Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros by Mesmar, J.

“…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …”
Get full text
Get full text
Get full text

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank by Al-Hamdani, Mohammed

“…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R2 = 0.065, ΔF(7, 1724) = 3.34, p = 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …”
Get full text
Get full text
Get full text

The impacts of water level fluctuations from paddy fields and aquaculture ponds on wetland habitats for wintering waterbirds: Implications for wetland management by Cheng, Bo

“…Based on remote sensing image data and hydrological data, we selected Caizi Lake as a study site and comparatively analyzed the changes in wintering waterbird habitats in a water level sequence under the two scenarios. …”
Get full text
Get full text
Get full text

Dicarbonyl stress, protein glycation and the unfolded protein response by Rabbani, Naila

“…We propose that dicarbonyl stress, through increased formation of MG-glycated proteins, may be an important physiological stimulus of the UPR and Glo1 inducers may provide a route to effective suppression and therapy. …”
Get full text
Get full text
Get full text

The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. by Al-Asmakh, Maha

“…The main sources are the fetal membranes, including the amnion, chorion and decidua, and it is well established that stimuli [bacteria, bacterial endotoxins, interleukin (IL)-1beta, corticotrophin releasing hormone and platelet activating factor], as well as negative regulators (progesterone and IL-10), control the net output of PGs and cytokines in vitro. In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. …”
Get full text
Get full text

Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis by Elleuch, Jihen

“…However, the widespread use of B. thuringiensis δ-endotoxins has often been challenged by a lack of understanding of the target insect physiology as well as its midgut biochemistry.In the present investigation, we have evidenced and explained the toxicity improvement of Cry1Ac δ-endotoxins against Ephestia kuehniella larvae through in vivo combination with P20 helper protein. …”
Get full text
Get full text
Get full text

Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer by Ashour, Amal

“…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …”
Get full text
Get full text

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model by Abou-Saleh, Haissam

“…Although the observed toxic effect failed to affect embryo survival, whether a prolonged ChNP treatment may induce other potentially harmful effects remains to be elucidated. …”
Get full text
Get full text

Use and assessment of “e-plastics” as recycled aggregates in cement mortar by Makri, Chrysanthi

“…© 2019 Elsevier B.V. In this study we investigated the physical and mechanical properties of cement mortars, partially replaced with plastic (recycled plastic aggregate, RPA) recovered from WEEE (namely, “e-plastics”). …”
Get full text
Get full text

Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway by Sampath, Chethan

“…Phloretin and [6]-gingerol also decreased the levels of AGEs and CML levels, via Nrf2 pathway, enhancing GSH/GSSG ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue. …”
Get full text
Get full text

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall by Pintus, Gianfranco

“…Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arterial wall with aging. In this study, we hypothesized that a reduced expression of the protein vasorin plays a contributory role in magnifying Ang II-associated fibrogenic signaling in the VSMCs of the arterial wall with aging. …”
Get full text
Get full text

Climatic Aridity Gradient Modulates the Diversity of the Rhizosphere and Endosphere Bacterial Microbiomes of Opuntia ficus-indica by Karray, Fatma

Get full text
Get full text
Get full text

Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar by Bansal, Devendra

“…In contrast to Western countries, we report a varied genotypic profile of HPV with a high prevalence of low-risk HPV genotype 81 among the Arab women residing in Qatar.…”
Get full text
Get full text

Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose by Giordo, Roberta

“…Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic conditions. …”
Get full text
Get full text

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Ghantous, Crystal M.

“…Mechanically stretching the RPV significantly decreased APN protein expression after 24 hours and APN mRNA expression in a time-dependent manner in VSMCs. …”
Get full text
Get full text

Electrocatalytic cogeneration of reactive oxygen species for synergistic water treatment by Yang S.Y.

Get full text
Get full text

Independent and combined effects of antioxidant supplementation and circuit resistance training on selected adipokines in postmenopausal women by Saeidi, Ayoub

“…We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. …”
Get full text
Get full text
Get full text

The maxima in northerly wind speeds and wave heights over the Arabian Sea, the Arabian/Persian Gulf and the Red Sea derived from 40 years of ERA5 data by Aboobacker, V.M.

Get full text
Get full text
Get full text

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity by Gupta, Vijay

“…To overcome this issue, we engineered single-chain variable fragments (scFvs) against fibrillar α-syn, a putative disease-relevant form of α-syn. …”
Get full text
Get full text
Get full text

The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis by Kheraldine, Hadeel

“…Cationic G6 PAMAMs significantly decreased the viability of HER2-positive breast cancer cell lines down to 5.1% in SK-BR3 and to 5.7% in ZR-75 cells (p<0.001), in a dose and time-dependent fashion. …”
Get full text