IVIg does not decrease the antibody response against a thymus-independent antigen but recruits mature B cells to draining lymph nodes. by Laetitia Sordé (511583)

A targeted RNAi screen identifies 17 RNAi candidates that decrease the lifespan of the <i>isp-1;ctb-1</i> mutant. by Ludivine Walter (216669)

“…Only the RNAi clones that decrease the lifespan of the <i>isp-1;ctb-1</i> mutant by at least 10% are represented (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001084#pbio-1001084-t001" target="_blank">Table 1</a>). …”

NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission. by Jinwei Zhang (462455)

“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P <  0.001). …”

Image_9_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Fluorescent micrographs showing a decrease in EGFP emissions by RNAi-based gene silencing in <i>ex vivo</i> cultured cells. by Kazuyo Watanabe (11473473)

“…<p>Top panels (<b>A</b>-<b>C</b>) show the effects of the application of dsRNA using the transfection reagent (RNAi, procedure A), and bottom panels (<b>E</b>-<b>G</b>) show the effects of soaking with dsRNA without transfection reagent (RNAi, procedure B). …”

DNA damaged NEMO knockout MDFs show a decrease in IL-6 and IL-8 mRNA expression and protein secretion. by Patrick Meyer (3395285)

Image_14_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Supplementary Material for: Thiazolidinediones Decrease the Recurrence of Intracerebral Hemorrhage in Type 2 Diabetes Mellitus Patients: A Nested Case-Control Study by Chiu C.-D. (18492876)

Image_2_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIFF by Rohit Moudgil (540119)

<i>CPPED1</i> mRNA levels in preterm and term placentas. by Ravindra Daddali (8957867)

A General Method to Improve Fluorophores Using Deuterated Auxochromes by Jonathan B. Grimm (1297368)

“…Chemical strategies that suppress these undesirable pathwaysthereby increasing the brightness and photostability of fluorophoresare crucial for advancing the frontier of bioimaging. Here, we describe a general method to improve small-molecule fluorophores by incorporating deuterium into the alkylamino auxochromes of rhodamines and other dyes. …”

An example of a cell satisfying the checkpoint upon nocodazole washout. by Alma Beatrix Stier (20903134)

High glucose-containing media decreases mitochondrial membrane potential and ATP levels of in mixed glia cultures. by Yung-Cheng Huang (3443450)

Subjects:

DYRK1A affected NFATc2 protein phosphorylation. by Heng Liu (293917)

“…<p><b>A.</b> DYRK1A inhibitor harmine (2ug/ml) decreased NFATc1 expression (the image was flipped horizontally from the original picture). …”

Image_1_Cyclosporine A Regulates Influenza A Virus-induced Macrophages Polarization and Inflammatory Responses by Targeting Cyclophilin A.jpeg by Xiaoyuan Bai (12627670)

“…Mechanically, CsA decreases the polarization of macrophages into pro-inflammatory M1 phenotype and increases the polarization of macrophages into anti-inflammatory M2 phenotype. …”

WNT7A Regulation by miR-15b in Ovarian Cancer - Fig 5 by James A. MacLean II (2794756)

“…<p>(A) 5-aza-2’-dC treatment induces <i>miR-15b</i> expression (left) and decreases <i>WNT7A</i> expression (right) in OvCa cells. …”

Effects of Ionic Strength on the Functional Interactions between CYP2B4 and CYP1A2^† by Rusty W. Kelley (2514142)

“…With ionic interactions being sensitive to the surrounding ionic environment, monooxygenase activities were measured in both simple systems and mixed reconstituted systems as a function of ionic strength. PROD was found to be decreased at high ionic strength in both simple and mixed reconstituted systems, due to disruption of reductase−P450 complexes. …”

Effects of Ionic Strength on the Functional Interactions between CYP2B4 and CYP1A2^† by Rusty W. Kelley (2514142)

“…With ionic interactions being sensitive to the surrounding ionic environment, monooxygenase activities were measured in both simple systems and mixed reconstituted systems as a function of ionic strength. PROD was found to be decreased at high ionic strength in both simple and mixed reconstituted systems, due to disruption of reductase−P450 complexes. …”

The ATM/ATR-related Tra1 subunit shared by NuA4 and SAGA affects DSB repair but does not recapitulate combined Esa1/Gcn5 function. by Xue Cheng (6400607)

“…Depletion of the Tra1 subunit shared by NuA4 and SAGA leads to much decreased viability, while not as much as Esa1/Rpo21, but also clear sensitivity to DNA damage. …”