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481
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482
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
منشور في 2022"…Moreover, miRNA, piRNA, and snoRNAs expression profiles in iPSCs and original fibroblasts were assessed to identify the potential role of ncRNAs in enhancing iPSC generation, pluripotency, and differentiation. Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …"
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483
Mobility Competitiveness and Security: Expatriate Perspectives from Qatar
منشور في 2018"…Introduction: In order to create and sustain a competitive, knowledge-based economy, Qatar must be able to continually attract, retain and integrate expatriate workers. …"
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484
Tandem osmotic engine based on hydrogel particles with antipolyelectrolyte and polyelectrolyte effect fuelled by both salinity gradient modes
منشور في 2021"…In this study, we propose a new approach to attain energy by salinity gradient engines with pistons based on hydrogels possessing polyelectrolyte and antipolyelectrolyte effects in a tandem arrangement, providing energy in each salinity gradient mode in a repeatable manner. …"
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485
The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere
منشور في 2024"…However, a high concentration of biofertilizer combined with a low concentration of chemical fertilizers enhanced the eukaryotic diversity within the samples. …"
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486
Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.
منشور في 2023"…In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. …"
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487
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
منشور في 2023"…Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigated the anti-inflammatory effects of fluorinated benzofuran and dihydrobenzofuran derivatives in macrophages and in the air pouch model of inflammation, as well as their anticancer effects in the human colorectal adenocarcinoma cell line HCT116. …"
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488
Dynamic workload patterns prediction for proactive auto-scaling of web applications
منشور في 2018"…This may lead to inappropriate resource provisioning decisions. In this paper, we address these challenges by proposing a framework for prediction of dynamic workload patterns as follows. …"
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489
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
منشور في 2024"…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
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490
Profiling of the Differentially Expressed Genes of Inflammation and Angiogenesis of Human Brain Microvascular Endothelial Cells Evoked by Cell Injury In-Vitro to Mimic Acute Ischem...
منشور في 2020"…Acute IS (AIS) injury of PHBMEC is not well characterized in terms of its consequences on cell functions using genomic function profiling. In our study, we aimed to establish a new model of an acute in-vitro ischemic stroke, within a time limit of 2 hrs., with depriving whole nutrients and not just glucose, under hypoxic condition, in a model we created as oxygen nutrients deprivation (OND). …"
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491
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
منشور في 2024"…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …"
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492
Effect of biochars produced from solid organic municipal waste on soil quality parameters
منشور في 2017"…Select municipal organic wastes (newspaper, cardboard, woodchips and landscaping residues) individually or in a 25% blend of all four waste streams were used as feedstocks of biochars. …"
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493
DIFFERENTIAL EXPRESSION OF MICRORNAS BY ANTI-OBESITY TREATMENT SULFORAPHANE IN SKELETAL MUSCLE OF DIET-INDUCED OBESITY IN MICE
منشور في 2023"…Furthermore, we identified eight differentially expressed miRNAs in SFN-treated DIO mice, of which five were upregulated (mmu-miR-150-5p, mmu-miR-486a-3p, mmu-miR-126b-5p, mmu-miR-140-3p, mmu-miR-92a-3p) and three were downregulated (mmu-miR-101a-3p, mmu-miR-29c-3p, mmu-miR-3074-5p). …"
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494
Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media
منشور في 2021"…Herein, we have developed a biodegradable chitosan/lignosulfonate nanocomposite (CS@LS) as an efficient green biocide for the inhibition of SRBs biofilms. …"
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495
How to govern the non-cooperative amateur drones?
منشور في 2019"…However, non-cooperative UAVs may cause abuses of low-altitude airspace with potential security and safety problems, posing increasing challenges for low-altitude airspace management. In this article, we analyze the mechanisms to counter UAVs. Then GNSS spoofing on a UAV is described and our experimental results are reported. …"
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496
Scalable Containerized Pipeline for Real-time Big Data Analytics
منشور في 2022"…The traditional data-stream processing systems are inefficient in processing big data for detecting anomalies, classifications, clustering, and prediction in real-time using minimal resources. In this paper, we address this limitation by proposing a scalable pipeline for real-time processing of big data streams. …"
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497
Thermally assisted efficient electrochemical lithium extraction from simulated seawater
منشور في 2022"…Based on these understandings, we demonstrated that a thermally assisted electrochemical lithium extraction process could achieve rapid (36.8 mg g-1 day-1) and selective (51.79% purity) lithium extraction from simulated seawater with an ultrahigh Na+/Li+ molar ratio of 20,000. …"
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498
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
منشور في 2022"…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …"
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499
Burden and trend of diet-related non-communicable diseases in Australia and comparison with 34 OECD countries, 1990-2015: findings from the Global Burden of Disease Study 2015.
منشور في 2018"…Diet is a major determining factor for many non-communicable chronic diseases (NCDs). …"
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500
Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy
منشور في 2024"…Background & Objective: Chronic peripheral neuropathic pain (PNP) is a debilitating condition that is associated with many types of injury/diseases, including diabetes mellitus. …"
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