patients with mPDAC, elevated CA 19-9 level at treatment initiation demonstrated a prognostic impact. …”

Association of methylenetetrahydrofolate reductase ( MTHFR ) gene polymorphisms (C677T and A1298C) with thyroid dysfunction: A meta-analysis and trial sequential analysis by Rui Yang (293531)

“…CC+CT/recessive model: OR = 2.07, 95% CI: 1.02-4.20, P = 0.04; TT vs. CC/homozygote model: OR = 2.35, 95% CI: 1.13-4.86, P = 0.02), while trial sequential analysis (TSA) revealed that it could be a false positive result. …”

Association of methylenetetrahydrofolate reductase ( MTHFR ) gene polymorphisms (C677T and A1298C) with thyroid dysfunction: A meta-analysis and trial sequential analysis by Rui Yang (293531)

“…CC+CT/recessive model: OR = 2.07, 95% CI: 1.02-4.20, P = 0.04; TT vs. CC/homozygote model: OR = 2.35, 95% CI: 1.13-4.86, P = 0.02), while trial sequential analysis (TSA) revealed that it could be a false positive result. …”

Table_3_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Image_4_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.TIF by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Table_5_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Table_6_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Image_3_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.TIFF by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Table_2_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Table_4_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Image_2_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.TIFF by Yishan Liu (10808097)

“…</p>Results<p>Of 6,872 critically ill patients, 3,886 (56.5%) had an elevated myoglobin level (≥150 ng/mL) at admission to ICU, and the in-hospital mortality significantly increased when myoglobin level exceeded 1,000 μg/mL. In LCTM, 2,448 patients were unsupervisedly divided into four groups, including the steady group (n = 1,606, 65.6%), the gradually decreasing group (n = 523, 21.4%), the slowly rising group (n = 272, 11.1%), and the rapidly rising group (n = 47, 1.9%). …”

Probing possible topologies of membrane tension-based inhibition of actin network assembly. by Alba Diz-Muñoz (236517)

“…<p><b>(A</b>) Schematic of the different network topologies investigated. Model I: WAVE2 complex dynamics in the absence of tension-mediated inhibition of actin polymerization (see also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002474#pbio.1002474.s006" target="_blank">S5B Fig</a> for early time points). …”

Image4_Achilles tendon compliance influences tendon loading more than Achilles tendon twist in Achilles tendinopathy: a musculoskeletal modeling approach.JPEG by Ine Mylle (13006902)

“…Results indicated that tendon compliance had a larger effect than tendon twist on triceps surae muscle forces. …”

Image3_Achilles tendon compliance influences tendon loading more than Achilles tendon twist in Achilles tendinopathy: a musculoskeletal modeling approach.JPEG by Ine Mylle (13006902)

“…Results indicated that tendon compliance had a larger effect than tendon twist on triceps surae muscle forces. …”

Gradients of cortical and laminar thickness against geodesic distance from primary areas. by Konrad Wagstyl (6714830)

“…By contrast, motor-frontal cortical thickness gradients exhibited decreases in thickness of the same layers. (B) The same trends were evident in the von Economo data set; however, because of the small number of recorded samples, the confidence intervals were larger and generally included zero. …”

Image2_Achilles tendon compliance influences tendon loading more than Achilles tendon twist in Achilles tendinopathy: a musculoskeletal modeling approach.JPEG by Ine Mylle (13006902)

“…Results indicated that tendon compliance had a larger effect than tendon twist on triceps surae muscle forces. …”

Image_5_Case report: B7-H3 CAR-T therapy partially controls tumor growth in a basal cell carcinoma patient.pdf by Gang Hu (132827)

“…The efficacy and safety of B7-H3 CAR-T therapy need to be further investigated with a larger cohort of patients. Although only one clinical case is reported here, the anti-B7-H3 CAR-T cell therapy should be considered as a treatment option for solid tumors in the future. …”

Direct and indirect climate controls predict heterogeneous early-mid 21^st century wildfire burned area across western and boreal North America by Thomas Kitzberger (2914124)

“…Changes in AAB range from strongly increasing (one order of magnitude increases in AAB) to moderately decreasing (more than halving of baseline AAB). …”