Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice by Reidun Aesoy (5562884)

DataSheet1_Prolonged administration of total glucosides of paeony improves intestinal immune imbalance and epithelial barrier damage in collagen-induced arthritis rats based on met... by Rui Xu (158313)

“…<p>Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and joint damage with complex pathological mechanisms. …”

Combined Oral Administration of Bovine Collagen Peptides with Calcium Citrate Inhibits Bone Loss in Ovariectomized Rats by JunLi Liu (3286419)

“…The present findings suggest that combined oral administration of bovine CPs with calcium citrate is a promising alternative for reducing bone loss in osteopenic postmenopausal women.…”

Expression of Suppressor of Cytokine Signaling 1 (SOCS1) Impairs Viral Clearance and Exacerbates Lung Injury during Influenza Infection by Keer Sun (673151)

“…Enhanced viral clearance in SOCS1^−/−IFN-γ^−/− mice coincided with a rapid onset of adaptive immune responses during acute infection, while their reduced lung injury was associated with decreased inflammatory cell infiltration at the resolution phase of infection. …”

Supplementary file 1_To assess the impact of individualized strategy and continuous glucose monitoring on glycemic control and mental health in pregnant women with diabetes.docx by Mengxue Liu (5953361)

“…</p>Results<p>FBG and 2hPBG significantly decreased post-intervention in both groups (P<0.001). …”

DataSheet_1_Babesia microti alleviates disease manifestations caused by Plasmodium berghei ANKA in murine co-infection model of complicated malaria.pdf by Iqra Zafar (10287965)

“…The key focus is to develop an efficient and long-term immunity to this disease via vaccination or therapeutic approach, and innovative strategies would enable us to achieve this target. Previously, using a mouse co-infection disease model, cross-protection was illustrated between Babesia microti and Plasmodium chabaudi. …”

DataSheet_1_Identification and validation of key molecules associated with humoral immune modulation in Parkinson’s disease based on bioinformatics.docx by Na Xing (823501)

“…</p>Methods<p>Firstly, we performed a series of bioinformatic analyses utilizing the expression profile of the peripheral blood mononuclear cell (PBMC) obtained from the GEO database (GSE100054, GSE49126, and GSE22491) to identify differentially expressed genes related to humoral immune regulatory mechanisms between PD and healthy controls. …”

Comparative Plasma Lipidome between Human and Cynomolgus Monkey: Are Plasma Polar Lipids Good Biomarkers for Diabetic Monkeys? by Guanghou Shui (136742)

“…We established novel analytical approaches, which are based on a simple gradient elution, to quantify polar lipids in plasma including (i) glycerophospholipids (phosphatidylcholine, PC; phosphatidylethanolamine, PE; phosphatidylinositol, PI; phosphatidylglycerol, PG; phosphatidylserine, PS; phosphatidic acid, PA); (ii) sphingolipids (sphingomyelin, SM; ceramide, Cer; Glucocyl-ceramide, GluCer; ganglioside mannoside 3, GM3). …”

Table_1_Identification and validation of key molecules associated with humoral immune modulation in Parkinson’s disease based on bioinformatics.docx by Na Xing (823501)

“…</p>Methods<p>Firstly, we performed a series of bioinformatic analyses utilizing the expression profile of the peripheral blood mononuclear cell (PBMC) obtained from the GEO database (GSE100054, GSE49126, and GSE22491) to identify differentially expressed genes related to humoral immune regulatory mechanisms between PD and healthy controls. …”

Image_2_HLA-DR Expression Level in CD8+ T Cells Correlates With the Severity of Children With Acute Infectious Mononucleosis.tif by Yun Wang (32846)

“…The percentage of HLA-DR⁺ CD8⁺ T cells might be used as a prominent marker not only for the early diagnosis but also for indicating the severity of IM.…”

Image_3_Global, regional, and national years lived with disability due to blindness and vision loss from 1990 to 2019: Findings from the Global Burden of Disease Study 2019.TIF by Shasha Li (139491)

“…Purpose<p>This study aimed to provide a comprehensive assessment of burden estimates and the secular trend of blindness and vision loss, as measured by years lived with disability (YLDs), at the global, regional, and national levels.…”

