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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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48661
Oxygen consumption rate using EPR for a spheroid of ∼120<i>μ</i>m on day 7.
Published 2016“…<p>A decrease in oxygen concentration relative to time is explained by the formula -2.21T+623.77 (R<sup>2</sup> = 0.91), where <i>μ</i>mole of oxygen is represented by <i>μ</i>M and T is in minutes (160 min) and where the linear range occurs within the first 50 minutes. …”
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48662
Graph depicting estimates of the fraction of the remaining tumor that is sensitive to a therapy at various times during its treatment.
Published 2014“…The graph depicts curves drawn using the median g (0.00084) and d (0.0050) values of all patients enrolled in the sunitnib arm of the study and shows: (a) the actual tumor measurements as sum of the LDs (green line); (b) the gradual decrease in the fraction of tumor that is sensitive to therapy (black line); (c) the gradual increase in the fraction of tumor relatively resistant to therapy (red line); and (d) the fraction of the remaining tumor that is still sensitive to the therapy that is being administered (blue line). …”
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48663
Proportion of narrow-sense chip heritability, <i>A</i>(<i>N</i>) (Eq 37), captured by genome-wide significant SNPs as a function of sample size, <i>N</i>, for phenotypes shown in F...
Published 2020“…Left-to-right curve order is determined by decreasing . The prediction for education at sample size N = 1.1 million is <i>A</i>(<i>N</i>) = 0.27, so that the proportion of phenotypic variance explained is predicted to be 3.5%, in good agreement with 3.2% reported in [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008612#pgen.1008612.ref070" target="_blank">70</a>]. …”
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48664
Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake
Published 2013“…Taken together, these results show that Hsp60 may serve as a negative regulator in N-SMase2-induced dopamine re-uptake by decreasing the protein level of N-SMase2.…”
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48665
Evolutionary assembly drives community complexity.
Published 2025“…<p>With a mixture of ecological (i.e. via invasion) and evolutionary (i.e. via speciation) assembly events, we investigate the effect of the combination of invasion and evolution on the process of community assembly. …”
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48666
Supplementary Material for: Spinal Cord Stimulation for Parkinson’s Disease: A Systematic Review and Meta-Analysis of Pain and Motor Outcomes
Published 2023“…Nine studies involving 72 patients reported an estimated decrease of 4.43 points (95% confidence interval [CI]: 2.11; 6.75, <i>p</i> < 0.01) in UPDRS-III score, equivalent to a 14% reduction. …”
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48667
Objectively Measured Physical Activity and Sedentary Time during Childhood, Adolescence and Young Adulthood: A Cohort Study
Published 2013“…</p><p>Results</p><p>MVPA decreased from childhood to adolescence (−1 to −2.5 min/d per year of follow-up, P = 0.01 and <0.001, for girls and boys respectively) and also from adolescence to young adulthood (−0.8 to −2.2 min/d per year, P = 0.02 and <0.001 for girls and boys, respectively). …”
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48668
Data_Sheet_1_Altered functional connectivity and regional brain activity in a triple-network model in minimally conscious state and vegetative-state/unresponsive wakefulness syndro...
Published 2022“…These findings contribute to a better understanding of the underlying neural mechanism of functional connectivity and regional brain activity in DOC patients, and this triple-network model provides new connectivity pattern changes that may be integrated in future diagnostic tools based on the neural signatures of conscious states.…”
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48669
Table1_Stevens–Johnson syndrome induced by toripalimab in a previously EGFR-TKI-treated advanced lung adenocarcinoma patient harboring EGFR mutations 19 del/T790M/C797S in trans an...
Published 2023“…Stevens–Johnson syndrome (SJS) is a rare but potentially fatal complication of TKI and anti-PD-1 therapy. …”
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48670
DataSheet_1_CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma.docx
Published 2021“…</p>Results<p>We discovered that the levels of circFAM114A2 were decreased in urothelial carcinoma cell lines and tissues. …”
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48671
Fig 6 -
Published 2024“…<p>(a) Distribution (median and quartiles) of Sentinel-2 Maximum Surface Area Extent (MWAE) of the SR per Pléiades scene. …”
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48672
Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine i...