DataSheet2_Guanxinkang Decoction Attenuates the Inflammation in Atherosclerosis by Regulating Efferocytosis and MAPKs Signaling Pathway in LDLR−/− Mice and RAW264.7 Cells.ZIP by Yifan Zhang (119570)

“…<p>Guanxinkang decoction (GXK), a traditional Chinese medicinal drug, is used to treat cardiovascular disease. …”

Table_1_HLA-DR Expression Level in CD8+ T Cells Correlates With the Severity of Children With Acute Infectious Mononucleosis.docx by Yun Wang (32846)

“…The percentage of HLA-DR⁺ CD8⁺ T cells might be used as a prominent marker not only for the early diagnosis but also for indicating the severity of IM.…”

DataSheet_1_Alteration of Intestinal Microbiota Composition in Oral Sensitized C3H/HeJ Mice Is Associated With Changes in Dendritic Cells and T Cells in Mesenteric Lymph Nodes.docx by Cui Zhou (1388874)

“…The intestinal bacterial community structure was analyzed, followed by Spearman correlation analysis between changed gut microbiota species and allergic parameters. Sensitization induced a noticeable allergic response to the gavage of OVA without adjuvant. …”

Average negative, positive, and net work data for all the walking conditions: Level (0°), downhill (−5°,−10°), and uphill (+5°,+10°) (n = 12). by Nikolaos Papachatzis (12959894)

“…<p>We compared level walking with downhill or uphill walking, and the horizontal straight lines indicated the pairwise significance between walking conditions. <b>(A)</b> The foot (i.e., distal-to-hindfoot) maintained its net negative work behavior across all walking conditions, with only downhill walking increasing the magnitude of the foot’s negative (p<0.001) and net negative (p = 0.013) work. …”

Data_Sheet_1_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.PDF by Jiarui Mi (11170284)

“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”

Tandem Mass Tag-Based Serum Proteome Profiling for Biomarker Discovery in Young Duchenne Muscular Dystrophy Boys by Tchilabalo D. Alayi (9465034)

“…In this study, we have standardized a highly specific and reproducible multiplexing mass spectrometry method using the tandem mass tag (TMT) strategy in combination with depletion of abundant proteins from serum and high-pH reversed-phase peptide fractionation. …”

Data_Sheet_1_The Relationship Between Lava Fountaining and Vent Morphology for the 2014–2015 Holuhraun Eruption, Iceland, Analyzed by Video Monitoring and Topographic Mapping.PDF by Tanja Witt (6092753)

“…Here we analyze records from lava fountain activity at distinguished vents, captured during the 2014–2015 Holuhraun eruption, and compare them with the morphology of spatter cones that developed. We conducted a fieldwork mapping project combining terrestrial laser scanning (TLS) and unmanned aerial vehicle (UAV) aerophoto techniques to characterize the cone morphologies. …”

Association of Nd:YAG laser and calcium-phosphate desensitizing pastes on dentin permeability and tubule occlusion by Vinícius MAXIMIANO (12833560)

“…Methodology Dentin specimens were exposed to 17% ethylene diamine tetra-acetic acid (EDTA) solution for 5 min and randomly allocated into five groups: G1, control (no treatment); G2, Nd:YAG laser (1 W, 10 Hz, 100 mJ, 85 J/cm2); G3, Laser + TeethmateTM Desensitizer; G4, Laser + Desensibilize Nano P; and G5, Laser+Nupro®. Specimens underwent a 5-day erosion-abrasion cycling. Hydraulic conductance was measured post-EDTA, post-treatment, and post-cycling. …”

Data_Sheet_3_Mendelian randomization in blood metabolites identifies triglycerides and fatty acids saturation level as associated traits linked to pancreatitis risk.PDF by Jiarui Mi (11170284)

“…</p>Results<p>In the primary analysis with 249 traits, we found that plasma triglycerides were positively associated with pancreatitis risk. Intriguingly, a large number of traits associated with saturation or unsaturation of fatty acids also demonstrated causal associations. …”