Published 2018“…VSV-Gag vaccine often caused systemic reactogenicity symptoms, including a viral syndrome (in 41%) of fever, chills, malaise/fatigue, myalgia, and headache; and decreased lymphocyte counts 1 day after vaccination.…”
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48673
Corrosion inhibition of Mild Steel at Elevated temperature in highly Acidic Brines using a green corrosion inhibitor
Published 2017“…Corrosion Inhibition of mild steel in 5 M Hydrochloric acid solution at different temperatures was investigated using a new green corrosion inhibitor (lauramidopropylamine oxide). …”
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48674
Dairy Wastage Footprint Analysis: A Farm-to-Fork Life Cycle Approach Across Dairy Supply Chain.
Published 2021“…Although the dairy sector is a primary source of milk, cheese, yogurt, and cream, livestock's supply chain, including their wastes, releases a considerable greenhouse gas such as methane, nitrous oxide, and carbon dioxide. …”
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48675
NaBu- resistant MDA-MB-231 cells displayed a high tumor initiation ability in vivo.
Published 2012“…Down regulation of <i>MET</i> with a treatment of NaBu leads to decrease the tumor incident rate effectively(18%), although con siRNA teated group resulted in a similar tumor incident rate with the intact cancer cell group(83%). …”
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48676
Table_2_High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation.DOCX
Published 2019“…Dysregulation of NET production and/or degradation can exert pathogenic effects, contributing to the pathogenesis of various diseases, including cystic fibrosis, autoimmune diseases and inflammatory conditions. By employing a phenotypic assay based on high-content imaging and analysis, we screened a library of biologically active compounds and identified vanilloids as a novel class of chemical compounds able to hinder NETosis induction and NET release. …”
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48677
Table_1_High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation.DOCX
Published 2019“…Dysregulation of NET production and/or degradation can exert pathogenic effects, contributing to the pathogenesis of various diseases, including cystic fibrosis, autoimmune diseases and inflammatory conditions. By employing a phenotypic assay based on high-content imaging and analysis, we screened a library of biologically active compounds and identified vanilloids as a novel class of chemical compounds able to hinder NETosis induction and NET release. …”
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48678
D−π–A Compounds with Tunable Intramolecular Charge Transfer Achieved by Incorporation of Butenolide Nitriles as Acceptor Moieties
Published 2015“…Chromophores where a polyenic spacer separates a 4<i>H</i>-pyranylidene or benzothiazolylidene donor and three different butenolide nitriles have been synthesized and characterized. …”
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48679
Isoalantolactone enhances radiation-induced G2/M cell cycle arrest in UMSCC-10A cells.
Published 2016“…Those led to an increase in the proportion of cells in G2/M phase; this also led to a slight increase in the number of cells in S phase and a decrease in the number of cells in G1 phase compared with the control. …”
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48680
Up/down regulation of reactions/paths of one compartment when a reaction from another compartment is deleted.
Published 2015“…Although deletion of the reactions shown here causes high up/down regulation in flux in the same compartment or in cytosol but here we focused to observe maximum flux FC in different compartment i.e., change in mitochondria when chloroplastic reaction is deleted and vice versa. Here, CoA, Pyr, IsoCit, <i>α</i>-KG, AcCoA, Cit, Cyt_red, Cyt_ox, Q, QH2, MalOxAc, _ext and _int indicate Coenzyme A, Pyruvate, isocitrate, alpha ketoglutarate, Acetyl-CoA, citrate, cytochrome c reductase, cytochrome c oxidase, ubiquinone, ubiquinol, malate oxaloacetate, external and internal, respectively.…”